Abstract: A bispecific antibody including a first domain which specifically binds to a mutant calreticulin protein and a second domain which specifically binds to a CD3 antigen. A pharmaceutical composition including the bispecific antibody or a functional fragment thereof. A diagnostic method for a myeloproliferative neoplasm, including detecting a polypeptide in a biological sample with the bispecific antibody.

Abstract: A latch mechanism is configured to be shifted between a closed state in which a glove door is held on a compartment body at a closed position and an open state in which the glove door is not held on the compartment body. An operation lever is operated to shift the lock mechanism from the closed state to the open state. When the latch mechanism is shifted to the closed state, the first engaging member is engaged with the engagement hole. When the latch mechanism is shifted to the open state, the first engaging member is disengaged from the engagement hole. The compartment body includes an operation restriction wall that restricts operation of the first engaging member from the side surface of an instrument panel or the side surface of the compartment body so that the first engaging member is not disengaged from the engagement hole.

Abstract: A register faces a specific seat and feeds air to the specific seat. An hypothetical reference line is defined that extends in the front-back direction of the specific seat through the center in the width direction of the specific seat. In comparison between a first bezel side wall and a second bezel side wall, the second bezel side wall is positioned closer to the reference line than the first bezel side wall. A second duct side wall is bent such that a downstream side of the second duct side wall is positioned farther in the width direction from the reference line than an upstream side of the second duct side wall.

Abstract: A latch mechanism is configured to be shifted between a closed state in which a glove door is held on a compartment body at a closed position and an open state in which the glove door is not held on the compartment body. An operation lever is operated to shift the lock mechanism from the closed state to the open state. When the latch mechanism is shifted to the closed state, the first engaging member is engaged with the engagement hole. When the latch mechanism is shifted to the open state, the first engaging member is disengaged from the engagement hole. The compartment body includes an operation restriction wall that restricts operation of the first engaging member from the side surface of an instrument panel or the side surface of the compartment body so that the first engaging member is not disengaged from the engagement hole.

Abstract: To provide a vibration damping composition: excellent in vibration damping property and thermal drying property in a wide temperature range; and sufficiently suppressing sagging of a vibration damping coating film on the vertical surface; and therefore useful for vibration damping materials of various structures. A vibration damping composition comprising an emulsion for vibration damping materials, a foaming agent, and an inorganic pigment, wherein the emulsion for vibration damping materials comprises a particle having a core part formed from an acrylic copolymer (A) and a shell part formed from an acrylic copolymer (B), and at least one of the acrylic copolymers (A) and (B) is prepared by copolymerizing a monomer component comprising methacrylic acid.

Abstract: To provide a vibration damping composition: excellent in vibration damping property and thermal drying property in a wide temperature range; and sufficiently suppressing sagging of a vibration damping coating film on the vertical surface; and therefore useful for vibration damping materials of various structures. A vibration damping composition comprising an emulsion for vibration damping materials, a foaming agent, and an inorganic pigment, wherein the emulsion for vibration damping materials comprises a particle having a core part formed from an acrylic copolymer (A) and a shell part formed from an acrylic copolymer (B), and at least one of the acrylic copolymers (A) and (B) is prepared by copolymerizing a monomer component comprising methacrylic acid.