Patents by Inventor Yoshihiro DOI

Yoshihiro DOI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 2-[5-(imidazol-1-ylmethyl)pyridin-3-yl]benzimtdazole derivative compound, and medicament including same
    Patent number: 11266753
    Abstract: Provided are a compound represented by the following formula (1): wherein X1 represents a hydrogen atom or a halogen atom, X2 represents a fluorine atom or a nitrile group, and X3 represents a radioactive halogen atom, or a salt thereof, and a medicament including the same.
    Type: Grant
    Filed: December 20, 2018
    Date of Patent: March 8, 2022
    Assignees: NIHON MEDI-PHYSICS CO., LTD., NATIONAL HOSPITAL ORGANIZATION
    Inventors: Akihiro Izawa, Yuki Okumura, Yurie Fukui, Hiroaki Ichikawa, Yoshifumi Maya, Miho Ikenaga, Hiroyuki Okudaira, Yoshihiro Doi, Mitsuhide Naruse
  • 2-[5-(IMIDAZOL-1-YLMETHYL)PYRIDIN-3-YL]BENZIMIDAZOLE DERIVATIVE COMPOUND, AND MEDICAMENT INCLUDING SAME
    Publication number: 20210060186
    Abstract: Provided are a compound represented by the following formula (1): wherein X1 represents a hydrogen atom or a halogen atom, X2 represents a fluorine atom or a nitrile group, and X3 represents a radioactive halogen atom, or a salt thereof, and a medicament including the same.
    Type: Application
    Filed: December 20, 2018
    Publication date: March 4, 2021
    Applicants: Nihon Medi-Physics Co., Ltd., National Hospital Organization
    Inventors: Akihiro IZAWA, Yuki OKUMURA, Yurie FUKUI, Hiroaki ICHIKAWA, Yoshifumi MAYA, Miho IKENAGA, Hiroyuki OKUDAIRA, Yoshihiro DOI, Mitsuhide NARUSE
  • 2-(3-pyridinyl)-1H-benzimidazole derivative compound and medicament containing same
    Patent number: 10358434
    Abstract: Provided is a medicament comprising the compound represented by the following general formula (1) or a salt thereof: In the formula, R1, R2, R3, R4, R5, X1, X2, and X3 are defined. Methods for producing various radioactive compounds are also provided.
    Type: Grant
    Filed: December 6, 2018
    Date of Patent: July 23, 2019
    Assignees: NIHON MEDI-PHYSICS CO., LTD., KYOTO UNIVERSITY, NATIONAL HOSPITAL ORGANIZATION
    Inventors: Akihiro Izawa, Kei Akama, Yuki Okumura, Yurie Fukui, Nobuya Kobashi, Tsutomu Abe, Yoshihiro Doi, Miho Ikenaga, Hideo Saji, Hiroyuki Kimura, Mitsuhide Naruse
  • 2-(3-PYRIDINYL)-1H-BENZIMIDAZOLE DERIVATIVE COMPOUND AND MEDICAMENT CONTAINING SAME
    Publication number: 20190169169
    Abstract: Provided is a medicament comprising the compound represented by the following general formula (1) or a salt thereof: In the formula, R1, R2, R3, R4, R5, X1, X2, and X3 are defined. Methods for producing various radioactive compounds are also provided.
    Type: Application
    Filed: December 6, 2018
    Publication date: June 6, 2019
    Applicants: NIHON MEDI-PHYSICS CO., LTD., Kyoto University, National Hospital Organization
    Inventors: Akihiro IZAWA, Kei AKAMA, Yuki OKUMURA, Yurie FUKUI, Nobuya KOBASHI, Tsutomu ABE, Yoshihiro DOI, Miho IKENAGA, Hideo SAJI, Hiroyuki KIMURA, Mitsuhide NARUSE
  • 2-(3-pyridinyl)-1H-benzimidazole derivative compound and medicine containing same
    Patent number: 10189815
    Abstract: Provided is a compound represented by general formula (1) or a salt thereof as well as a medicine containing the compound or the salt. In the formula, R1, R2, R3, R4, R5, X1, X2, and X3 are defined.
    Type: Grant
    Filed: June 25, 2015
    Date of Patent: January 29, 2019
    Assignees: NIHON MEDI-PHYSICS CO., LTD., KYOTO UNIVERSITY, NATIONAL HOSPITAL ORGANIZATION
    Inventors: Akihiro Izawa, Kei Akama, Yuki Okumura, Yurie Fukui, Nobuya Kobashi, Tsutomu Abe, Yoshihiro Doi, Miho Ikenaga, Hideo Saji, Hiroyuki Kimura, Mitsuhide Naruse
  • METHOD FOR PRODUCING ANIMAL MODEL OF OSTEOBLASTIC BONE METASTASIS
    Publication number: 20170265441
    Abstract: Provided is a method for producing an animal model of osteoblastic bone metastasis. A non-human animal in which an osteoblastic lesion is formed in a wide range has been successfully produced with a probability of 100% by: administering a calcineurin inhibitor to a non-human animal; and injecting a tumor cell into an artery or a vein of the non-human animal, wherein the non-human animal and the tumor cell are in an allogeneic or xenogeneic relation.
    Type: Application
    Filed: February 28, 2017
    Publication date: September 21, 2017
    Applicant: NIHON MEDI-PHYSICS CO., LTD.
    Inventors: Shuntaro OKA, Masaru KANAGAWA, Masahiro ONO, Yoshihiro DOI
  • Method for Evaluating Nuclear Medicine Image of Head
    Publication number: 20170231591
    Abstract: To provide a technique for evaluating a nuclear medicine brain image, the technique being hardly affected by the difference in the setting of reference regions. An embodiment of the present invention generally includes: setting a reference region on a region corresponding to the scalp in the nuclear medicine brain image; calculating information on a pixel value in the set reference region; and normalizing, using the information, a pixel value of each pixel included in the nuclear medicine brain image or a value obtained from the pixel value, and outputting the normalized value.
    Type: Application
    Filed: October 29, 2015
    Publication date: August 17, 2017
    Applicant: Nihon Medi-Physics Co., Ltd.
    Inventors: Akihiro MURATA, Shigenori MORISHITA, Yoshihiro DOI, Ryohei KOBAYASHI
  • 2-(3-PYRIDINYL)-1H-BENZIMIDAZOLE DERIVATIVE COMPOUND AND MEDICINE CONTAINING SAME
    Publication number: 20170158668
    Abstract: Provided is a compound represented by general formula (1) or a salt thereof as well as a medicine containing the compound or the salt. In the formula, R1, R2, R3, R4, R5, X1, X2, and X3 are defined.
    Type: Application
    Filed: June 25, 2015
    Publication date: June 8, 2017
    Applicants: Nihon Medi-Physics Co., Ltd., Kyoto University, National Hospital Organization
    Inventors: Akihiro IZAWA, Kei AKAMA, Yuki OKUMURA, Yurie FUKUI, Nobuya KOBASHI, Tsutomu ABE, Yoshihiro DOI, Miho IKENAGA, Hideo SAJI, Hiroyuki KIMURA, Mitsuhide NARUSE