Abstract: RNA molecules for RNA interference to target a mutant allele with a point mutation, wherein the molecule has a nucleotide sequence complementary to a nucleotide sequence of a coding region of the mutant allele; and when counted from the base at the 5?-end in the nucleotide sequence complementary to the sequence of the mutant allele: a base at position 5 or 6 is mismatched with a base in the mutant allele; a base at position 10 or 11 is at the position of the point mutation and is identical to the base at the position of the point mutation in the mutant allele; the group at the 2?-position of the pentose in the ribonucleotide at position 8 is modified with OCH3, halogen, or LNA; and the group at the 2?-position of the pentose in the ribonucleotide at position 7 is not modified with any of OCH3, halogen, and LNA.

Abstract: A non-oriented electrical steel sheet of the present invention has a chemical composition capable of causing ?-? transformation, and contains 0.0005% to 0.0050% of Ti, in which, in a case where an area ratio of grains having a crystal orientation of an {hkl}<uvw> orientation (within a tolerance of 10°) when measured by EBSD is denoted as Ahkl-uvw, A411-011 is 15.0% or more, and the non-oriented electrical steel sheet has an average grain size of 10.0 ?m to 40.0 ?m.

Abstract: There is provided a non-oriented electrical steel sheet having a predetermined chemical composition, in which an area fraction of a crystal structure A composed of crystal grains having a grain size of 100 ?m or more is 1% to 30% in a cross section parallel to a rolled plane of the non-oriented electrical steel sheet, an average grain size of a crystal structure B which is a crystal structure other than the crystal structure A is 40 ?m or less, and a Vickers hardness HvA of the crystal structure A and a Vickers hardness HvB of the crystal structure B satisfy Equation 1 ((HvA2+HvB2)/2?(HvA+HvB)2/4?7.0).

Abstract: This non-oriented electrical steel sheet includes a base material having a chemical composition including Si: 3.7 to 4.8%, wherein a recrystallization rate is less than 100% in terms of an area fraction, the following Formula (i) and Formula (ii) are satisfied, and the tensile strength is more than 700 MPa. 4.3?Si+sol. Al+0.5×Mn?4.9??(i) (B50(0°)+2×B50(45°)+B50(90°))/4?1.

Abstract: A non-oriented electrical steel sheet of the present invention has a chemical composition capable of causing ?-? transformation, in which, in a case where an area ratio of grains having a crystal orientation of an {hkl}<uvw>orientation (within a tolerance of 10°) when measured by EBSD is denoted as Ahkl-uvw, A411?011 is 15.0% or more, and the non-oriented electrical steel sheet has an average grain size of 10.0 ?m to 40.0 ?m.

Abstract: A non-oriented electrical steel sheet of the present invention has a chemical composition capable of causing ?-? transformation, and contains 0.0005% to 0.0050% of Ti, in which, in a case where an area ratio of grains having a crystal orientation of an {hkl}<uvw> orientation (within a tolerance of 10°) when measured by EBSD is denoted as Ahkl-uvw, A411-011 is 15.0% or more, and the non-oriented electrical steel sheet has an average grain size of 10.0 ?m to 40.0 ?m.

Abstract: This non-oriented electrical steel sheet includes a base steel sheet (10); and an insulation coating (20) formed on a surface of the base steel sheet (10), in which the insulation coating (20) contains a metal phosphate and an organic resin, an arithmetic mean of a center line average roughness Ra75 of the insulation coating (20) in a rolling direction of the base steel sheet (10) and a center line average roughness Ra75 of the insulation coating (20) in a direction perpendicular to the rolling direction is 0.20 to 0.50 ?m, and the amount of nitrogen in the insulation coating (20) is 0.05 to 5.00 mass %.

Abstract: This non-oriented electrical steel sheet contains a base material having a chemical composition including, in mass %, Si: 3.2 to 4.5%, wherein the tensile strength is 550 MPa or more, and a ratio (P120B/Fe700B)B between a peak-to-peak height Fe700B of Fe at 700 eV and a peak-to-peak height P120B of P at 120 eV when crystal grain boundaries are measured through Auger electron spectroscopy is not more than twice a ratio (P120i/Fe700i)i between a peak-to-peak height Fe700i of Fe at 700 eV and a peak-to-peak height P120i of P at 120 eV when the inside of crystals is measured through Auger electron spectroscopy.

Abstract: This non-oriented electrical steel sheet has a predetermined chemical composition, and in which the tensile strength is 580 MPa or more, the average grain size of a recrystallization part of base iron is 50 ?m or less, and in inclusions having an equivalent circle diameter of 1 ?m or more and an S content of 5 mass % or more contained in base iron, the number of inclusions having a Mg content of more than 5 mass % and a Mn content of 5 mass % or more is 5 times or more the number of inclusions having a Mg content of 5 mass % or less and a Mn content of 5 mass % or more.

Abstract: A non-oriented electrical steel sheet according to the present invention has a chemical composition in which ?-? transformation can occur and which contains at least, in terms of mass %, at most 0.010% of C, 1.50% to 4.00% of Si, 0.0001% to 1.0% of sol. Al, at most 0.010% of S, at most 0.010% of N, and a total of 2.50% to 5.00% of at least one selected from the group consisting of Mn, Ni, and Cu, with the balance including Fe and impurities, wherein when an average grain size of {411} crystal grains is defined as d411 and an average grain size of {111} crystal grains is defined as d111, d411/d111?1.10.

Abstract: This non-oriented electrical steel sheet includes a base metal having a predetermined chemical composition satisfying the expression [Si+0.5×Mn?4.3], and an average grain size of the base metal is more than 40 ?m and 120 ?m or less.

Abstract: A rotating electrical machine includes a stator, a rotor, and a casing that accommodates the stator and the rotor, in which a {111}<211> orientation intensity (A) of a core material of the stator is in a range of 2 to 30, a {111}<211> orientation intensity (B) of a core material of the rotor is in a range of 1 to 15, and both the orientation intensities satisfy a relationship of an expression (1) A>B.

Abstract: A non-oriented electrical steel sheet including a base metal that has a chemical composition including, in mass%, C: 0.0010 to 0.0040%, Si: 4.0 to 5.0%, Mn: 0.20% or less Al: 0.010% or more and less than 0.050%, P: 0.030% or less, S: 0.0030% or less, N: 0.0005 to 0.0030%, O: 0.0100 to 0.0400%, Ca: less than 0.0010%, Ti: less than 0.0050%, Nb: less than 0.0050%, Zr: less than 0.0050%, V: less than 0.0050%, Cu: less than 0.20%, Ni: less than 0.50%, Sn: 0 to 0.05%, Sb: 0 to 0.05%, and a balance: Fe and impurities, in which the base metal has an O content of less than 0.0050% in a region excluding a portion from a surface of the base metal to a position of 10 µm in a depth direction of the base metal.

Abstract: A non-oriented electrical steel sheet including a base metal that has a chemical composition including, in mass %, C: 0.0010 to 0.0040%, Si: 3.5 to 4.9%, Mn: 0.05 to 0.20%, Al: 0.05 to 0.45%, P: 0.030% or less, S: 0.0030% or less, N: 0.0030% or less, O: 0.0100 to 0.0400%, Ca: less than 0.0010%, Ti: less than 0.0050%, Nb: less than 0.0050%, Zr: less than 0.0050%, V: less than 0.0050%, Cu: less than 0.20%, Ni: less than 0.50%, Sn: 0 to 0.05%, Sb: 0 to 0.05%, and a balance: Fe and impurities, and satisfying [4.0?Si+Al?5.0], in which the base metal has an O content of less than 0.0050% in a region excluding a portion from a surface of the base metal to a position of 10 ?m in a depth direction of the base metal.

Abstract: A chemical composition of a base metal of a non-oriented electrical steel sheet contains, by mass %, C: 0.0050% or less, Si: 3.8% to 5.0%, Mn: exceeding 0.2% and less than 2.0%, P: 0.030% or less, S: 0.0030% or less, Al: 0.005% or more and less than 0.050%, N: 0.0005% to 0.0030%, Ti: less than 0.0050%, Nb: less than 0.0050%, Zr: less than 0.0050%, V: less than 0.0050%, Cu: less than 0.20%, Ni: less than 0.50%, Sn: 0% to 0.10%, Sb: 0% to 0.10%, a remainder: Fe and impurities. [Si+0.5×Mn?4.3] is satisfied and the average grain size of the base metal is in a range of 10 to 80 ?m.

Abstract: An electrical steel sheet is described, which has an insulating coating on its surface. The insulating coating is free of chromium and comprises plate-like particles of inorganic compound and a metal phosphate. The plate-like particles of inorganic compound are in the form of secondary particles, which are formed by aggregating primary particles, and present in an amount of not less than 0.1 parts by mass and not greater than 20 parts by mass, with respect to 100 parts by mass of the metal phosphate. The secondary particles have an average particle diameter of no less than 0.05 ?m and no greater than 5 ?m, and have a specific surface area of 1 to 80 m2/g. The primary particles have an aspect ratio of 50 to 1000. The electrical steel sheet has excellent heat resistance, corrosion resistance, appearance, and insulating properties.

Abstract: A grain-oriented electrical steel sheet includes a steel layer and an insulation coating arranged in directly contact with the steel layer thereon. The steel layer includes, as a chemical composition, by mass %, 2.9 to 4.0% of Si, 2.0 to 4.0% of Mn, 0 to 0.20% of Sn, and 0 to 0.20% of Sb. In the steel layer, a silicon content and a manganese content expressed in mass % satisfy 1.2%?Si?0.5×Mn?2.0%, and a tin content and an antimony content expressed in mass % satisfy 0.005%?Sn+Sb?0.20%.

Abstract: This electrical steel sheet contains, as a chemical composition, by mass %, C: 0.0035% or less, Si: 2.00% to 3.50%, Mn: 2.00% to 5.00%, P: 0.050% or less, S: 0.0070% or less, Al: 0.15% or less, N: 0.0030% or less, Ni: 0% to 1.00%, Cu: 0% to 0.10%, and a remainder: Fe and impurities, in which an X-ray random intensity ratio in a {100} <011> crystal orientation on a sheet surface is 15.0 to 50.0, and magnetic flux densities in 0°, 22.5°, and 45° directions from a rolling direction each satisfy [1.005×(B50 (0°)+B50 (45°))/2?B50 (22.5°)].

Abstract: A non-oriented electrical steel sheet has a predetermined chemical composition, and when an average value of Mn concentrations in a range from a surface of a base iron to a position where a depth from the surface of the base iron is 2 ?m is set to [Mn2], and an Mn concentration at a position where a depth from the surface of the base iron is 10 ?m is set to [Mn10], the base iron satisfies the following expression 1. 0.1?[Mn2]/[Mn10]?0.

Abstract: A non-oriented electrical steel sheet includes, as a chemical composition, by mass %: C: 0.0015% to 0.0040%; Si: 3.5% to 4.5%; Al: 0.65% or less; Mn: 0.2% to 2.0%; Sn: 0% to 0.20%; Sb: 0% to 0.20%; P: 0.005% to 0.150%; S: 0.0001% to 0.0030%; Ti: 0.0030% or less; Nb: 0.0050% or less; Zr: 0.0030% or less; Mo: 0.030% or less; V: 0.0030% or less; N: 0.0010% to 0.0030%; O: 0.0010% to 0.0500%; Cu: less than 0.10%; Ni: less than 0.50%; and a remainder including Fe and impurities, in which a product sheet thickness is 0.10 mm to 0.30 mm, an average grain size is 10 ?m to 40 ?m, an iron loss W10/800 is 50 W/Kg or less, a tensile strength is 580 MPa to 700 MPa, and a yield ratio is 0.82 or more.