Patents by Inventor Yoshiharu Itoh

Yoshiharu Itoh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240105349
    Abstract: A nuclear fusion system comprises: a muon generation unit to generate negative muons including electron and positron accelerators for generating electron and positron beams; a gas supply unit to supply to circulate gaseous deuterium or gaseous deuterium-tritium mixture as raw material gas; a Laval nozzle to accelerate the raw material gas to supersonic velocity; and a shock wave cone connected to the Laval nozzle to introduce the raw material gas accelerated to supersonic velocity to generate an oblique shock wave, the raw material gas accelerated to supersonic velocity being introduced into the shock wave cone to generate the oblique shock wave, the oblique shock wave being decelerated to create a high-density gas target in an in-flight manner, the muons generated as a result of causing electrons and positrons to collide with each other being introduced into the high-density gas target thereby to cause a muon-catalyzed nuclear fusion reaction to occur.
    Type: Application
    Filed: October 24, 2023
    Publication date: March 28, 2024
    Applicant: CHUBU UNIVERSITY EDUCATIONAL FOUNDATION
    Inventors: Shinji OKADA, Motoyasu SATO, Atsuo IIYOSHI, Kimitaka ITOH, Takashi MUTOH, Norimasa YAMAMOTO, Yoshiharu TANAHASHI
  • Publication number: 20230190730
    Abstract: An anti-HIV agent containing, as an active ingredient, ex, 4-oxoquinoline compound represented by the following formula [I] wherein each symbol is as defined in the specification, or a pharmaceutically acceptable salt thereof. The compound of the present invention has HIV integrase inhibitory action and is useful as an anti-HIV agent for the prophylaxis or therapy of AIDS. Moreover, by a combined use with other anti-HIV agents such as protease inhibitors, reverse transcriptase inhibitors and the like, the compound can become a more effective anti-HIV agent. Since the compound has high inhibitory activity specific for integrases, it can provide a safe pharmaceutical agent with a fewer side effects for human.
    Type: Application
    Filed: May 13, 2022
    Publication date: June 22, 2023
    Applicant: Japan Tobacco Inc.
    Inventors: Motohide Satoh, Hiroshi Kawakami, Yoshiharu Itoh, Hisashi Shinkai, Takahisa Motomura, Hisateru Aramaki, Yuji Matsuzaki, Wataru Watanabe, Shuichi Wamaki
  • Patent number: 10967115
    Abstract: Provided are a toxin separator and the like which are capable of selectively separating toxin present in a biological fluid by binding to protein, from the toxin and the protein. The toxin separator of the present invention also includes activated carbon of which a pore volume of pores having a pore diameter from 1.4 to 35 nm as measured by a nitrogen adsorption method is 0.06 cm3/g or greater.
    Type: Grant
    Filed: January 10, 2019
    Date of Patent: April 6, 2021
    Assignee: Kureha Corporation
    Inventors: Makoto Imaji, Kaori Kikuchi, Yoshiharu Itoh
  • Publication number: 20210001034
    Abstract: Provided are a toxin separator and the like which are capable of selectively separating toxin present in a biological fluid by binding to protein, from the toxin and the protein. The toxin separator of the present invention also includes activated carbon of which a pore volume of pores having a pore diameter from 1.4 to 35 nm as measured by a nitrogen adsorption method is 0.06 cm3/g or greater.
    Type: Application
    Filed: January 10, 2019
    Publication date: January 7, 2021
    Applicant: Kureha Corporation
    Inventors: Makoto IMAJI, Kaori KIKUCHI, Yoshiharu ITOH
  • Publication number: 20200101061
    Abstract: An anti-HIV agent containing, as an active ingredient, a 4-oxoquinoline compound represented by the following formula [I] wherein each symbol is as defined in the specification, or a pharmaceutically acceptable salt thereof. The compound of the present invention has HIV integrase inhibitory action and is useful as an anti-HIV agent for the prophylaxis or therapy of AIDS. Moreover, by a combined use with other anti-HIV agents such as protease inhibitors, reverse transcriptase inhibitors and the like, the compound can become a more effective anti-HIV agent. Since the compound has high inhibitory activity specific for integrases, it can provide a safe pharmaceutical agent with a fewer side effects for human.
    Type: Application
    Filed: May 10, 2019
    Publication date: April 2, 2020
    Applicant: Japan Tobacco Inc.
    Inventors: Motohide Satoh, Hiroshi Kawakami, Yoshiharu Itoh, Hisashi Shinkai, Takahisa Motomura, Hisateru Aramaki, Yuji Matsuzaki, Wataru Watanabe, Shuichi Wamaki
  • Publication number: 20150355171
    Abstract: An object of the present invention is to provide a competitive EIA method capable of quantitatively measuring indoxyl sulfate in blood. The problem described above can be solved by an indoxyl sulfate measurement method based on a competitive method comprising: (1) a step in which albumin in a specimen is pretreated; (2) a specimen-antibody reaction step in which the pretreated specimen and anti-indoxyl sulfate antibodies are brought into contact with each other in the substantial absence of exogenous mammalian albumin; (3) an immobilized IS-antibody reaction step in which the specimen-antibody reaction solution is brought into contact, in the substantial absence of exogenous mammalian albumin, with an immobilized insoluble support in which indoxyl sulfate is immobilized and then blocked with a buffer solution containing substantially no mammalian albumin; and (4) a step in which anti-indoxyl sulfate antibodies which have bonded to the immobilized insoluble support are detected.
    Type: Application
    Filed: February 17, 2014
    Publication date: December 10, 2015
    Inventors: Hirotaka Hoshi, Kaori Kikuchi, Yoshiharu Itoh, Ayano Konagai
  • Patent number: 9086808
    Abstract: A storage apparatus includes a memory that stores a job management information that registers a write job corresponding to a write command upon receiving the write command from other apparatus, a cache memory that stores data designated as target data by the write command, a storage drive that records the data stored in the cache memory to a storage medium based on the write job registered in the job management information, and a controller that controls a timing to output to the other apparatus a completion report of the write command based on a load condition of the storage device related to an accumulation count of write job acquired from the job management information.
    Type: Grant
    Filed: June 19, 2012
    Date of Patent: July 21, 2015
    Assignee: FUJITSU LIMITED
    Inventor: Yoshiharu Itoh
  • Publication number: 20150174117
    Abstract: An anti-HIV agent containing, as an active ingredient, a 4-oxoquinoline compound represented by the following formula [I] wherein each symbol is as defined in the specification, or a pharmaceutically acceptable salt thereof. The compound of the present invention has HIV integrase inhibitory action and is useful as an anti-HIV agent for the prophylaxis or therapy of AIDS. Moreover, by a combined use with other anti-HIV agents such as protease inhibitors, reverse transcriptase inhibitors and the like, the compound can become a more effective anti-HIV agent. Since the compound has high inhibitory activity specific for integrases, it can provide a safe pharmaceutical agent with a fewer side effects for human.
    Type: Application
    Filed: June 10, 2014
    Publication date: June 25, 2015
    Inventors: Motohide SATOH, Hiroshi Kawakami, Yoshiharu Itoh, Hisashi Shinkai, Takahisa Motomura, Hisateru Aramaki, Yuji Matsuzaki, Wataru Watanabe, Shuichi Wamaki
  • Publication number: 20140365727
    Abstract: A storage control device includes a processor. The processor is configured to receive commands requesting access to a first storage. The processor is configured to detect, among the received commands, a monitoring command requesting access for monitoring to the first storage. The processor is configured to restrict access to the first storage in response to the detected monitoring command.
    Type: Application
    Filed: April 14, 2014
    Publication date: December 11, 2014
    Applicant: FUJITSU LIMITED
    Inventors: Hidekazu KAWANO, Hajime Watanabe, Jun Ishizaki, Hiroshi Chiba, Nobukazu Kirigaya, Yoshiharu Itoh, Hiroshi Ichikawa
  • Publication number: 20130172344
    Abstract: An anti-HIV agent containing, as an active ingredient, a 4-oxoquinoline compound represented by the following formula [I] wherein each symbol is as defined in the specification, or a pharmaceutically acceptable salt thereof. The compound of the present invention has HIV integrase inhibitory action and is useful as an anti-HIV agent for the prophylaxis or therapy of AIDS. Moreover, by a combined use with other anti-HIV agents such as protease inhibitors, reverse transcriptase inhibitors and the like, the compound can become a more effective anti-HIV agent. Since the compound has high inhibitory activity specific for integrases, it can provide a safe pharmaceutical agent with a fewer side effects for human.
    Type: Application
    Filed: June 20, 2012
    Publication date: July 4, 2013
    Inventors: Motohide SATOH, Hiroshi Kawakami, Yoshiharu Itoh, Hisashi Shinkai, Takahisa Motomura, Hisateru Aramaki, Yuji Matsuzaki, Wataru Watanabe, Shuichi Wamaki
  • Patent number: 8458391
    Abstract: A library apparatus includes a medium name storage unit that stores medium name conversion information in which a virtual medium name specifying a storage medium in a read/write request from a host is related to a real medium name specifying the storage medium in the library apparatus, a conveying mechanism unit that conveys the storage medium, a drive that reads/writes data from/to the storage medium conveyed by the conveying mechanism unit in response to the received read/write request, a conversion unit that converts the virtual medium name included in the received read/write request to the real medium name on the basis of the medium name conversion information stored in the medium name storage unit, and a conveying mechanism control unit that controls the conveying mechanism unit to convey the storage medium having the real medium name converted by the conversion unit to the drive.
    Type: Grant
    Filed: March 1, 2011
    Date of Patent: June 4, 2013
    Assignee: Fujitsu Limited
    Inventor: Yoshiharu Itoh
  • Publication number: 20130031307
    Abstract: A storage apparatus includes a memory that stores a job management information that registers a write job corresponding to a write command upon receiving the write command from other apparatus, a cache memory that stores data designated as target data by the write command, a storage drive that records the data stored in the cache memory to a storage medium based on the write job registered in the job management information, and a controller that controls a timing to output to the other apparatus a completion report of the write command based on a load condition of the storage device related to an accumulation count of write job acquired from the job management information.
    Type: Application
    Filed: June 19, 2012
    Publication date: January 31, 2013
    Applicant: FUJITSU LIMITED
    Inventor: Yoshiharu Itoh
  • Patent number: 8232401
    Abstract: An anti-HIV agent containing, as an active ingredient, a 4-oxoquinoline compound represented by the following formula [I] wherein each symbol is as defined in the specification, or a pharmaceutically acceptable salt thereof. The compound of the present invention has HIV integrase inhibitory action and is useful as an anti-HIV agent for the prophylaxis or therapy of AIDS. Moreover, by a combined use with other anti-HIV agents such as protease inhibitors, reverse transcriptase inhibitors and the like, the compound can become a more effective anti-HIV agent. Since the compound has high inhibitory activity specific for integrases, it can provide a safe pharmaceutical agent with a fewer side effects for human.
    Type: Grant
    Filed: June 5, 2006
    Date of Patent: July 31, 2012
    Assignee: Japan Tobacco Inc.
    Inventors: Motohide Satoh, Hiroshi Kawakami, Yoshiharu Itoh, Hisashi Shinkai, Takahisa Motomura, Hisateru Aramaki, Yuji Matsuzaki, Wataru Watanabe, Shuichi Wamaki
  • Publication number: 20110238929
    Abstract: A library apparatus includes a medium name storage unit that stores medium name conversion information in which a virtual medium name specifying a storage medium in a read/write request from a host is related to a real medium name specifying the storage medium in the library apparatus, a conveying mechanism unit that conveys the storage medium, a drive that reads/writes data from/to the storage medium conveyed by the conveying mechanism unit in response to the received read/write request, a conversion unit that converts the virtual medium name included in the received read/write request to the real medium name on the basis of the medium name conversion information stored in the medium name storage unit, and a conveying mechanism control unit that controls the conveying mechanism unit to convey the storage medium having the real medium name converted by the conversion unit to the drive.
    Type: Application
    Filed: March 1, 2011
    Publication date: September 29, 2011
    Applicant: FUJITSU LIMITED
    Inventor: Yoshiharu ITOH
  • Patent number: 7176220
    Abstract: An anti-HIV agent containing, as an active ingredient, a 4-oxoquinoline compound represented by the following formula [I] wherein each symbol is as defined in the specification, or a pharmaceutically acceptable salt thereof. The compound of the present invention has HIV integrase inhibitory action and is useful as an anti-HIV agent for the prophylaxis or therapy of AIDS. Moreover, by a combined use with other anti-HIV agents such as protease inhibitors, reverse transcriptase inhibitors and the like, the compound can become a more effective anti-HIV agent. Since the compound has high inhibitory activity specific for integrases, it can provide a safe pharmaceutical agent with a fewer side effects for human.
    Type: Grant
    Filed: November 20, 2003
    Date of Patent: February 13, 2007
    Assignee: Japan Tobacco Inc.
    Inventors: Motohide Satoh, Hiroshi Kawakami, Yoshiharu Itoh, Hisashi Shinkai, Takahisa Motomura, Hisateru Aramaki, Yuji Matsuzaki, Wataru Watanabe, Shuichi Wamaki
  • Patent number: 7139147
    Abstract: A drive control apparatus receives an instruction from an upper unit, to mount a predetermined medium onto a predetermined drive unit. If a combination of the predetermined medium and the predetermined drive unit is determined as inappropriate, the drive control unit replies to the upper unit that the predetermined drive unit cannot be used. A combination of a medium and a drive is appropriate if both, the medium and the drive are suitable for any one of encrypted and unencrypted data.
    Type: Grant
    Filed: July 25, 2005
    Date of Patent: November 21, 2006
    Assignee: Fujitsu Limited
    Inventors: Mitsuru Yasue, Kinya Saito, Kenichi Utsumi, Reisuke Nakagawa, Hitomi Akiyama, Ichirou Sakuma, Hiroyasu Inagaki, Yoshiharu Itoh
  • Publication number: 20060215305
    Abstract: A drive control apparatus receives an instruction from an upper unit, to mount a predetermined medium onto a predetermined drive unit. If a combination of the predetermined medium and the predetermined drive unit is determined as inappropriate, the drive control unit replies to the upper unit that the predetermined drive unit cannot be used. A combination of a medium and a drive is appropriate if both, the medium and the drive are suitable for any one of encrypted and unencrypted data.
    Type: Application
    Filed: July 25, 2005
    Publication date: September 28, 2006
    Inventors: Mitsuru Yasue, Kinya Saito, Kenichi Utsumi, Reisuke Nakagawa, Hitomi Akiyama, Ichirou Sakuma, Hiroyasu Inagaki, Yoshiharu Itoh
  • Publication number: 20060217413
    Abstract: An anti-HIV agent containing, as an active ingredient, a 4-oxoquinoline compound represented by the following formula [I] wherein each symbol is as defined in the specification, or a pharmaceutically acceptable salt thereof. The compound of the present invention has HIV integrase inhibitory action and is useful as an anti-HIV agent for the prophylaxis or therapy of AIDS. Moreover, by a combined use with other anti-HIV agents such as protease inhibitors, reverse transcriptase inhibitors and the like, the compound can become a more effective anti-HIV agent. Since the compound has high inhibitory activity specific for integrases, it can provide a safe pharmaceutical agent with a fewer side effects for human.
    Type: Application
    Filed: June 5, 2006
    Publication date: September 28, 2006
    Inventors: Motohide Satoh, Hiroshi Kawakami, Yoshiharu Itoh, Hisashi Shinkai, Takahisa Motomura, Hisateru Aramaki, Yuji Matsuzaki, Wataru Watanabe, Shuichi Wamaki
  • Publication number: 20050239819
    Abstract: An anti-HIV agent containing, as an active ingredient, a 4-oxoquinoline compound represented by the following formula [I] wherein each symbol is as defined in the specification, or a pharmaceutically acceptable salt thereof. The compound of the present invention has HIV integrase inhibitory action and is useful as an anti-HIV agent for the prophylaxis or therapy of AIDS. Moreover, by a combined use with other anti-HIV agents such as protease inhibitors, reverse transcriptase inhibitors and the like, the compound can become a more effective anti-HIV agent. Since the compound has high inhibitory activity specific for integrases, it can provide a safe pharmaceutical agent with a fewer side effects for human.
    Type: Application
    Filed: November 20, 2003
    Publication date: October 27, 2005
    Inventors: Motohide Satoh, Hiroshi Kawakami, Yoshiharu Itoh, Hisashi Shinkai, Takahisa Motomura, Hisateru Aramaki, Yuji Matsuzaki, Wataru Watanabe, Shuichi Wamaki
  • Patent number: 4123835
    Abstract: A fuel pump has a cam shaft for actuating a pump element to deliver fuel under pressure to an engine. One end of the cam shaft protrudes outside of a pump housing, to which a coupling block is fixedly secured. At least two axially extending threaded holes are formed on the coupling block, and also at least two axially extending through holes are formed on a driving gear for engaging a ring gear of the engine. A head-less locking bolt is screwed into one of threaded holes until the front end thereof abut on the pump housing so that the coupling block is held at a proper position. Thereafter, the driving gear is mounted to the coupling block so that the rear end of the head-less bolt is inserted into one of the through holes and at the same time the driving gear engages with the ring gear of the engine in order to couple the fuel pump to the engine with a synchronous relationship.
    Type: Grant
    Filed: June 24, 1977
    Date of Patent: November 7, 1978
    Assignee: Nippondenso Co., Ltd.
    Inventors: Yoshiharu Itoh, Makoto Iwatsuki, Kazuhiro Suzuki, Tatuya Seko