Patents by Inventor Yoshie Takaki

Yoshie Takaki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD OF MEASURING NEPRILYSIN ACTIVITY
    Publication number: 20090298775
    Abstract: The present invention provides a method of measuring the activity of neprilysin, etc. More specifically, the present invention provides a method of measuring the activity of neprilysin in nerve cells; a method of screening a protein, a peptide or a compound enhancing the activity or expression of neprilysin in nerve cells by measuring the activity of neprilysin; a method of enhancing the activity or expression of neprilysin; and so on. Thus, the compound enhancing the activity and/or expression of neprilysin, which is obtained by the screening method characterized by using the method of measuring the activity of neprilysin in accordance with the present invention, is useful as a preventive and/or therapeutic agent for Alzheimer's disease. The method of measuring the activity of the present invention can be used for presymptomatic diagnosis of Alzheimer's disease.
    Type: Application
    Filed: June 24, 2009
    Publication date: December 3, 2009
    Applicants: Riken, Takeda Pharmaceutical Company, Ltd.
    Inventors: Takaomi Saido, Nobuhisa Iwata, Satoshi Tsubuki, Yoshie Takaki, Takashi Saito, Tadashi Nakaya
  • Method of measuring neprilysin activity
    Patent number: 7572574
    Abstract: The present invention provides a method of measuring the activity of neprilysin, etc. More specifically, the present invention provides a method of measuring the activity of neprilysin in nerve cells; a method of screening a protein, a peptide or a compound enhancing the activity or expression of neprilysin nerve cells by measuring the activity of neprilysin; a method of enhancing the activity or expression of neprilysin; and so on. Thus, the compound enhancing the activity and/or expression of neprilysin, which is obtained by the screening method characterized by using the method of measuring the activity of neprilysin in accordance with the present invention, is useful as a preventive and/or therapeutic agent for Alzheimer's disease. The method of measuring the activity of the present invention can be used for presymptoms diagnosis of Alzheimer's disease.
    Type: Grant
    Filed: April 24, 2003
    Date of Patent: August 11, 2009
    Assignees: Riken, Takeda Pharmaceutical Company, Ltd
    Inventors: Takaomi Saido, Nobuhisa Iwata, Satoshi Tsubuki, Yoshie Takaki, Takashi Saito, Tadashi Nakaya
  • Method of measuring neprilysin activity
    Publication number: 20060008842
    Abstract: The present invention provides a method of measuring the activity of neprilysin, etc. More specifically, the present invention provides a method of measuring the activity of neprilysin in nerve cells; a method of screening a protein, a peptide or a compound enhancing the activity or expression of neprilysin nerve cells by measuring the activity of neprilysin; a method of enhancing the activity or expression of neprilysin; and so on. Thus, the compound enhancing the activity and/or expression of neprilysin, which is obtained by the screening method characterized by using the method of measuring the activity of neprilysin in accordance with the present invention, is useful as a preventive and/or therapeutic agent for Alzheimer's disease. The method of measuring the activity of the present invention can be used for presymptoms diagnosis of Alzheimer's disease.
    Type: Application
    Filed: April 24, 2003
    Publication date: January 12, 2006
    Applicant: Takeda Pharmaceutical Company Limited
    Inventors: Takaomi Saido, Nobuhisa Iwata, Satoshi Tsubuki, Yoshie Takaki, Takashi Saito