Patents by Inventor Yoshiaki Tsuda

Yoshiaki Tsuda has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Phenol derivatives, their preparation and the use thereof
    Patent number: 4906662
    Abstract: Disclosed are phenol derivatives of the formula ##STR1## wherein R.sup.1 is a substituted phenyl group, R.sup.2 and R.sup.3 are C.sub.1 -C.sub.6 alkyl group and of the formula ##STR2## wherein R.sup.8, R.sup.9 and R.sup.10 are C.sub.1 -C.sub.6 alkyl and the like and A is H, C.sub.1 -C.sub.6 alkylsulfonyl and the like substituents. These compounds and some related compounds have anti-inflammatory activity and lipoxygenase inhibitory activity.
    Type: Grant
    Filed: January 27, 1987
    Date of Patent: March 6, 1990
    Assignee: Otsuka Pharmaceutical Factory, Inc.
    Inventors: Kinji Hashimoto, Kiyoto Goto, Ken-ichi Kanai, Yoshiaki Tsuda
  • Proline derivatives
    Patent number: 4886813
    Abstract: Disclosed is a proline derivative of the formula ##STR1## or a pharmaceutically acceptable salt thereof. These derivatives have useful utilities such as activity of inhibiting angiotensin converting enzyme.
    Type: Grant
    Filed: April 28, 1986
    Date of Patent: December 12, 1989
    Assignee: Otsuka Pharmaceutical Factory, Inc.
    Inventors: Shizuo Nakamura, Makoto Inoue, Masatoshi Inai, Yoshiaki Tsuda
  • Carboxamide compounds
    Patent number: 4822780
    Abstract: A carboxamide compound of the formula: ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4 and X are as defined and pharmaceutically acceptable salts thereof, and composition containing the compound are disclosed.The compound is useful as a calcium antagonistic agent and an antiinflammatory agent.
    Type: Grant
    Filed: July 8, 1987
    Date of Patent: April 18, 1989
    Assignee: Otsuka Pharmaceutical Factory, Inc.
    Inventors: Yoshihiko Tsuda, Yoshiaki Tsuda
  • Proline derivatives
    Patent number: 4642355
    Abstract: This invention provides a proline derivative represented by the formula ##STR1## wherein: R.sub.1 is C.sub.5 -C.sub.14 alkyl, C.sub.2 -C.sub.6 alkenyl, C.sub.3 -C.sub.8 cycloalkyl-C.sub.1 -C.sub.6 alkyl or a group ##STR2## (wherein R.sub.5 is hydrogen, C.sub.1 -C.sub.14 alkyl or phenyl and R.sub.6 is hydrogen or C.sub.1 -C.sub.6 alkyl);R.sub.2 is hydrogen or C.sub.1 -C.sub.6 alkyl;R.sub.3 is C.sub.1 -C.sub.6 alkyl;R.sub.4 is hydrogen, C.sub.1 -C.sub.6 alkyl or phenyl-C.sub.1 -C.sub.6 alkyl; andn is 0, 1 or 2,and a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: February 20, 1985
    Date of Patent: February 10, 1987
    Assignee: Otsuka Pharmaceutical Factory, Inc.
    Inventors: Shizuo Nakamura, Makoto Inoue, Yoshiaki Tsuda