Patents by Inventor Yoshifumi Takahara

Yoshifumi Takahara has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11959872
    Abstract: The present invention provides a method for accurately measuring a blood component despite uneven distribution of blood introduced into a capillary. The measurement method according to the present invention is characterized in that a plurality of electrode systems for measuring the hematocrit are provided in a capillary of a biosensor to measure the hematocrit at different positions in the capillary. By measuring the hematocrit at the plurality of positions in the capillary as described above, the hematocrit can be measured mom accurately despite uneven distribution of blood introduced into the capillary.
    Type: Grant
    Filed: March 1, 2019
    Date of Patent: April 16, 2024
    Assignee: PHC Holdings Corporation
    Inventors: Masaki Fujiwara, Yoshifumi Takahara, Takaaki Fujii, Setsuko Yano, Fuminori Kutsuna
  • Patent number: 11639912
    Abstract: A reagent layer of a sensor contains as a mediator a quinone compound having a hydrophilic functional group, phenanthrenequinone, and/or a phenanthrenequinone derivative. The quinone compound has a lower redox potential than a conventional mediator, so interfering substances have less effect on detection results with this sensor.
    Type: Grant
    Filed: July 23, 2020
    Date of Patent: May 2, 2023
    Assignee: PHC HOLDINGS CORPORATION
    Inventors: Yoshifumi Takahara, Takahiro Nakaminami, Shin Ikeda
  • Patent number: 11467118
    Abstract: The present invention provides a method for accurately measuring a blood component despite uneven distribution of blood introduced into a capillary. The measurement method according to the present invention is characterized in that a plurality of electrode systems for measuring the hematocrit are provided in a capillary of a biosensor to measure the hematocrit at different positions in the capillary. By measuring the hematocrit at the plurality of positions in the capillary as described above, the hematocrit can be measured more accurately despite uneven distribution of blood introduced into the capillary.
    Type: Grant
    Filed: August 3, 2018
    Date of Patent: October 11, 2022
    Assignee: PHC Holdings Corporation
    Inventors: Masaki Fujiwara, Yoshifumi Takahara, Takaaki Fujii, Junko Nakayama, Setsuko Yano, Fuminori Kutsuna
  • Publication number: 20210010969
    Abstract: The present invention provides a method for accurately measuring a blood component despite uneven distribution of blood introduced into a capillary. The measurement method according to the present invention is characterized in that a plurality of electrode systems for measuring the hematocrit are provided in a capillary of a biosensor to measure the hematocrit at different positions in the capillary. By measuring the hematocrit at the plurality of positions in the capillary as described above, the hematocrit can be measured mom accurately despite uneven distribution of blood introduced into the capillary.
    Type: Application
    Filed: March 1, 2019
    Publication date: January 14, 2021
    Inventors: Masaki FUJIWARA, Yoshifumi TAKAHARA, Takaaki FUJII, Setsuko YANO, Fuminori KUTSUNA
  • Publication number: 20200371060
    Abstract: The present invention provides a method for accurately measuring a blood component despite uneven distribution of blood introduced into a capillary. The measurement method according to the present invention is characterized in that a plurality of electrode systems for measuring the hematocrit are provided in a capillary of a biosensor to measure the hematocrit at different positions in the capillary. By measuring the hematocrit at the plurality of positions in the capillary as described above, the hematocrit can be measured more accurately despite uneven distribution of blood introduced into the capillary.
    Type: Application
    Filed: August 3, 2018
    Publication date: November 26, 2020
    Inventors: Masaki FUJIWARA, Yoshifumi TAKAHARA, Takaaki FUJII, Junko NAKAYAMA, Setsuko YANO, Fuminori KUTSUNA
  • Publication number: 20200348255
    Abstract: A reagent layer of a sensor contains as a mediator a quinone compound having a hydrophilic functional group, phenanthrenequinone, and/or a phenanthrenequinone derivative. The quinone compound has a lower redox potential than a conventional mediator, so interfering substances have less effect on detection results with this sensor.
    Type: Application
    Filed: July 23, 2020
    Publication date: November 5, 2020
    Inventors: Yoshifumi TAKAHARA, Takahiro NAKAMINAMI, Shin IKEDA
  • Patent number: 10761044
    Abstract: A reagent layer of a sensor contains as a mediator a quinone compound having a hydrophilic functional group, phenanthrenequinone, and/or a phenanthrenequinone derivative. The quinone compound has a lower redox potential than a conventional mediator, so interfering substances have less effect on detection results with this sensor.
    Type: Grant
    Filed: November 10, 2015
    Date of Patent: September 1, 2020
    Assignee: PHC HOLDINGS CORPORATION
    Inventors: Yoshifumi Takahara, Takahiro Nakaminami, Shin Ikeda
  • Publication number: 20160061764
    Abstract: A reagent layer of a sensor contains as a mediator a quinone compound having a hydrophilic functional group, phenanthrenequinone, and/or a phenanthrenequinone derivative. The quinone compound has a lower redox potential than a conventional mediator, so interfering substances have less effect on detection results with this sensor.
    Type: Application
    Filed: November 10, 2015
    Publication date: March 3, 2016
    Inventors: Yoshifumi TAKAHARA, Takahiro NAKAMINAMI, Shin IKEDA
  • Patent number: 9212380
    Abstract: A reagent layer of a sensor contains as a mediator a quinone compound having a hydrophilic functional group, phenanthrenequinone, and/or a phenanthrenequinone derivative. The quinone compound has a lower redox potential than a conventional mediator, so interfering substances have less effect on detection results with this sensor.
    Type: Grant
    Filed: August 30, 2010
    Date of Patent: December 15, 2015
    Assignee: PANASONIC HEALTHCARE HOLDINGS CO., LTD.
    Inventors: Yoshifumi Takahara, Takahiro Nakaminami, Shin Ikeda
  • Patent number: 9046479
    Abstract: A biosensor detects a target substance contained in a liquid sample and includes an insulating base plate having a recess formed in a portion that is thinner than the surrounding part, a working electrode and a counter electrode, at least one of which is disposed in the recess. A reaction reagent is disposed in the recess and reacts with a specific substance in the liquid sample.
    Type: Grant
    Filed: June 24, 2009
    Date of Patent: June 2, 2015
    Assignee: PANASONIC HEALTHCARE HOLDINGS CO., LTD.
    Inventors: Yoshifumi Takahara, Noriyoshi Terashima, Takaaki Fujii
  • Patent number: 8845966
    Abstract: The measurement device comprises a sensor holder to which is removable to a biosensor. The sensor holder has measurement-use connection terminals that are in contact with the electrode system in the biosensor and are used to take off signals required for measuring the specific component, and thermocouple-use connection terminals that are in contact with the thermocouple in the biosensor and are used to take off the thermoelectromotive force signals.
    Type: Grant
    Filed: December 7, 2012
    Date of Patent: September 30, 2014
    Assignee: Panasonic Corporation
    Inventors: Takaaki Fujii, Yoshifumi Takahara, Noriyoshi Terashima
  • Patent number: 8349259
    Abstract: A biosensor includes a cavity for holding a sample, an electrode system for measuring the sample concentration in the cavity, and a thermocouple for obtaining temperature information during measurement. A measurement device includes a reference temperature junction sensor or an environmental temperature sensor for measuring the temperature of reference temperature junctions of the thermocouple. A temperature compensation measures the temperature difference between a measuring junction and a reference temperature junctions of the thermocouple, and specifies the temperature of a reference temperature junction, thereby using the temperature information as the temperature of a measurement component and performing accurate temperature compensation from the measuring junction temperature information and the environmental temperature information with respect to the measured values.
    Type: Grant
    Filed: June 16, 2009
    Date of Patent: January 8, 2013
    Assignee: Panasonic Corporation
    Inventors: Takaaki Fujii, Yoshifumi Takahara, Noriyoshi Terashima
  • Patent number: 8287704
    Abstract: A liquid sample measurement apparatus of the present invention is provided with a timer for measuring the time from when a biosensor is attached to a liquid sample measurement device which measures the concentration of a specific component in a liquid sample that is applied to the biosensor to when the liquid sample is applied to the biosensor, and correction based on the time measured by the timer is performed to the measurement result of the concentration of the specific component in the liquid sample that is applied to the biosensor. Thereby, the measurement precision can be enhanced with utilizing the correction algorithm in which the ambient temperature and the temperature of the biosensor itself are considered.
    Type: Grant
    Filed: January 13, 2012
    Date of Patent: October 16, 2012
    Assignee: Panasonic Corporation
    Inventors: Teppei Shinno, Yoshifumi Takahara
  • Patent number: 8287718
    Abstract: A liquid sample measurement apparatus of the present invention is provided with a timer for measuring the time from when a biosensor is attached to a liquid sample measurement device which measures the concentration of a specific component in a liquid sample that is applied to the biosensor to when the liquid sample is applied to the biosensor, and correction based on the time measured by the timer is performed to the measurement result of the concentration of the specific component in the liquid sample that is applied to the biosensor. Thereby, the measurement precision can be enhanced with utilizing the correction algorithm in which the ambient temperature and the temperature of the biosensor itself are considered.
    Type: Grant
    Filed: July 4, 2007
    Date of Patent: October 16, 2012
    Assignee: Panasonic Corporation
    Inventors: Teppei Shinno, Yoshifumi Takahara
  • Publication number: 20120152763
    Abstract: A reagent layer (4) of a sensor (1) contains as a mediator a quinone compound having a hydrophilic functional group, phenanthrenequinone, and/or a phenanthrenequinone derivative. The quinone compound has a lower redox potential than a conventional mediator, so interfering substances have less effect on detection results with this sensor 1.
    Type: Application
    Filed: August 30, 2010
    Publication date: June 21, 2012
    Inventors: Yoshifumi Takahara, Takahiro Nakaminami, Shin Ikeda
  • Publication number: 20120103806
    Abstract: A liquid sample measurement apparatus of the present invention is provided with a timer (122) for measuring the time from when a biosensor (30) is attached to a liquid sample measurement device (110a) which measures the concentration of a specific component in a liquid sample that is applied to the biosensor (30) to when the liquid sample is applied to the biosensor (30), and correction based on the time measured by the timer (122) is performed to the measurement result of the concentration of the specific component in the liquid sample that is applied to the biosensor (30). Thereby, the measurement precision can be enhanced with utilizing the correction algorithm in which the ambient temperature and the temperature of the biosensor itself are considered.
    Type: Application
    Filed: January 13, 2012
    Publication date: May 3, 2012
    Inventors: Teppei SHINNO, Yoshifumi Takahara
  • Publication number: 20090325205
    Abstract: A biosensor 1 comprises a cavity 17 for holding a sample, an electrode system 14 for measuring the sample concentration in the cavity 17, and a thermocouple 16 for obtaining temperature information during measurement. A measurement device 2 comprises a reference temperature junction sensor 33 or an environmental temperature sensor 22 for measuring the temperature of reference temperature junctions 42 and 43 of the thermocouple. A temperature compensation step S9 involves measuring the temperature difference between a measuring junction 41 and a reference temperature junctions 42 and 43 of the thermocouple 16, specifying the temperature of a reference temperature junction, thereby using these temperature information as the temperature of a measurement component 18 and performing accurate temperature compensation from the measuring junction temperature information and the environmental temperature information with respect to the measured values.
    Type: Application
    Filed: June 16, 2009
    Publication date: December 31, 2009
    Inventors: Takaaki Fujii, Yoshifumi Takahara, Noriyoshi Terashima
  • Publication number: 20090321257
    Abstract: A biosensor that detects a target substance contained in a liquid sample has an insulating base plate including a recess formed in a portion that is thinner than the surrounding part, a working electrode and a counter electrode, at least one of which is disposed in the recess, and a reaction reagent that is disposed in the recess and reacts with a specific substance in the liquid sample.
    Type: Application
    Filed: June 24, 2009
    Publication date: December 31, 2009
    Inventors: Yoshifumi TAKAHARA, Noriyoshi TERASHIMA, Takaaki FUJII
  • Publication number: 20090236237
    Abstract: A liquid sample measurement apparatus of the present invention is provided with a timer (122) for measuring the time from when a biosensor (30) is attached to a liquid sample measurement device (110a) which measures the concentration of a specific component in a liquid sample that is applied to the biosensor (30) to when the liquid sample is applied to the biosensor (30), and correction based on the time measured by the timer (122) is performed to the measurement result of the concentration of the specific component in the liquid sample that is applied to the biosensor (30). Thereby, the measurement precision can be enhanced with utilizing the correction algorithm in which the ambient temperature and the temperature of the biosensor itself are considered.
    Type: Application
    Filed: July 4, 2007
    Publication date: September 24, 2009
    Inventors: Teppei Shinno, Yoshifumi Takahara
  • Publication number: 20090134023
    Abstract: In a biosensor of the present invention, BSA is contained in a reagent layer including a reagent which reacts specifically with glucose, and the glucose concentration in whole blood as a sample solution is electrochemically measured. When the sensor response characteristics when whole blood is used as the sample solution are measured, the influence by hematocrit to the sensor response characteristics is reduced according to the additive amount of BSA when the hematocrit value is in the range of 25% and below, while no BSA addition effect is recognized in the sensor response characteristics when the hematocrit value is in the range of 25 to 65%. Thereby, the influences by hematocrit and temperature can be reduced, and thus highly precise measurement can be performed.
    Type: Application
    Filed: April 19, 2007
    Publication date: May 28, 2009
    Inventors: Junko Nakayama, Yoshifumi Takahara, Eriko Yamanishi, Yoshihiro Itoh