Patents by Inventor Yoshihiko FUJISAKI

Yoshihiko FUJISAKI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TREATMENT OF HER2-MUTATED CANCER BY ADMINISTERING ANTI-HER2 ANTIBODY-DRUG CONJUGATE
    Publication number: 20210205466
    Abstract: A therapeutic agent for HER2-mutated cancer comprising, as an active component, an anti-HER2 antibody-drug conjugate in which a drug-linker represented by the following formula (wherein A represents a connecting position to an anti-HER2 antibody) is conjugated to the antibody via a thioether bond and/or a method of treatment for cancer, comprising administering the anti-HER2 antibody-drug conjugate to a subject determined to have HER2-mutated cancer.
    Type: Application
    Filed: May 27, 2019
    Publication date: July 8, 2021
    Applicant: DAIICHI SANKYO COMPANY, LIMITED
    Inventors: Yoshihiko FUJISAKI, Yuta SATO, Yui SERIZAWA, Ryota SHIGA, Kaku SAITO, Takahiro JIKOH, Shinya TOKUHIRO
  • Check valve device and vapor fuel supply system
    Patent number: 10544757
    Abstract: A check valve device includes a valve portion elastically deformable to prevent or allow a flow of a vapor fuel through a fluid passage in one direction by contacting with or separating from a valve seat. An upstream passage forming member has the valve seat and the fluid passage located upstream of the valve portion. A downstream passage forming member includes a terminal portion housed in the upstream passage forming member and having a downstream passage. A narrowed passage provided inside the terminal portion or between the upstream passage forming member and the terminal portion. A cross-sectional area of the narrowed passage is set to be smaller than any of the fluid passage and the downstream passage.
    Type: Grant
    Filed: July 20, 2016
    Date of Patent: January 28, 2020
    Assignee: HAMANAKODENSO CO., LTD.
    Inventor: Yoshihiko Fujisaki
  • THERAPY FOR DRUG-RESISTANT CANCER BY ADMINISTRATION OF ANTI-HER2 ANTIBODY/DRUG CONJUGATE
    Publication number: 20190330368
    Abstract: As treatment effective for HER2-expressing cancer having resistance or refractoriness to an existing anti-HER2 drug, there are provided a therapeutic agent and a treatment method using an antibody-drug conjugate in which a linker and a drug represented by the formula: -(Succinimid-3-yl-N)—CH2CH2CH2CH2CH2—C(?O)-GGFG-NH—CH2—O—CH2—C(?O)—(NH-DX) are conjugated to an anti-HER2 antibody.
    Type: Application
    Filed: October 5, 2017
    Publication date: October 31, 2019
    Applicant: DAIICHI SANKYO COMPANY, LIMITED
    Inventors: Takahiro JIKOH, Yusuke OGITANI, Kazutaka YOSHIHARA, Seiko ENDO, Yoshihiko FUJISAKI
  • Check Valve Device And Vapor Fuel Supply System
    Publication number: 20170030301
    Abstract: A check valve device includes a valve portion elastically deformable to prevent or allow a flow of a vapor fuel through a fluid passage in one direction by contacting with or separating from a valve seat. An upstream passage forming member has the valve seat and the fluid passage located upstream of the valve portion. A downstream passage forming member includes a terminal portion housed in the upstream passage forming member and having a downstream passage. A narrowed passage provided inside the terminal portion or between the upstream passage forming member and the terminal portion. A cross-sectional area of the narrowed passage is set to be smaller than any of the fluid passage and the downstream passage.
    Type: Application
    Filed: July 20, 2016
    Publication date: February 2, 2017
    Inventor: Yoshihiko FUJISAKI