Abstract: The present disclosure provides novel pladienolide compounds, pharmaceutical compositions containing such compounds, and methods for using the compounds as therapeutic agents. These compounds may be useful in the treatment of cancers, particularly cancers in which agents that target the spliceosome and mutations therein are known to be useful. Also provided herein are methods of treating cancers by administering at least one compound disclosed herein and at least one additional therapy.

Abstract: An image forming apparatus includes a replacement time predicting circuit, a variation determining circuit, and a replacement time adjusting circuit. The replacement time predicting circuit periodically predicts, based on a consumption trend, a replacement time of a consumption article starting from a time when a replacement article is ordered, the replacement time being a time when a non-consumption amount of the consumption article is equal to or less than a specific replacement threshold. The variation determining circuit determines a variation of each later-predicted replacement time from a replacement time that is predicted when the replacement article is ordered, each later-predicted replacement time being predicted after the replacement article is ordered. The replacement time adjusting circuit, in response to the variation determined by the variation determining circuit, changes the consumption trend of the consumption article so as to reduce or eliminate the variation.

Abstract: A display apparatus includes a display, a function setting circuit, a switching control circuit, and a simple menu creation control circuit. The simple menu creation control circuit creates, when it is determined by the switching control circuit that a number of times of selection is greater than or equal to a set number or an elapsed time is greater than or equal to a set time, a first simple menu for use in display on the display, the first simple menu being obtained by eliminating, from the plurality of operation menu items, an operation menu item corresponding to a function whose number of times of selection by a user is greater than or equal to a set number.

Abstract: Provided are an image forming apparatus capable of setting a printing size of a margin by using a preview displayed in an enlarged manner, and a non-transitory computer-readable storage medium. When a pinch-in operation performed with respect to a particular region at a left end in a whole page preview displayed on a display section has been accepted, an MFP displays a left end preview in an enlarged manner to be larger in size than the particular region at the left end in the whole page preview. When a left-to-right swipe operation performed with respect to the displayed left end preview has been accepted, the MFP sets a size specified by the swipe operation as a printing size of a margin of a page as a target of the preview, and displays a whole page preview and a left end preview, both reflecting a margin having the set size.

Abstract: An image forming apparatus includes a storage portion, a preview image generating circuit, an output image generating circuit, a data information obtaining circuit, and a display circuit. The storage portion stores image data that is an output target. The preview image generating circuit generates a preview image from the image data based on an output setting. The output image generating circuit generates an output image from the image data based on the output setting. The data information obtaining circuit obtains data information from output image data of the output image, and discards the output image data from which the data information was obtained. The display circuit displays the data information together with the preview image.

Abstract: To provide an approval system associated with an approval workflow that identifies a signature document. A document management server for managing document data is connected with a client terminal (CLT) via an in-house LAN. Also, a seal to be affixed to a paper containing document specification information establishes a communication to the CLT. The seal reads the document specification information and user's fingerprint information and transmits the resulting pieces of information and impression information to the CLT. The document management server receives the document specification information, the fingerprint information and the impression information to confirm a coincidence between the received fingerprint and matching fingerprint and to confirm a coincidence between a set of the received document specification information and the received impression information and a set of matching document specification information and matching impression information, and to notify an approval situation to the CLT.

Abstract: A mobile terminal includes: a storage section storing pieces of schedule information indicating respective user's schedules in which planned activities are assigned to respective scheduled dates and times; an incoming contact detection section that detects an incoming contact on the mobile terminal; a date and time information acquisition section that acquires date and time information indicating a current date and time on detection of the incoming contact; a schedule information acquisition section that acquires a piece of schedule information at a scheduled date and time based on the acquired date and time information; an alert operation attribute determining section that determines from the acquired piece of schedule information an alert operation attribute with which the planned activity is associated; and an alert operation control processing section that controls an alert operation notifying the user of the incoming contact according to the determined alert operation attribute.

Abstract: A device management system includes an electronic device and a remote maintenance server. The electronic device displays an operation screen to a user. The remote maintenance server includes a transparent panel management portion that draws a guide image on a virtual transparent panel based on an operation of a service person performed on a service terminal device, and causes the electronic device to overlay and display the virtual transparent panel on the operation screen.

Abstract: An image forming apparatus includes a replacement time predicting circuit, a variation determining circuit, and a replacement time adjusting circuit. The replacement time predicting circuit periodically predicts, based on a consumption trend, a replacement time of a consumption article starting from a time when a replacement article is ordered, the replacement time being a time when a non-consumption amount of the consumption article is equal to or less than a specific replacement threshold. The variation determining circuit determines a variation of each later-predicted replacement time from a replacement time that is predicted when the replacement article is ordered, each later-predicted replacement time being predicted after the replacement article is ordered. The replacement time adjusting circuit, in response to the variation determined by the variation determining circuit, changes the consumption trend of the consumption article so as to reduce or eliminate the variation.

Abstract: An image forming apparatus includes a storage portion, a preview image generating circuit, an output image generating circuit, a data information obtaining circuit, and a display circuit. The storage portion stores image data that is an output target. The preview image generating circuit generates a preview image from the image data based on an output setting. The output image generating circuit generates an output image from the image data based on the output setting. The data information obtaining circuit obtains data information from output image data of the output image, and discards the output image data from which the data information was obtained. The display circuit displays the data information together with the preview image.

Abstract: A display apparatus includes a display, a function setting circuit, a switching control circuit, and a simple menu creation control circuit. The simple menu creation control circuit creates, when it is determined by the switching control circuit that a number of times of selection is greater than or equal to a set number or an elapsed time is greater than or equal to a set time, a first simple menu for use in display on the display, the first simple menu being obtained by eliminating, from the plurality of operation menu items, an operation menu item corresponding to a function whose number of times of selection by a user is greater than or equal to a set number.

Abstract: Provided are an image forming apparatus capable of setting a printing size of a margin by using a preview displayed in an enlarged manner, and a non-transitory computer-readable storage medium. When a pinch-in operation performed with respect to a particular region at a left end in a whole page preview displayed on a display section has been accepted, an MFP displays a left end preview in an enlarged manner to be larger in size than the particular region at the left end in the whole page preview. When a left-to-right swipe operation performed with respect to the displayed left end preview has been accepted, the MFP sets a size specified by the swipe operation as a printing size of a margin of a page as a target of the preview, and displays a whole page preview and a left end preview, both reflecting a margin having the set size.

Abstract: To provide an approval system associated with an approval workflow that identifies a signature document. A document management server for managing document data is connected with a client terminal (CLT) via an in-house LAN. Also, a seal to be affixed to a paper containing document specification information establishes a communication to the CLT. The seal reads the document specification information and user's fingerprint information and transmits the resulting pieces of information and impression information to the CLT. The document management server receives the document specification information, the fingerprint information and the impression information to confirm a coincidence between the received fingerprint and matching fingerprint and to confirm a coincidence between a set of the received document specification information and the received impression information and a set of matching document specification information and matching impression information, and to notify an approval situation to the CLT.

Abstract: A mobile terminal includes: a storage section storing pieces of schedule information indicating respective user's schedules in which planned activities are assigned to respective scheduled dates and times; an incoming contact detection section that detects an incoming contact on the mobile terminal; a date and time information acquisition section that acquires date and time information indicating a current date and time on detection of the incoming contact; a schedule information acquisition section that acquires a piece of schedule information at a scheduled date and time based on the acquired date and time information; an alert operation attribute determining section that determines from the acquired piece of schedule information an alert operation attribute with which the planned activity is associated; and an alert operation control processing section that controls an alert operation notifying the user of the incoming contact according to the determined alert operation attribute.

Abstract: An agent unit acquires apparatus status information that indicates a status of the electronic apparatus from an electronic apparatus. A remote maintenance server transmits an acquisition instruction of the apparatus status information to the agent unit and receives the apparatus status information from the agent unit if acquisition of the apparatus status information succeeded. The remote maintenance server (a) acquires operation schedule information on the electronic apparatus, (b) transmits an acquisition instruction of the apparatus status information to the agent unit, (c) registers a retransmission schedule of the acquisition instruction so as to transmit the acquisition instruction at a timing within an operation period of the electronic apparatus determined from the operation schedule if acquisition of the apparatus status information failed, and (d) transmits the acquisition instruction to the agent unit at the timing of the retransmission schedule.

Abstract: A device management system includes an electronic device and a remote maintenance server. The electronic device displays an operation screen to a user. The remote maintenance server includes a transparent panel management portion that draws a guide image on a virtual transparent panel based on an operation of a service person performed on a service terminal device, and causes the electronic device to overlay and display the virtual transparent panel on the operation screen.

Abstract: An agent unit acquires apparatus status information from an electronic apparatus. A remote maintenance server receives and stores the apparatus status information transmitted from the agent unit. The agent unit (a) issues a response request of whether transmission of the apparatus status information is permitted or denied to a user of the electronic apparatus when a transmission request of the apparatus status information is detected, (b1) transmits a notification that indicates that transmission of the apparatus status information is denied to the remote maintenance server without transmitting the apparatus status information if a response to the response request is received and the received response indicates that transmission of the apparatus status information is denied, and (b2) transmits the apparatus status information if a response to the response request is received and the received response indicates that transmission of the apparatus status information is permitted.

Abstract: An electronic apparatus includes: an operation panel configured to display a screen for a user and receive an operation by the user; a display control unit configured to control display of a screen on the operation panel; and an agent unit configured to control timings of starting and cancelling display of a message screen based on message data received from a remote maintenance server on a maintenance service provider side. The agent unit is further configured to generate reading confirmation data that indicates that a user read the message screen and transmit the reading confirmation data to the remote maintenance server if the operation panel receives an operation by the user for cancelling display of the message screen while the message screen is displayed on the operation panel.

Abstract: An agent unit acquires apparatus status information that indicates a status of the electronic apparatus from an electronic apparatus. A remote maintenance server transmits an acquisition instruction of the apparatus status information to the agent unit and receives the apparatus status information from the agent unit if acquisition of the apparatus status information succeeded. The remote maintenance server (a) acquires operation schedule information on the electronic apparatus, (b) transmits an acquisition instruction of the apparatus status information to the agent unit, (c) registers a retransmission schedule of the acquisition instruction so as to transmit the acquisition instruction at a timing within an operation period of the electronic apparatus determined from the operation schedule if acquisition of the apparatus status information failed, and (d) transmits the acquisition instruction to the agent unit at the timing of the retransmission schedule.

Abstract: An electronic apparatus includes: an operation panel configured to display a screen and receive an operation performed by a user; an agent unit configured to, upon receipt of message data from a remote maintenance server on a maintenance service provider side, provide an instruction to display a message screen based on the message data; and a display control unit configured to control the display of a screen on the operation panel and configured to, when the instruction to display the message screen is received while an operation screen is being displayed, display the message screen on the operation panel upon detection of an end of an operation of the operation panel performed by the user.