Patents by Inventor Yoshi Nara

Yoshi Nara has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted thiazole derivatives bearing 3-pyridyl groups, process for preparing the same and use thereof
    Patent number: 7067537
    Abstract: The present invention provides a pharmaceutical composition having a steroid C17,20-lyase inhibitory activity, which is useful as a prophylactic or therapeutic agent of prostatism, tumor such as breast cancer and the like, more particularly, a steroid C17,20-lyase inhibitor containing a compound represented by the formula: wherein A1 is an aromatic hydrocarbon group optionally having substituents or a heterocyclic group optionally having substituents, one of A2 and A3 is a hydrogen atom, a halogen atom, a C1-4 aliphatic hydrocarbon group optionally having substituents or an optionally esterified carboxyl group, the other of A2 and A3 is an aromatic hydrocarbon group optionally having substituents or a heterocyclic group optionally having substituents, and at least one of A1, A2 and A3 is a 3-pyridyl group optionally having substituents, or a salt thereof or a prodrug thereof.
    Type: Grant
    Filed: December 7, 2001
    Date of Patent: June 27, 2006
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Noritaka Kuroda, Yoshi Nara, Shohei Hashiguchi, Akihiro Tasaka, Masami Kusaka, Masuo Yamaoka, Tomohiro Kaku
  • Substituted thiazole derivatives bearing 3-pyridyl groups, process for preparing the same and use thereof
    Publication number: 20040072876
    Abstract: The present invention provides a pharmaceutical composition having a steroid C17,20-lyase inhibitory activity, which is useful as a prophylactic or therapeutic agent of prostatism, tumor such as breast cancer and the like, more particularly, a steroid C17,20-lyase inhibitor containing a compound represented by the formula: 1
    Type: Application
    Filed: June 4, 2003
    Publication date: April 15, 2004
    Inventors: Noritaka Kuroda, Yoshi Nara, Shohei Hashiguchi, Akihiro Tasaka, Masami Kusaka, Masuo Yamaoka, Tomohiro Kaku
  • Thienopyrimidine compounds, their production and use
    Patent number: 6340686
    Abstract: A compound of the formula: wherein R1 and R2 each is hydrogen, hydroxy, C1-4 alkoxy, C1-4 alkoxy-carbonyl or C1-4 alkyl which may be substituted; R3 is hydrogen, halogen, hydroxy or C1-4 alkoxy which may be substituted; or adjacent two R3 may form C1-4 alkylenedioxy; R4 is hydrogen or C1-4 alkyl; R6 is C1-4 alkyl which may be substituted or a group of the formula: wherein R5 is hydrogen or R4 and R5 may form heterocycle; and n is 0-5, or a salt thereof, has an excellent GnRH-antagonizing activity, and is useful for preventing or treating sex hormone-dependent diseases.
    Type: Grant
    Filed: May 16, 2000
    Date of Patent: January 22, 2002
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Shuichi Furuya, Nobuhiro Suzuki, Nobuo Choh, Yoshi Nara
  • Thienopyrimidine compounds, their production and use
    Patent number: 6297379
    Abstract: A compound of formula (I) wherein R1 and R2 each is hydrogen, hydroxy, C1-4 alkoxy, C1-4 alkoxy-carbonyl or C1-4 alkyl which may be substituted; R3 is hydrogen, halogen, hydroxy or C1-4 alkoxy which may be substituted; or adjacent two R3 may form C1-4 alkylenedioxy; R4 is hydrogen or C1-4 alkyl; R6 is C1-4 alkyl which may be substituted or a group of the formula (A) wherein R5 is hydrogen of R4 and R5 may form heterocycle; and n is 0-5, or a salt thereof, has an excellent GnRH-antagonizing activity, and is useful for preventing or treating sex hormone-dependent diseases.
    Type: Grant
    Filed: April 26, 2000
    Date of Patent: October 2, 2001
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Shuichi Furuya, Nobuhiro Suzuki, Nobuo Choh, Yoshi Nara