Abstract: An object is to provide a novel medical use of adipose tissue-derived mesenchymal stem cells. It was discovered that adipose tissue-derived mesenchymal stem cells (ASC) promote improvement of erectile dysfunction and recovery of the urge to urinate (improvement of sensory disorders of the lower urinary tract). On the basis of the discovery, a cell preparation containing adipose tissue-derived mesenchymal stem cells, which is effective to erectile dysfunction or sensory disorders of the lower urinary tract, is provided. In one embodiment, adipose tissue-derived mesenchymal stem cells and body fat are used in combination.

Abstract: An object is to provide a novel medical use of adipose tissue-derived mesenchymal stem cells. It was discovered that adipose tissue-derived mesenchymal stem cells (ASC) promote improvement of erectile dysfunction and recovery of the urge to urinate (improvement of sensory disorders of the lower urinary tract). On the basis of the discovery, a cell preparation containing adipose tissue-derived mesenchymal stem cells, which is effective to erectile dysfunction or sensory disorders of the lower urinary tract, is provided. In one embodiment, adipose tissue-derived mesenchymal stem cells and body fat are used in combination.

Abstract: An object is to provide a novel medical use of adipose tissue-derived mesenchymal stem cells. It was discovered that adipose tissue-derived mesenchymal stem cells (ASC) promote improvement of erectile dysfunction and recovery of the urge to urinate (improvement of sensory disorders of the lower urinary tract). On the basis of the discovery, a cell preparation containing adipose tissue-derived mesenchymal stem cells, which is effective to erectile dysfunction or sensory disorders of the lower urinary tract, is provided. In one embodiment, adipose tissue-derived mesenchymal stem cells and body fat are used in combination.

Abstract: A method for controlling an electroporation apparatus for use in an animal such as human and a non-human animal, the method comprising a step of applying a voltage to an electrode of the electroporation apparatus placed in/on a biological sample of the animal in the presence of a nucleic acid construct capable of inhibiting the expression of a gene in the animal. In this manner, a nucleic acid construct can be introduced into a cell of a living body with good efficiency.

Abstract: Provided is the excellent prevention or treatment of a vascular occlusive disease such as vascular restenosis. A pharmaceutical composition for a obstructive vascular disease comprising a nucleic acid construct capable of inhibiting the expression of a midkine gene through RNA interference and a collagen molecule. The use of the nucleic acid construct capable of inhibiting the expression of an MK protein through RNA interference in the presence of the collagen molecule can provide an excellent inhibitory effect on the thickened vascular intima.