Abstract: The present invention relates to a composition for detecting a marker for diagnosing an HER2 inhibitor-resistant cancer, a diagnostic kit including same, and a method for detecting the marker. More particularly, the present invention relates to a composition for detecting a maker for diagnosing an HER2 inhibitor-resistant cancer, a diagnostic kit including same, and a method for detecting the marker, wherein the present invention allows presence and absence of resistance to an HER2 inhibitor, which is typically prescribed to an HER2-positive cancer patient, in an HER2-positive cancer patient to be determined in an easier manner with remarkably high reliability.

Abstract: The present invention relates to a composition comprising an ischemic serum for promoting the activation of a stem cell, to a method for promoting the activation of a stem cell and to a stem cell, the activation of which is promoted by the composition or the method. The ischemic serum according to the present invention may stimulate the stem cell to facilitate the secretion of a growth factor, improve survival rate, improve mobility to an injured part, improve proliferation rate and maintain characteristics of the stem cell, thus promoting an activation of the stem cell such that the stem cell becomes suitable for transplantation of the stem cell to a patient having a brain injury.

Abstract: Provided is a hepatocyte nuclear factor 4 alpha (HNF4-?) antagonist and a use thereof. The HNF4-? antagonist selected in the present invention was confirmed to specifically bind to the ligand binding domain of HNF4-?, thereby inhibiting the activity of HNF4-?. The HNF4-? antagonist of the present invention can significantly reduce the expression of Wnt5a in a specific manner compared to that of the conventional known HNF4-? antagonists, and can also inhibit the growth of gastric cancer cells. Therefore, the HNF4-? antagonist of the present invention can not only be used as a pharmaceutical composition or a health functional food for preventing and treating cancer but can also be applied to a composition for treating or preventing diseases occurring due to the overexpression of HNF4-?.

Abstract: Provided is a hepatocyte nuclear factor 4 alpha (HNF4-?) antagonist and a use thereof. The HNF4-? antagonist selected in the present invention was confirmed to specifically bind to the ligand binding domain of HNF4-?, thereby inhibiting the activity of HNF4-?. The HNF4-? antagonist of the present invention can significantly reduce the expression of Wnt5a in a specific manner compared to that of the conventional known HNF4-? antagonists, and can also inhibit the growth of gastric cancer cells. Therefore, the HNF4-? antagonist of the present invention can not only be used as a pharmaceutical composition or a health functional food for preventing and treating cancer but can also be applied to a composition for treating or preventing diseases occurring due to the overexpression of HNF4-?.

Abstract: An apparatus for correcting a three dimensional space-angle of a drill for a dental hand piece, including: a housing provided on a fixing unit of the dental hand piece; a first sensing unit for measuring an angle of the housing in real-time; a second sensing unit for measuring an angle of a head portion or jaw of the patient in real-time; an operating unit for calculating the three-dimensional space angle of the drill; a setting unit for setting a reference three-dimensional space angle of the drill with respect to the tooth structure as a three-dimensional space angle that the operator is wanting among the three-dimensional space angles of the operating unit; and a display unit for displaying an alert message when the three-dimensional space angle of the operating unit deviates from a predetermined range of the reference three-dimensional space angle.

Abstract: Disclosed are an apparatus and method for detecting dementia and providing a dementia patient management service.

Abstract: Provided is a hepatocyte nuclear factor 4 alpha (HNF4-?) antagonist and a use thereof. The HNF4-? antagonist selected in the present invention was confirmed to specifically bind to the ligand binding domain of HNF4-?, thereby inhibiting the activity of HNF4-?. The HNF4-? antagonist of the present invention can significantly reduce the expression of Wnt5a in a specific manner compared to that of the conventional known HNF4-? antagonists, and can also inhibit the growth of gastric cancer cells. Therefore, the HNF4-? antagonist of the present invention can not only be used as a pharmaceutical composition or a health functional food for preventing and treating cancer but can also be applied to a composition for treating or preventing diseases occurring due to the overexpression of HNF4-?.

Abstract: A relay for automatically selecting a monitoring range for monitoring a parameter of an input source and a method for monitoring a parameter of an input source can be provided whereby the relay comprises one or more terminals for coupling to the input source; a plurality of switchable circuits coupled to the one or more terminals; a processing module coupled to the plurality of switchable circuits for automatically selecting a monitoring range from a plurality of monitoring ranges based on a value of the parameter of the input source, each monitoring range associated with one or more of said switchable circuits; and a relay switch being configured to provide or disrupt electrical communication to a circuit, based on a trigger signal provided by the processing module. A signal conditioning module may also be provided for e.g. conditioning signals prior to selection of the monitoring range.

Abstract: An apparatus for correcting a three dimensional space-angle of a drill for a dental hand piece, including: a housing provided on a fixing unit of the dental hand piece; a first sensing unit for measuring an angle of the housing in real-time; a second sensing unit for measuring an angle of a head portion or jaw of the patient in real-time; an operating unit for calculating the three-dimensional space angle of the drill; a setting unit for setting a reference three-dimensional space angle of the drill with respect to the tooth structure as a three-dimensional space angle that the operator is wanting among the three-dimensional space angles of the operating unit; and a display unit for displaying an alert message when the three-dimensional space angle of the operating unit deviates from a predetermined range of the reference three-dimensional space angle.

Abstract: The present invention relates to a composition for detecting a marker for diagnosing an HER2 inhibitor-resistant cancer, a diagnostic kit including same, and a method for detecting the marker. More particularly, the present invention relates to a composition for detecting a maker for diagnosing an HER2 inhibitor-resistant cancer, a diagnostic kit including same, and a method for detecting the marker, wherein the present invention allows presence and absence of resistance to an HER2 inhibitor, which is typically prescribed to an HER2-positive cancer patient, in an HER2-positive cancer patient to be determined in an easier manner with remarkably high reliability.

Abstract: The present invention relates to a composition comprising an ischemic serum for promoting the activation of a stem cell, to a method for promoting the activation of a stem cell and to a stem cell, the activation of which is promoted by the composition or the method. The ischemic serum according to the present invention may stimulate the stem cell to facilitate the secretion of a growth factor, improve survival rate, improve mobility to an injured part, improve proliferation rate and maintain characteristics of the stem cell, thus promoting an activation of the stem cell such that the stem cell becomes suitable for transplantation of the stem cell to a patient having a brain injury.

Abstract: A switching device and a method for switching states of a switching device are provided, the switching device comprising a housing; a switching module comprising a switching element, the switching module is configured to switch a state of the switching element upon generation of a switching signal; and an actuator for receiving a mechanical input and for facilitating generation of an electrical toggle signal, the toggle signal for causing the switching module to switch a state of the switching element.

Abstract: A relay for automatically selecting a monitoring range for monitoring a parameter of an input source and a method for monitoring a parameter of an input source can be provided whereby the relay comprises one or more terminals for coupling to the input source; a plurality of switchable circuits coupled to the one or more terminals; a processing module coupled to the plurality of switchable circuits for automatically selecting a monitoring range from a plurality of monitoring ranges based on a value of the parameter of the input source, each monitoring range associated with one or more of said switchable circuits; and a relay switch being configured to provide or disrupt electrical communication to a circuit, based on a trigger signal provided by the processing module. A signal conditioning module may also be provided for e.g. conditioning signals prior to selection of the monitoring range.

Abstract: A method and an apparatus for restoring defective memory cells are provided. The apparatus includes memory, a memory scan controller, which scans the memory to see if the memory is defective when a system starts operating and transmits resulting defect information to a memory controller, and the memory controller, which converts an external address applied from a system controller into an internal address for accessing the memory and replaces a defective cell in the memory with spare memory provided therein so that when a request for access to the defective cell is issued by the system controller, spare memory, rather than the defective cell, can be accessed by the system controller.

Abstract: An apparatus and method for automatically detecting a display mode to be used in a serial data interface (SDI) of a decoded video signal is provided. The apparatus for detecting a display mode includes a mode detector which detects a predetermined display mode by counting clock pulses generated between a present horizontal synchronous signal and a next horizontal synchronous signal from input decoded video signals, and a signal processing unit which converts formats of the decoded video signals so as to correspond to a display mode detected by the mode detector, serializes and outputs the decoded video signal. By deleting a control signal indicating a display mode, a control signal that does not coincide with processed data as a result of an incorrectly or incompatibly designed controller can be prevented.

Abstract: Conjugates of a biodegradable aliphatic polyester-based polymer with Tat49-57 peptide or a peptide chain containing the Tat49-57 peptide, and nanoparticles manufactured using the same. Intracellular permeability of the Tat49-57 peptide can be enhanced by exposing Tat peptide moieties to the surface of the nanoparticles.

Abstract: A method and an apparatus for restoring defective memory cells are provided. The apparatus includes memory, a memory scan controller, which scans the memory to see if the memory is defective when a system starts operating and transmits resulting defect information to a memory controller, and the memory controller, which converts an external address applied from a system controller into an internal address for accessing the memory and replaces a defective cell in the memory with spare memory provided therein so that when a request for access to the defective cell is issued by the system controller, spare memory, rather than the defective cell, can be accessed by the system controller.

Abstract: An apparatus and method for automatically detecting a display mode to be used in a serial data interface (SDI) of a decoded video signal is provided. The apparatus for detecting a display mode includes a mode detector which detects a predetermined display mode by counting clock pulses generated between a present horizontal synchronous signal and a next horizontal synchronous signal from input decoded video signals, and a signal processing unit which converts formats of the decoded video signals so as to correspond to a display mode detected by the mode detector, serializes and outputs the decoded video signal. By deleting a control signal indicating a display mode, a control signal that does not coincide with processed data as a result of an incorrectly or incompatibly designed controller can be prevented.

Abstract: The method involves forming a N well over a cell part and a P well over a periphery part of the semiconductor substrate, etching the N well and the P well to form trenches for a storage electrode and an element isolating film, forming an insulating film over the resulting structure, thereby filling the trench on the periphery part, sequentially forming a dielectric layer pattern and a storage electrode on the trench of the cell part, forming a storage electrode, forming an intermediate layer over the resulting structure, exposing the storage electrode, forming an undoped polysilicon layer over the resulting structure, thereby connecting the undoped polysilicon layer with the storage electrode, forming a polysilicon layer pattern and an intermediate insulating pattern, and forming a MOS transistor and a bit line over the polysilicon layer pattern of the cell part and the periphery part.