Patents by Inventor Yoshifumi Maya

Yoshifumi Maya has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230112418
    Abstract: In a compound of the present invention, in a macroscopic view of a chemical structure thereof, a chelating moiety is located at the center of the structure, an atomic group containing an albumin binding moiety binds to one side of the chelating moiety, and an atomic group containing a target molecule binding moiety binds to the other side of the chelating moiety. The chelating moiety is also preferably DOTA or a derivative thereof. The target molecule binding moiety preferably has a structure to bind to a target molecule expressed in a cancer tissue. The present invention also provides a radioactive labeled compound in which the compound is coordinated to a radioactive metal ion.
    Type: Application
    Filed: March 4, 2021
    Publication date: April 13, 2023
    Applicants: NIHON MEDI-PHYSICS CO., LTD., KYOTO UNIVERSITY
    Inventors: Yoshifumi MAYA, Masahiro ONO, Shimpei IIKUNI
  • Patent number: 11266753
    Abstract: Provided are a compound represented by the following formula (1): wherein X1 represents a hydrogen atom or a halogen atom, X2 represents a fluorine atom or a nitrile group, and X3 represents a radioactive halogen atom, or a salt thereof, and a medicament including the same.
    Type: Grant
    Filed: December 20, 2018
    Date of Patent: March 8, 2022
    Assignees: NIHON MEDI-PHYSICS CO., LTD., NATIONAL HOSPITAL ORGANIZATION
    Inventors: Akihiro Izawa, Yuki Okumura, Yurie Fukui, Hiroaki Ichikawa, Yoshifumi Maya, Miho Ikenaga, Hiroyuki Okudaira, Yoshihiro Doi, Mitsuhide Naruse
  • Publication number: 20210060186
    Abstract: Provided are a compound represented by the following formula (1): wherein X1 represents a hydrogen atom or a halogen atom, X2 represents a fluorine atom or a nitrile group, and X3 represents a radioactive halogen atom, or a salt thereof, and a medicament including the same.
    Type: Application
    Filed: December 20, 2018
    Publication date: March 4, 2021
    Applicants: Nihon Medi-Physics Co., Ltd., National Hospital Organization
    Inventors: Akihiro IZAWA, Yuki OKUMURA, Yurie FUKUI, Hiroaki ICHIKAWA, Yoshifumi MAYA, Miho IKENAGA, Hiroyuki OKUDAIRA, Yoshihiro DOI, Mitsuhide NARUSE
  • Publication number: 20190255199
    Abstract: The present invention addresses the problem of providing a technique for detecting a lesion of a heart disease in a non-invasive manner. The present invention provides a non-invasive diagnostic imaging agent for a heart disease, which contains a radioactively labeled compound capable of binding to an aldosterone synthase or a salt thereof as an active ingredient.
    Type: Application
    Filed: June 9, 2017
    Publication date: August 22, 2019
    Applicant: Nihon Medi-Physics Co., Ltd.
    Inventor: Yoshifumi MAYA
  • Patent number: 9211350
    Abstract: A compound represented by the following formula (1), or a salt thereof: wherein R1 is a radioactive halogen substituent, 0 to 2 of A1, A2, A3 and A4 represent N, and the rest represent —(CH)— is effective as a diagnostic imaging probe targeting amyloid. A diagnostic agent for Alzheimer's disease contains a compound represented by the above formula (1) or a salt thereof. After administration to a patient, the compound and the diagnostic agent for Alzheimer's disease transfer into the patient's brain, and indicate good accumulation on amyloid deposited in the brain.
    Type: Grant
    Filed: May 29, 2012
    Date of Patent: December 15, 2015
    Assignee: NIHON MEDI-PHYSICS CO., LTD.
    Inventors: Yuki Okumura, Yoshifumi Maya, Yoshinari Shoyama, Takako Onishi
  • Patent number: 9149546
    Abstract: A compound that is effective as a diagnostic imaging probe that targets amyloid including is represented by the following formula (1), or salt thereof: wherein R1 is a radioactive halogen substituent, A1 and A2 independently represent CH or N. A diagnostic agent for Alzheimer's disease includes the compound represented by the above formula or a salt thereof. The above compound and the above diagnostic agent for Alzheimer's disease transfer into brain after administration, and indicate good accumulation on amyloid deposited in the brain.
    Type: Grant
    Filed: May 18, 2012
    Date of Patent: October 6, 2015
    Assignee: NIHON MEDI-PHYSICS CO., LTD.
    Inventors: Yuki Okumura, Yoshifumi Maya, Yoshinari Shoyama, Takako Onishi
  • Publication number: 20140228569
    Abstract: A compound that is effective as a diagnostic imaging probe that targets amyloid including is represented by the following formula (1), or salt thereof: wherein R1 is a radioactive halogen substituent, A1 and A2 independently represent CH or N. A diagnostic agent for Alzheimer's disease includes the compound represented by the above formula or a salt thereof. The above compound and the above diagnostic agent for Alzheimer's disease transfer into brain after administration, and indicate good accumulation on amyloid deposited in the brain.
    Type: Application
    Filed: May 18, 2012
    Publication date: August 14, 2014
    Inventors: Yuki Okumura, Yoshifumi Maya, Yoshinari Shoyama, Takako Onishi
  • Publication number: 20140121377
    Abstract: A compound represented by the following formula (1), or a salt thereof: wherein R1 is a radioactive halogen substituent, 0 to 2 of A1, A2, A3 and A4 represent N, and the rest represent —(CH)— is effective as a diagnostic imaging probe targeting amyloid. A diagnostic agent for Alzheimer's disease contains a compound represented by the above formula (1) or a salt thereof. After administration to a patient, the compound and the diagnostic agent for Alzheimer's disease transfer into the patient's brain, and indicate good accumulation on amyloid deposited in the brain.
    Type: Application
    Filed: May 29, 2012
    Publication date: May 1, 2014
    Inventors: Yuki Okumura, Yoshifumi Maya, Yoshinari Shoyama, Takako Onishi