Patents by Inventor Yontao LU

Yontao LU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD OF IMPROVED SEQUENCING BY STRAND IDENTIFICATION
    Publication number: 20230167493
    Abstract: In some aspects, the present disclosure provides methods for identifying sequence variants, as well as methods of determining copy number of a genetic locus in a sample. Systems and kits for performing methods of the disclosure, as well as compositions produced by or useful in methods of the disclosure are also provided. In some embodiments, methods comprise extending 3? ends of polynucleotides by adding one or more pre-determined nucleotides. In some embodiments, methods comprise use of a strand-tagging sequence.
    Type: Application
    Filed: July 28, 2022
    Publication date: June 1, 2023
    Inventors: Malek FAHAM, Shengrong LIN, Ling Fung TANG, Yontao LU, Zhaohui SUN, Yingyu WANG, Li WENG
  • Method of improved sequencing by strand identification
    Patent number: 11427866
    Abstract: In some aspects, the present disclosure provides methods for identifying sequence variants, as well as methods of determining copy number of a genetic locus in a sample. Systems and kits for performing methods of the disclosure, as well as compositions produced by or useful in methods of the disclosure are also provided. In some embodiments, methods comprise extending 3? ends of polynucleotides by adding one or more pre-determined nucleotides. In some embodiments, methods comprise use of a strand-tagging sequence.
    Type: Grant
    Filed: May 16, 2017
    Date of Patent: August 30, 2022
    Assignee: ACCURAGEN HOLDINGS LIMITED
    Inventors: Malek Faham, Shengrong Lin, Ling Fung Tang, Yontao Lu, Zhaohui Sun, Yingyu Wang, Li Weng
  • METHODS AND COMPOSITIONS FOR EARLY CANCER DETECTION
    Publication number: 20220033916
    Abstract: Provided herein are methods and systems for detecting non-metastatic cancer in a subject, comprising measuring a total cfDNA fragment size distribution for the plurality of cfDNA nucleic acid molecules of the subject and comparing the total cfDNA fragment size distribution for the plurality of cfDNA nucleic acid molecules of the subject to the total cfDNA fragment size distribution for the plurality of cfDNA nucleic acid molecules from a healthy control.
    Type: Application
    Filed: August 18, 2021
    Publication date: February 3, 2022
    Inventors: Li WENG, Malek FAHAM, Tobias WITTKOP, Yontao LU, Ling Fung TANG
  • METHOD OF IMPROVED SEQUENCING BY STRAND IDENTIFICATION
    Publication number: 20200010884
    Abstract: In some aspects, the present disclosure provides methods for identifying sequence variants, as well as methods of determining copy number of a genetic locus in a sample. Systems and kits for performing methods of the disclosure, as well as compositions produced by or useful in methods of the disclosure are also provided. In some embodiments, methods comprise extending 3? ends of polynucleotides by adding one or more pre-determined nucleotides. In some embodiments, methods comprise use of a strand-tagging sequence.
    Type: Application
    Filed: May 16, 2017
    Publication date: January 9, 2020
    Inventors: Malek FAHAM, Shengrong LIN, Ling Fung TANG, Yontao LU, Zhaohui SUN, Yingyu WANG, Li WENG