Abstract: The present invention provides a drug for at least one of prevention and treatment of cardiac failure capable of suppressing cardiac depression and the onset of cardiac failure in ventricular remodeling, and a method for screening the drug. The drug for at least one of prevention and treatment of cardiac failure of the present invention contains a compound that inhibits a functional expression of ASK1 protein in a cardiomyocyte as an active ingredient, and a method for screening a drug for at least one of prevention and treatment of cardiac failure of the present invention includes selecting a medicinal component for at least one of prevention and treatment of cardiac failure from a drug candidate compound by using inhibition of a functional expression of ASK1 protein as an indication. As shown in FIG.

Abstract: A sewing machine control device performs a closed loop control of an induction motor without using an encoder for detecting the motor speed. The control device includes an inverter for driving the induction motor, and controls the inverter output so that the actual speed of the motor is brought into coincidence with a target speed instructed from a speed instruction device. When the control device executes the inverter control, it uses not only the target speed fed from the speed instruction device but also a detection signal generated from a needle position detector that represents the position of a needle bar and the moving speed thereof.

Abstract: A sewing system includes a plurality of sewing machines and a managing apparatus for managing sewing operations of the sewing machines. The managing apparatus determines a type of a work to be sewn by each of the sewing machines and sewing steps for such work, and supplies an identification code thereof to the sewing machines. A controller of the sewing machine reads out sewing data corresponding to the identification code from sewing data storage, and controls the sewing machine in accordance with the sewing data.

Abstract: A sewing machine including a mercury switch for detecting tilt of the sewing machine. When the tilt of the sewing machine is detected by the mercury switch, a machine motor of the sewing machine is inhibited from being driven. Accordingly, even if a foot switch for driving the machine motor is depressed under the tilted condition of the sewing machine, the machine motor is not driven, thereby improving the safety of the machine. Furthermore, when the sewing machine is tilted during driving of the machine motor, the inhibition of drive of the machine motor is canceled, and a driving speed of the machine motor is set to a low speed. Under this condition, an operator can easily adjust a fabric feeding device, a thread cutting device and a rotating hook.

Abstract: A process for producing .alpha.-olefin polymers is proposed wherein the catalyst prepared and used therein is superior in the shelf stability and heat stability. The process comprises reacting TiCl.sub.4 with a reaction product (I) of an organoaluminum compound with an electron donor to obtain a solid product (II), which is then subjected to polymerization treatment with an .alpha.-olefin, and further reacted with an electron donor and an electron acceptor to obtain a solid product (III), which is then combined with an organoaluminum compound, to obtain a catalyst, in the presence of which .alpha.-olefin(s) are polymerized. The catalyst can be further preactivated with an .alpha.-olefin in advance of its use for the polymerization.

Abstract: A process for producing highly crystalline .alpha.-olefin polymers of good particle form with high yield is provided, which comprises polymerizing .alpha.-olefin in the presence of a preactivated catalyst obtained by reacting a reaction product (I) of organoaluminum compound (A.sub.1) with electron donor (B.sub.1), with TiCl.sub.4 to obtain a solid product (II); further reacting (II) with electron donor (B.sub.2) and electron acceptor to obtain a solid product (III); during or/and after the reaction step for obtaining (II) or/and during or/and after the reaction step for obtaining (III), subjecting (II) or (III), to polymerization treatment with .alpha.-olefin; and combining the resulting final solid product with organo-aluminum compound (A.sub.2) and a reaction product (G) of organo-aluminum compound (A.sub.3) with electron donor (B.sub.3) to obtain a preactivated catalyst; and preferably, in this combination, further subjecting a part or the total of the catalyst to polymerization treatment with .alpha.

Abstract: A process for producing .alpha.-olefin polymers characterized by employing an organomagnesium compound in the preparation of a preactivated catalyst therefor is provided. The resulting polymers have particularly a higher rigidity in addition to various superior properties. The process comprises reacting a trivalent metal halide with a divalent metal compound to obtain a solid product (I); reacting this product with an organomagnesium compound, an electron donor (ED) and an electron acceptor (EA), once to 10 times, and at that time, using TiCl.sub.4 at least once as the (EA) to obtain a solid product (II); combining this product with an organoaluminum compound (OAl) and an (ED), and at that time, subjecting a combination of (II) and (OAl) or that of (II), (OAl) and (ED) to polymerization treatment with an .alpha.-olefin, and in the case of the former combination, further adding (ED), to obtain a preactivated catalyst; and polymerizing .alpha.-olefin(s) in the presence of this catalyst.

Abstract: A process for producing .alpha.-olefins is provided which comprises:milling (A) a trivalent metal halide together with (B) a divalent metal compound, in a specified ratio of (A) to (B), and reacting them to obtain a solid product (I);reacting with this product (I), (C) an electron donor and (D) an electron acceptor, (C) and (D) being respectively reacted once or more up to ten times, and TiCl.sub.4 being employed as the electron acceptor at least once, to obtain a solid product (II);combining with this product (II), (E) a trialkylaluminum and (G) a reaction product of an electron donor with an electron acceptor, and in this combination, subjecting a part or the whole of the catalyst components (product (II), (E) and (G)) to polymerization treatment by reacting (F) an .alpha.-olefin at least in the presence of the product (II) and trialkylaluminum, to obtain a preliminarily activated catalyst; andpolymerizing an .alpha.-olefin in the presence of this catalyst.

Abstract: A control system for a sewing machine includes at least an impulse generating circuit and a counter means connected thereto. A shift register having at least four bits and a mode selecting circuit connected thereto is provided. A circuit for feeding the work material or fabric forwards, a circuit for feeding the work material backwards, and a circuit for resetting these circuits are provided. The system is:(1) capable of selecting, in advance, the number of stitches in a single forward and backward reciprocal non-ravel seaming;(2) capable of doing a desired number of the repeated non-ravel seaming on a certain place (repeated reciprocal non-ravel seaming mode); and(3) capable of free selecting between the conventional non-ravel seaming mode and the above-mentioned repeated non-ravel seaming mode (the free mode selection).

Abstract: An improved speed controlling system for an electric motor, mainly used in a sewing machine includes a motor connected to a power supply, a speed controlling circuit or circuits for operating the motor at variably controlled speeds, and an electrical braking circuit or circuits for braking the motor upon receiving deceleration command from the speed controlling circuit(s) to transfer the motor from a high speed running state to a low speed running one. Electromechanical braking means are provided for acting on the motor, during at least a part of the braking period, the braking means being controlled by the electrical braking circuit(s). A low speed setting circuit is disposed in the speed controlling circuit(s) for maintaining the low speed running state caused by the electromechanical braking means and the electrical braking circuit(s).