Abstract: Provided is a novel compound that has an excellent ?-lactamase inhibitory effect. More specifically, provided is a compound represented by formula (1a), (1b) or (11) having an excellent ?-lactamase inhibitory effect or a pharmaceutically acceptable salt thereof. By using this compound either in combination with a ?-lactam drug or alone, a useful preventive or therapeutic agent for bacterial infections is provided. Also provided are useful preventive or therapeutic agents for treating various diseases with the combined use of the aforesaid compound and ?-lactam drugs.

Abstract: Provided is a novel compound that has an excellent ?-lactamase inhibitory effect. More specifically, provided is a compound represented by formula (1a), (1b) or (11) having an excellent ?-lactamase inhibitory effect or a pharmaceutically acceptable salt thereof. By using this compound either in combination with a ?-lactam drug or alone, a useful preventive or therapeutic agent for bacterial infections is provided. Also provided are useful preventive or therapeutic agents for treating various diseases with the combined use of the aforesaid compound and ?-lactam drugs.

Abstract: Provided is a novel compound that has an excellent ?-lactamase inhibitory effect. More specifically, provided is a compound represented by formula (1a), (1b) or (11) having an excellent ?-lactamase inhibitory effect or a pharmaceutically acceptable salt thereof. By using this compound either in combination with a ?-lactam drug or alone, a useful preventive or therapeutic agent for bacterial infections is provided. Also provided are useful preventive or therapeutic agents for treating various diseases with the combined use of the aforesaid compound and ?-lactam drugs.

Abstract: Provided is a novel compound that has an excellent ?-lactamase inhibitory effect. More specifically, provided is a compound represented by formula (1a), (1b) or (11) having an excellent ?-lactamase inhibitory effect or a pharmaceutically acceptable salt thereof. By using this compound either in combination with a ?-lactam drug or alone, a useful preventive or therapeutic agent for bacterial infections is provided. Also provided are useful preventive or therapeutic agents for treating various diseases with the combined use of the aforesaid compound and ?-lactam drugs.

Abstract: The present invention relates to a method for the synthesis of cyclic depsipeptides, in particular emodepside, from the open form.

Abstract: A MODEM can shorten the processing time of an interface disposed between a data terminal equipment (DTE) and the MODEM. The MODEM stores an object program of a procedure in a memory and switches an operational mode of the MODEM automatically corresponding to the prescribed procedure thereby executing the procedure corresponding to the current operational mode. The MODEM further comprises a timer which monitors the transits time between a completed procedure and the next procedure, and the MODEM starts the process of a specified operational mode based on a mode-setting-instruction of the procedure as well as monitoring the transitions time by using the timer, and executing a next specified operational mode when the timer times out, thereby allowing the MODEM to perform the various operational mode switches.

Abstract: A MODEM can shorten the processing time of an interface disposed between a data terminal equipment (DTE) and the MODEM. The MODEM stores an object program of a procedure in a memory and switches an operational mode of the MODEM automatically corresponding to the prescribed procedure thereby executing the procedure corresponding to the current operational mode. The MODEM further comprises a timer which monitors the transits time between a completed procedure and the next procedure, and the MODEM starts the process of a specified operational mode based on a mode-setting-instruction of the procedure as well as monitoring the transitions time by using the timer, and executing a next specified operational mode when the timer times out, thereby allowing the MODEM to perform the various operational mode switches.

Abstract: A UV-sterilizer for a dental implement such as a reamer or drill permitting rapid and perfect irradiation and easy operation, comprising a sterilizer housing, a holder tube made of a transparent quartz glass tube and a plurality of UV-sterilizer lamps, both the holder tube and UV-sterilizer lamps being disposed within the sterilizer housing, wherein the sterilizer housing is provided with reflector plates and a gate mechanism substantially similar to a photographic diaphragm mechanism on an open end of the holder tube.