Patents by Inventor Yongzhong Li
Yongzhong Li has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20250092115Abstract: Provided are various embodiments relating to variant IgG Fc polypeptides of companion animals having increased Protein A binding for ease of purification, decreased C1q binding for reduced complement-mediated immune responses, decreased CD16 binding (e.g., for reduced antibody-dependent cellular cytotoxicity (ADCC) induction), increased stability, and/or the ability to form multimeric proteins. In addition, various embodiments relating to antibodies and fusion proteins comprising such variant IgG Fc polypeptides are provided. In various embodiments, such polypeptides may be used to treat companion animals, such as canines, felines, and equines.Type: ApplicationFiled: November 11, 2024Publication date: March 20, 2025Inventors: Hangjun ZHAN, Lam NGUYEN, Yongzhong LI, Fawn QIAN, Shyr Jiann LI, Richard CHIN
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Publication number: 20240418225Abstract: A transmission apparatus applied to an antenna, includes a first rotation member, a cross shaft, a second rotation member. The first end of the first rotation member is connected to a first linkage structure, and the second end of the first rotation member includes a pair of first pivot elements. The cross shaft includes a pair of first pivot mating elements and a pair of second pivot mating elements. Each first pivot mating element and a neighboring second pivot mating element are formed at an angle. The pair of first pivot mating elements rotatably cooperate with the pair of first pivot elements. The first end of the second rotation member is connected to the second linkage structure. The second end of the second rotation member includes a pair of second pivot elements. The pair of second pivot elements rotatably cooperate with the pair of second pivot mating elements.Type: ApplicationFiled: August 27, 2024Publication date: December 19, 2024Inventors: Youfang HUANGFU, Suyang BAO, Junyang HUANG, Yongzhong LI
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Publication number: 20240291146Abstract: A transmission apparatus includes a gear, a rack, and a fixture mechanism. The gear includes a first stopper and a pivot shaft. The first stopper is arranged at at least one end of a gear member extending along a longitudinal axis of the gear. The rack meshes with the gear in an assembly state and includes a second stopper corresponding to the first stopper. The fixture mechanism includes a gear fixing hole and a guidance groove. The gear rotates relative to the fixture mechanism via the pivot shaft. The pivot shaft passes through the gear fixing hole. The rack translates relative to the fixture mechanism through the guidance groove.Type: ApplicationFiled: May 9, 2024Publication date: August 29, 2024Inventors: Peng LIU, Yongzhong LI
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Publication number: 20240283147Abstract: A transmission mechanism includes: a drive shaft; and a stopper assembly, the stopper assembly including: a base, including a first thread; and a rotating component, positioned on the driving shaft, rotatable with the driving shaft, and including a second thread to engage the first thread, wherein at least one of the base and the rotating component is configured with a stopper; when the drive shaft rotates, the rotating component rotates with the drive shaft and slides relative to the base through an engagement of the first thread and the second thread; and when the stopper resists the base or the rotating component, a relative sliding between the base and the rotating component stops.Type: ApplicationFiled: April 25, 2024Publication date: August 22, 2024Inventors: Xu WANG, Yongzhong LI, Peng LIU, Junjie QIU, Qun CHEN
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Publication number: 20230416323Abstract: Provided are various embodiments relating to feline erythropoietin (EPO) polypeptide analogs with one or more additional glycosylation sites and methods of producing and using the same to treat anemia in companion animals. Also provided are various embodiments relating to EPO polypeptides having a mutation in the second binding site, polypeptides comprising an extracellular domain of EPO receptor, and methods of using the same for treating polycythemia in mammals.Type: ApplicationFiled: May 30, 2023Publication date: December 28, 2023Inventors: Hangjun Zhan, Lam Nguyen, Yongzhong Li, Qingyi Chu, Estela Garcia-Murillo, Victoria Leitman, Stephen Sundlof, Richard Chin, Shyr Jiann Li
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Patent number: 11742572Abstract: An antenna transmission device includes a shell, an output unit, and an input unit. The output unit is slidingly arranged at the shell and includes a rack. The input unit is at least partially arranged in the shell, meshes with the rack of the output unit, and is configured to drive the output unit to move linearly.Type: GrantFiled: March 7, 2022Date of Patent: August 29, 2023Assignees: PROSE TECHNOLOGIES (SUZHOU) CO., LTD., PROSE TECHNOLOGIES LLCInventors: Zhonghao Zou, Yongzhong Li
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Patent number: 11667686Abstract: Provided are various embodiments relating to feline erythropoietin (EPO) polypeptide analogs with one or more additional glycosylation sites and methods of producing and using the same to treat anemia in companion animals. Also provided are various embodiments relating to EPO polypeptides having a mutation in the second binding site, polypeptides comprising an extracellular domain of EPO receptor, and methods of using the same for treating polycythemia in mammals.Type: GrantFiled: June 5, 2018Date of Patent: June 6, 2023Assignee: Kindred Biosciences, Inc.Inventors: Hangjun Zhan, Lam Nguyen, Yongzhong Li, Qingyi Chu, Estela Garcia-Murillo, Victoria Leitman, Stephen Sundlof, Richard Chin, Shyr Jiann Li
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Patent number: 11417937Abstract: A phase shifter transmission device includes: a power mechanism, a driving rod, a plurality of transmission assemblies, and at least one row of phase shifters. The power mechanism is connected to the driving rod and configured to drive the driving rod to rotate. The plurality of transmission assemblies are connected to the driving rod, distributed along an axial direction of the driving rod, and driven by the driving rod to rotate synchronously. Each row of phase shifters includes a plurality of phase shifters distributed along the axial direction of the driving rod, and each phase shifter of each row of phase shifters is connected to the corresponding transmission assembly. The at least one row of phase shifters are configured, when being driven by the plurality of transmission assemblies, to synchronously adjust phases of radiated signals corresponding to the phase shifters.Type: GrantFiled: October 19, 2021Date of Patent: August 16, 2022Assignees: ROSENBERGER TECHNOLOGIES CO., LTD., ROSENBERGER TECHNOLOGIES LLCInventors: Yongzhong Li, Xu Wang, Ke Zhou, Zhonghao Zou, Jing Sun, Fan Li
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Publication number: 20220209404Abstract: An antenna transmission device includes a shell, an output unit, and an input unit. The output unit is slidingly arranged at the shell and includes a rack. The input unit is at least partially arranged in the shell, meshes with the rack of the output unit, and is configured to drive the output unit to move linearly.Type: ApplicationFiled: July 22, 2021Publication date: June 30, 2022Inventors: Zhonghao ZOU, Yongzhong LI
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Publication number: 20220209405Abstract: An antenna transmission device includes a shell, an output unit, and an input unit. The output unit is slidingly arranged at the shell and includes a rack. The input unit is at least partially arranged in the shell, meshes with the rack of the output unit, and is configured to drive the output unit to move linearly.Type: ApplicationFiled: March 7, 2022Publication date: June 30, 2022Inventors: Zhonghao ZOU, Yongzhong LI
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Patent number: 11355839Abstract: An antenna transmission device includes a shell, an output unit, and an input unit. The output unit is slidingly arranged at the shell and includes a rack. The input unit is at least partially arranged in the shell, meshes with the rack of the output unit, and is configured to drive the output unit to move linearly.Type: GrantFiled: July 22, 2021Date of Patent: June 7, 2022Assignees: ROSENBERGER TECHNOLOGIES CO., LTD., ROSENBERGER TECHNOLOGIES LLCInventors: Zhonghao Zou, Yongzhong Li
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Patent number: 11303019Abstract: Disclosed by the present invention is a transmission device for an antenna phase shifter, comprising a transmission input portion, a shift selection portion, and a transmission output portion; the transmission input portion is fully separated from the shift selection portion, by means of the shift selection portion, the transmission input portion establishes transmission connection with any output terminal of the transmission output portion, thereby performing phase adjustment on a phase shifter that is connected to the output terminal. In the present invention, two motors are responsible for power input and selection output respectively so as to select to drive any number of phase shifters; furthermore, the structure is compact, and output terminals of the transmission output portions may be spread out flat, being beneficial for antenna layout.Type: GrantFiled: March 10, 2020Date of Patent: April 12, 2022Assignee: ROSENBERGER TECHNOLOGIES CO., LTDInventors: Yongzhong Li, Zhonghao Zou
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Patent number: 11289803Abstract: An antenna element includes a base body. The base body includes a plate portion, a support column, and a metal layer. The plate portion is formed by non-metallic material. The at least one support column, each of the support column is connected to the plate portion. The metal layer covers the base body.Type: GrantFiled: July 12, 2021Date of Patent: March 29, 2022Assignees: ROSENBERGER TECHNOLOGIES CO., LTD., ROSENBERGER TECHNOLOGIES LLCInventors: Yongzhong Li, Xu Wang, Tao Jiang, Jing Sun
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Publication number: 20220064263Abstract: Provided are various embodiments relating to variant IgG Fc polypeptides of companion animals having increased Protein A binding for ease of purification, decreased C1q binding for reduced complement-mediated immune responses, decreased CD 16 binding (e.g., for reduced antibody-dependent cellular cytotoxicity (ADCC) induction), increased stability, and/or the ability to form multimeric proteins. In addition, various embodiments relating to antibodies and fusion proteins comprising such variant IgG Fc polypeptides are provided. In various embodiments, such polypeptides may be used to treat companion animals, such as canines, felines, and equines.Type: ApplicationFiled: December 26, 2019Publication date: March 3, 2022Applicant: Kindred Biosciences, Inc.Inventors: Hangjun Zhan, Lam Nguyen, Yongzhong Li, Fawn Qian, Shyr Jiann Li, Richard Chin
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Publication number: 20220037783Abstract: A phase shifter transmission device includes: a power mechanism, a driving rod, a plurality of transmission assemblies, and at least one row of phase shifters. The power mechanism is connected to the driving rod and configured to drive the driving rod to rotate. The plurality of transmission assemblies are connected to the driving rod, distributed along an axial direction of the driving rod, and driven by the driving rod to rotate synchronously. Each row of phase shifters includes a plurality of phase shifters distributed along the axial direction of the driving rod, and each phase shifter of each row of phase shifters is connected to the corresponding transmission assembly. The at least one row of phase shifters are configured, when being driven by the plurality of transmission assemblies, to synchronously adjust phases of radiated signals corresponding to the phase shifters.Type: ApplicationFiled: October 19, 2021Publication date: February 3, 2022Inventors: Yongzhong LI, Xu WANG, Ke ZHOU, Zhonghao ZOU, Jing SUN, Fan LI
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Patent number: 11201402Abstract: A phase shifter assembly includes: a first phase shifter including a first through-hole; a second phase shifter including a second through-hole and disposed at a side of the first phase shifter; a first gear including a third through-hole and disposed at a side of the second phase shifter facing away from the first phase shifter; a rack configured to drive, through driving the first gear, the second phase shifter to move relative to the first phase shifter, to adjust an electrical tilt angle of an antenna corresponding to the phase shifter assembly; and a first reversing mechanism disposed between the first gear and the rack and engaged with the first gear and the rack, respectively, making a direction of a component of a linear velocity at an electrical contact between the first phase shifter and the second phase shifter in a moving direction of the rack is opposite to the moving direction of the rack.Type: GrantFiled: July 9, 2021Date of Patent: December 14, 2021Assignees: ROSENBERGER TECHNOLOGIES CO., LTD., ROSENBERGER TECHNOLOGIES LLCInventors: Youfang Huangfu, Yongzhong Li, Suyang Bao, Min Shen, Dongfeng Ding, Yang Yang
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Publication number: 20210032305Abstract: Provided are various embodiments relating to feline erythropoietin (EPO) polypeptide analogs with one or more additional glycosylation sites and methods of producing and using the same to treat anemia in companion animals. Also provided are various embodiments relating to EPO polypeptides having a mutation in the second binding site, polypeptides comprising an extracellular domain of EPO receptor, and methods of using the same for treating polycythemia in mammals.Type: ApplicationFiled: June 5, 2018Publication date: February 4, 2021Applicant: Kindred Biosciences, Inc.Inventors: Hangjun Zhan, Lam Nguyen, Yongzhong Li, Qingyi Chu, Estela Garcia-Murillo, Victoria Leitman, Stephen Sundlof, Richard Chin, Shyr Jiann Li
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Publication number: 20200362034Abstract: Provided are various embodiments relating to variant IgG Fc polypeptides of companion animals having increased Protein A binding for ease of purification, decreased C1q binding for reduced complement-mediated immune responses, decreased CD16 binding (e.g., for reduced antibody-dependent cellular cytotoxicity (ADCC) induction, increased stability, and/or the ability to form heterodimeric proteins. In addition, various embodiments relating to antibodies and fusion proteins comprising such variant IgG Fc polypeptides are provided. Also provided are various embodiments relating to contiguous polypeptides comprising one or more variant GLP1 polypeptide(s) having improved serum half-life. Further provided are various embodiments relating to contiguous polypeptides or heterodimeric polypeptides comprising a GLP1 polypeptide and a glucagon polypeptide as a dual GLP1 receptor and glucagon receptor agonist.Type: ApplicationFiled: August 15, 2018Publication date: November 19, 2020Applicant: Kindred Biosciences, Inc.Inventors: Hangjun Zhan, Lam Nguyen, Yongzhong Li, Fawn Qian, Shyr Jiann Li
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Publication number: 20200212565Abstract: Disclosed by the present invention is a transmission device for an antenna phase shifter, comprising a transmission input portion, a shift selection portion, and a transmission output portion; the transmission input portion is fully separated from the shift selection portion, by means of the shift selection portion, the transmission input portion establishes transmission connection with any output terminal of the transmission output portion, thereby performing phase adjustment on a phase shifter that is connected to the output terminal. In the present invention, two motors are responsible for power input and selection output respectively so as to select to drive any number of phase shifters; furthermore, the structure is compact, and output terminals of the transmission output portions may be spread out flat, being beneficial for antenna layout.Type: ApplicationFiled: March 10, 2020Publication date: July 2, 2020Inventors: Yongzhong Li, Zhonghao Zou
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Publication number: 20180269563Abstract: A small base station antenna is disclosed, said small base station antenna having a length less than 0.4 m, and comprising a carriage, an antenna core assembly and an antenna shell, said small base station antenna capable of being mounted to a holding pole at one point through a mounting rack, characterized in that said small base station antenna further comprises a shock absorption part disposed between the carriage and the antenna shell so as to reduce the vibration frequency transmitted into the antenna core assembly. A method for reducing vibration frequency transmission in a small base station antenna is further disclosed. The present invention addresses the issue that a small base station antenna operates normally under high frequency vibration, such that the small base station antenna can pass the sinusoidal vibration test and random vibration test required by the industry, and can even pass the stricter impact test.Type: ApplicationFiled: August 5, 2015Publication date: September 20, 2018Inventors: Hongjun QIAN, Yongzhong LI, Junfeng YU