Patents by Inventor Yoshifumi Takahara
Yoshifumi Takahara has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11959872Abstract: The present invention provides a method for accurately measuring a blood component despite uneven distribution of blood introduced into a capillary. The measurement method according to the present invention is characterized in that a plurality of electrode systems for measuring the hematocrit are provided in a capillary of a biosensor to measure the hematocrit at different positions in the capillary. By measuring the hematocrit at the plurality of positions in the capillary as described above, the hematocrit can be measured mom accurately despite uneven distribution of blood introduced into the capillary.Type: GrantFiled: March 1, 2019Date of Patent: April 16, 2024Assignee: PHC Holdings CorporationInventors: Masaki Fujiwara, Yoshifumi Takahara, Takaaki Fujii, Setsuko Yano, Fuminori Kutsuna
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Patent number: 11639912Abstract: A reagent layer of a sensor contains as a mediator a quinone compound having a hydrophilic functional group, phenanthrenequinone, and/or a phenanthrenequinone derivative. The quinone compound has a lower redox potential than a conventional mediator, so interfering substances have less effect on detection results with this sensor.Type: GrantFiled: July 23, 2020Date of Patent: May 2, 2023Assignee: PHC HOLDINGS CORPORATIONInventors: Yoshifumi Takahara, Takahiro Nakaminami, Shin Ikeda
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Patent number: 11467118Abstract: The present invention provides a method for accurately measuring a blood component despite uneven distribution of blood introduced into a capillary. The measurement method according to the present invention is characterized in that a plurality of electrode systems for measuring the hematocrit are provided in a capillary of a biosensor to measure the hematocrit at different positions in the capillary. By measuring the hematocrit at the plurality of positions in the capillary as described above, the hematocrit can be measured more accurately despite uneven distribution of blood introduced into the capillary.Type: GrantFiled: August 3, 2018Date of Patent: October 11, 2022Assignee: PHC Holdings CorporationInventors: Masaki Fujiwara, Yoshifumi Takahara, Takaaki Fujii, Junko Nakayama, Setsuko Yano, Fuminori Kutsuna
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Publication number: 20210010969Abstract: The present invention provides a method for accurately measuring a blood component despite uneven distribution of blood introduced into a capillary. The measurement method according to the present invention is characterized in that a plurality of electrode systems for measuring the hematocrit are provided in a capillary of a biosensor to measure the hematocrit at different positions in the capillary. By measuring the hematocrit at the plurality of positions in the capillary as described above, the hematocrit can be measured mom accurately despite uneven distribution of blood introduced into the capillary.Type: ApplicationFiled: March 1, 2019Publication date: January 14, 2021Inventors: Masaki FUJIWARA, Yoshifumi TAKAHARA, Takaaki FUJII, Setsuko YANO, Fuminori KUTSUNA
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Publication number: 20200371060Abstract: The present invention provides a method for accurately measuring a blood component despite uneven distribution of blood introduced into a capillary. The measurement method according to the present invention is characterized in that a plurality of electrode systems for measuring the hematocrit are provided in a capillary of a biosensor to measure the hematocrit at different positions in the capillary. By measuring the hematocrit at the plurality of positions in the capillary as described above, the hematocrit can be measured more accurately despite uneven distribution of blood introduced into the capillary.Type: ApplicationFiled: August 3, 2018Publication date: November 26, 2020Inventors: Masaki FUJIWARA, Yoshifumi TAKAHARA, Takaaki FUJII, Junko NAKAYAMA, Setsuko YANO, Fuminori KUTSUNA
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Publication number: 20200348255Abstract: A reagent layer of a sensor contains as a mediator a quinone compound having a hydrophilic functional group, phenanthrenequinone, and/or a phenanthrenequinone derivative. The quinone compound has a lower redox potential than a conventional mediator, so interfering substances have less effect on detection results with this sensor.Type: ApplicationFiled: July 23, 2020Publication date: November 5, 2020Inventors: Yoshifumi TAKAHARA, Takahiro NAKAMINAMI, Shin IKEDA
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Patent number: 10761044Abstract: A reagent layer of a sensor contains as a mediator a quinone compound having a hydrophilic functional group, phenanthrenequinone, and/or a phenanthrenequinone derivative. The quinone compound has a lower redox potential than a conventional mediator, so interfering substances have less effect on detection results with this sensor.Type: GrantFiled: November 10, 2015Date of Patent: September 1, 2020Assignee: PHC HOLDINGS CORPORATIONInventors: Yoshifumi Takahara, Takahiro Nakaminami, Shin Ikeda
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Publication number: 20160061764Abstract: A reagent layer of a sensor contains as a mediator a quinone compound having a hydrophilic functional group, phenanthrenequinone, and/or a phenanthrenequinone derivative. The quinone compound has a lower redox potential than a conventional mediator, so interfering substances have less effect on detection results with this sensor.Type: ApplicationFiled: November 10, 2015Publication date: March 3, 2016Inventors: Yoshifumi TAKAHARA, Takahiro NAKAMINAMI, Shin IKEDA
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Patent number: 9212380Abstract: A reagent layer of a sensor contains as a mediator a quinone compound having a hydrophilic functional group, phenanthrenequinone, and/or a phenanthrenequinone derivative. The quinone compound has a lower redox potential than a conventional mediator, so interfering substances have less effect on detection results with this sensor.Type: GrantFiled: August 30, 2010Date of Patent: December 15, 2015Assignee: PANASONIC HEALTHCARE HOLDINGS CO., LTD.Inventors: Yoshifumi Takahara, Takahiro Nakaminami, Shin Ikeda
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Patent number: 9046479Abstract: A biosensor detects a target substance contained in a liquid sample and includes an insulating base plate having a recess formed in a portion that is thinner than the surrounding part, a working electrode and a counter electrode, at least one of which is disposed in the recess. A reaction reagent is disposed in the recess and reacts with a specific substance in the liquid sample.Type: GrantFiled: June 24, 2009Date of Patent: June 2, 2015Assignee: PANASONIC HEALTHCARE HOLDINGS CO., LTD.Inventors: Yoshifumi Takahara, Noriyoshi Terashima, Takaaki Fujii
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Patent number: 8845966Abstract: The measurement device comprises a sensor holder to which is removable to a biosensor. The sensor holder has measurement-use connection terminals that are in contact with the electrode system in the biosensor and are used to take off signals required for measuring the specific component, and thermocouple-use connection terminals that are in contact with the thermocouple in the biosensor and are used to take off the thermoelectromotive force signals.Type: GrantFiled: December 7, 2012Date of Patent: September 30, 2014Assignee: Panasonic CorporationInventors: Takaaki Fujii, Yoshifumi Takahara, Noriyoshi Terashima
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Patent number: 8349259Abstract: A biosensor includes a cavity for holding a sample, an electrode system for measuring the sample concentration in the cavity, and a thermocouple for obtaining temperature information during measurement. A measurement device includes a reference temperature junction sensor or an environmental temperature sensor for measuring the temperature of reference temperature junctions of the thermocouple. A temperature compensation measures the temperature difference between a measuring junction and a reference temperature junctions of the thermocouple, and specifies the temperature of a reference temperature junction, thereby using the temperature information as the temperature of a measurement component and performing accurate temperature compensation from the measuring junction temperature information and the environmental temperature information with respect to the measured values.Type: GrantFiled: June 16, 2009Date of Patent: January 8, 2013Assignee: Panasonic CorporationInventors: Takaaki Fujii, Yoshifumi Takahara, Noriyoshi Terashima
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Patent number: 8287704Abstract: A liquid sample measurement apparatus of the present invention is provided with a timer for measuring the time from when a biosensor is attached to a liquid sample measurement device which measures the concentration of a specific component in a liquid sample that is applied to the biosensor to when the liquid sample is applied to the biosensor, and correction based on the time measured by the timer is performed to the measurement result of the concentration of the specific component in the liquid sample that is applied to the biosensor. Thereby, the measurement precision can be enhanced with utilizing the correction algorithm in which the ambient temperature and the temperature of the biosensor itself are considered.Type: GrantFiled: January 13, 2012Date of Patent: October 16, 2012Assignee: Panasonic CorporationInventors: Teppei Shinno, Yoshifumi Takahara
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Patent number: 8287718Abstract: A liquid sample measurement apparatus of the present invention is provided with a timer for measuring the time from when a biosensor is attached to a liquid sample measurement device which measures the concentration of a specific component in a liquid sample that is applied to the biosensor to when the liquid sample is applied to the biosensor, and correction based on the time measured by the timer is performed to the measurement result of the concentration of the specific component in the liquid sample that is applied to the biosensor. Thereby, the measurement precision can be enhanced with utilizing the correction algorithm in which the ambient temperature and the temperature of the biosensor itself are considered.Type: GrantFiled: July 4, 2007Date of Patent: October 16, 2012Assignee: Panasonic CorporationInventors: Teppei Shinno, Yoshifumi Takahara
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Publication number: 20120152763Abstract: A reagent layer (4) of a sensor (1) contains as a mediator a quinone compound having a hydrophilic functional group, phenanthrenequinone, and/or a phenanthrenequinone derivative. The quinone compound has a lower redox potential than a conventional mediator, so interfering substances have less effect on detection results with this sensor 1.Type: ApplicationFiled: August 30, 2010Publication date: June 21, 2012Inventors: Yoshifumi Takahara, Takahiro Nakaminami, Shin Ikeda
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Publication number: 20120103806Abstract: A liquid sample measurement apparatus of the present invention is provided with a timer (122) for measuring the time from when a biosensor (30) is attached to a liquid sample measurement device (110a) which measures the concentration of a specific component in a liquid sample that is applied to the biosensor (30) to when the liquid sample is applied to the biosensor (30), and correction based on the time measured by the timer (122) is performed to the measurement result of the concentration of the specific component in the liquid sample that is applied to the biosensor (30). Thereby, the measurement precision can be enhanced with utilizing the correction algorithm in which the ambient temperature and the temperature of the biosensor itself are considered.Type: ApplicationFiled: January 13, 2012Publication date: May 3, 2012Inventors: Teppei SHINNO, Yoshifumi Takahara
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Publication number: 20090325205Abstract: A biosensor 1 comprises a cavity 17 for holding a sample, an electrode system 14 for measuring the sample concentration in the cavity 17, and a thermocouple 16 for obtaining temperature information during measurement. A measurement device 2 comprises a reference temperature junction sensor 33 or an environmental temperature sensor 22 for measuring the temperature of reference temperature junctions 42 and 43 of the thermocouple. A temperature compensation step S9 involves measuring the temperature difference between a measuring junction 41 and a reference temperature junctions 42 and 43 of the thermocouple 16, specifying the temperature of a reference temperature junction, thereby using these temperature information as the temperature of a measurement component 18 and performing accurate temperature compensation from the measuring junction temperature information and the environmental temperature information with respect to the measured values.Type: ApplicationFiled: June 16, 2009Publication date: December 31, 2009Inventors: Takaaki Fujii, Yoshifumi Takahara, Noriyoshi Terashima
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Publication number: 20090321257Abstract: A biosensor that detects a target substance contained in a liquid sample has an insulating base plate including a recess formed in a portion that is thinner than the surrounding part, a working electrode and a counter electrode, at least one of which is disposed in the recess, and a reaction reagent that is disposed in the recess and reacts with a specific substance in the liquid sample.Type: ApplicationFiled: June 24, 2009Publication date: December 31, 2009Inventors: Yoshifumi TAKAHARA, Noriyoshi TERASHIMA, Takaaki FUJII
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Publication number: 20090236237Abstract: A liquid sample measurement apparatus of the present invention is provided with a timer (122) for measuring the time from when a biosensor (30) is attached to a liquid sample measurement device (110a) which measures the concentration of a specific component in a liquid sample that is applied to the biosensor (30) to when the liquid sample is applied to the biosensor (30), and correction based on the time measured by the timer (122) is performed to the measurement result of the concentration of the specific component in the liquid sample that is applied to the biosensor (30). Thereby, the measurement precision can be enhanced with utilizing the correction algorithm in which the ambient temperature and the temperature of the biosensor itself are considered.Type: ApplicationFiled: July 4, 2007Publication date: September 24, 2009Inventors: Teppei Shinno, Yoshifumi Takahara
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Publication number: 20090134023Abstract: In a biosensor of the present invention, BSA is contained in a reagent layer including a reagent which reacts specifically with glucose, and the glucose concentration in whole blood as a sample solution is electrochemically measured. When the sensor response characteristics when whole blood is used as the sample solution are measured, the influence by hematocrit to the sensor response characteristics is reduced according to the additive amount of BSA when the hematocrit value is in the range of 25% and below, while no BSA addition effect is recognized in the sensor response characteristics when the hematocrit value is in the range of 25 to 65%. Thereby, the influences by hematocrit and temperature can be reduced, and thus highly precise measurement can be performed.Type: ApplicationFiled: April 19, 2007Publication date: May 28, 2009Inventors: Junko Nakayama, Yoshifumi Takahara, Eriko Yamanishi, Yoshihiro Itoh