Patents by Inventor Yoshiharu Oguchi

Yoshiharu Oguchi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5693610
    Abstract: A binding agent for a growth factor selected from the group consisting of transforming growth factor-.beta. (TGF-.beta.) and platelet-derived growth factor (PDGF), comprising a protein-bound polysaccharide which is obtained from a fungus belonging to Coriolus, and contains about 18 to 38% by weight of proteins, and a pharmaceutically acceptable carrier or diluent is disclosed.
    Type: Grant
    Filed: August 24, 1995
    Date of Patent: December 2, 1997
    Assignee: Kureha Chemical Industry Co., Ltd.
    Inventors: Kenichi Matsunaga, Yoshiharu Oguchi, Minoru Ohara
  • Patent number: 5089481
    Abstract: Disclosed herein are polysaccharides extracted from marine algae and an antiviral drug containing as active ingredient polysaccharides extracted from seaweeds.
    Type: Grant
    Filed: November 15, 1990
    Date of Patent: February 18, 1992
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Shigeaki Muto, Koichi Niimura, Minoru Oohara, Yoshiharu Oguchi, Kenichi Matsunaga, Kunitaka Hirose, Junji Kakuchi, Norifumi Sugita, Takao Furusho, Chikao Yoshikumi, Masaaki Takahashi
  • Patent number: 5008243
    Abstract: Disclosed herein is a pharmaceutical composition having antirheumatic activity, antithrombotic activity, analgetic activity, antipyretics activity, anti-hyperlipemic activity and anti-inflammatory activity and activities of reducing the level of blood sugar, raising the coronary blood flow, improving the capability of deformation of erythrocytes, reducing the blood pressure, ameliorating proteinuria and proteinemia and regulating production or metabolism of prostaglandins in a mammal in dosage unit form, which comprises a dosage effective to produce said activities of a glycoprotein having a molecular weight of 5000 to 300,000 as determined by ultracentrifugal method and about 18 to 38% by weight of proteins, produced by culturing a basidiomycetous fungal species belonging to the genus Coriolus, extracting the thus proliferated mycelia or fruit bodies with hot water or aqueous alkali solution and removing low molecular weight substances having a molecular weight of less than 5000 from the extract.
    Type: Grant
    Filed: December 16, 1988
    Date of Patent: April 16, 1991
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Masanori Ikuzawa, Yoshiharu Oguchi, Kenichi Matsunaga, Noriyuki Toyoda, Takao Furusho, Takayoshi Fujii, Chikao Yoshikumi
  • Patent number: 4985543
    Abstract: Disclosed herein are lectins extracted form a plant of the class Dicotyledoneae and an antiretoviral drug comprising as an active ingredient an effective amount of the lectins.
    Type: Grant
    Filed: June 17, 1988
    Date of Patent: January 15, 1991
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Norifumi Sugita, Koichi Niimura, Yoshiharu Oguchi, Kunitaka Hirose, Kenichi Matsunaga, Minoru Oohara, Shigeaki Muto, Junji Kakuchi, Takao Furusho, Chikao Yoshikumi, Masaaki Takahashi
  • Patent number: 4925662
    Abstract: Disclosed herein are an anti-tumor substance obtained by bonding an anti-tumor agent to human immunoglobulin, and a process for producing the same.
    Type: Grant
    Filed: January 14, 1988
    Date of Patent: May 15, 1990
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Yoshiharu Oguchi, Koichi Niimura, Takayoshi Fujii, Masahiko Fujii, Kenichi Matsunaga, Chikao Yoshikumi
  • Patent number: 4820689
    Abstract: Disclosed herein is a pharmaceutical composition having antirheumatic activity, antithrombotic activity, analgetic activity, antipyretic activity, anti-hyperlipemic activity and anti-inflammatory activity and activities of reducing the level of blood sugar, raising the coronary blood flow, improving the capability of deformation of erythrocytes, reducing the blood pressure, ameliorating proteinuria and proteinemia and regulating production or metabolism of prostaglandins in a mammal in dosage unit form, which comprises a dosage effective to produce said activities of a glycoprotein having a molecular weight of 5000 to 300000 as determined by ultracentrifugal method and about 18 to 38% by weight of proteins, produced by culturing a basidiomycetous fungal species belonging to the genus Coriolus, extracting the thus proliferated mycelia or fruit bodies with hot water or aqueous alkali solution and removing low molecular weight substances having a molecular weight of less than 5000 from the extract.
    Type: Grant
    Filed: August 22, 1986
    Date of Patent: April 11, 1989
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Masanori Ikuzawa, Yoshiharu Oguchi, Kenichi Matsunaga, Noriyuki Toyoda, Takao Furusho, Takayoshi Fujii, Chikao Yoshikumi
  • Patent number: 4783419
    Abstract: Disclosed herein is a method for examining cells, comprising subjecting the cells to an antigen-antibody reaction treatment, then measuring a pattern of the electrophoretic mobility of the cells and comparing the electrophoretic property of the cells under examination with the electrophoretic property of standard cells.
    Type: Grant
    Filed: March 21, 1985
    Date of Patent: November 8, 1988
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Haruhisa Hayashi, Yoshiharu Oguchi, Kenichi Matsunaga, Chikao Yoshikumi
  • Patent number: 4738843
    Abstract: Disclosed herein are an anti-tumor substance obtained by bonding an anti-tumor agent to human immunoglobulin, and a process for producing the same.
    Type: Grant
    Filed: January 20, 1987
    Date of Patent: April 19, 1988
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Yoshiharu Oguchi, Koichi Niimura, Takayoshi Fujii, Masahiko Fujii, Kenichi Matsunaga, Chikao Yoshikumi
  • Patent number: 4632743
    Abstract: Cells, particularly lymphocytes in peripheral blood or lymphatic tissues such as thymus, spleen and lymph node, are examined by measuring an electrophoretic property, such as a fraction of the number of the cells having an electrophoretic mobility within a predetermined range to the total number of the cells to be examined, with the aid of an automatic electrophoretic apparatus which is operated in a medium of the physiological conditions and by reversing the electric field, and comparing the obtained pattern of the electrophoretic property of the cells to be examined with the pattern of the electrophoretic property of normal host-cells, in order to diagnose cancer.
    Type: Grant
    Filed: April 25, 1984
    Date of Patent: December 30, 1986
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Chikao Yoshikumi, Kenichi Matsunaga, Haruhisa Hayashi, Yoshiharu Oguchi
  • Patent number: 4401592
    Abstract: Disclosed is a novel pharmaceutical composition having antitumor (anti-cancer) activity without causing pyrexia and anaphylaxis, formed by an amide bonding between an antibody obtained by the purification of the antibody to tumor (cancer) antigen via affinity-chromatography and an antitumor substance (anti-cancer drug).
    Type: Grant
    Filed: November 16, 1981
    Date of Patent: August 30, 1983
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Chikao Yoshikumi, Takayoshi Fujii, Masahiko Fujii, Kenichi Matsunaga, Yoshiharu Oguchi, Koichi Niimura
  • Patent number: 4315851
    Abstract: Disclosed is a novel pharmaceutical composition having antitumor activity without causing pyrexia and anaphylaxis formed by an amido bonding between an antibody obtained by the purification of the antibody to tumor antigen via affinity-chromatography and an antitumor substance.
    Type: Grant
    Filed: December 14, 1979
    Date of Patent: February 16, 1982
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Chikao Yoshikumi, Takayoshi Fujii, Masahiko Fujii, Kenichi Matsunaga, Yoshiharu Oguchi, Koichi Niimura