Patents by Inventor Yoshihiro Horiuchi
Yoshihiro Horiuchi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8933229Abstract: Disclosed is a compound represented by formula (1) or a pharmacologically acceptable salt thereof (In the formula, A represents a group that is represented by formula (A-1); R1a and R1b may be the same or different and each independently represents a C1-6 alkyl group which may be substituted by one to three halogen atoms; m and n each independently represents an integer of 0-5; X1 represents a hydroxyl group or an aminocarbonyl group; Z1 represents a single bond or the like; and R2 represents an optionally substituted C1-6 alkyl group, an optionally substituted C6-10 aryl group or the like).Type: GrantFiled: November 11, 2010Date of Patent: January 13, 2015Assignee: Sumitomo Dainippon Pharma Co., Ltd.Inventors: Yoshihiro Horiuchi, Kiyoto Sawamura, Hiroaki Fujiwara
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Patent number: 8895552Abstract: Provided is a compound represented by formula (1) or a pharmacologically acceptable salt thereof. (In the formula, A is C6-10 arylene, etc.; R1a, R1b and R1c each independently is a hydrogen atom, a halogen atom, a C1-4 alkyl group, a C1-4 alkoxy group, etc.; R2 is an optionally substituted C6-10 aryl group, an optionally substituted 5- to 12-membered monocyclic or polycyclic heteroaryl group, an optionally substituted C7-16 aralkyl group, etc.; m is 0, etc.; n is an integer of 0 to 2.Type: GrantFiled: September 2, 2011Date of Patent: November 25, 2014Assignee: Sumitomo Dainippon Pharma Co., Ltd.Inventors: Yoshihiro Horiuchi, Hiroaki Fujiwara, Hitoshi Suda, Izumi Sasaki, Mitsutaka Iwata, Kiyoto Sawamura
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Publication number: 20130217692Abstract: Provided is a compound represented by formula (1) or a pharmacologically acceptable salt thereof. (In the formula, A is C6-10 arylene, etc.; R1a, R1b and R1c each independently is a hydrogen atom, a halogen atom, a C1-4 alkyl group, a C1-4 alkoxy group, etc.; R2 is an optionally substituted C6-10 aryl group, an optionally substituted 5- to 12-membered monocyclic or polycyclic heteroaryl group, an optionally substituted C7-16 aralkyl group, etc.; m is 0, etc.; n is an integer of 0 to 2.Type: ApplicationFiled: September 2, 2011Publication date: August 22, 2013Applicant: DAINIPPON SUMITOMO PHARMA CO., LTD.Inventors: Yoshihiro Horiuchi, Hiroaki Fujiwara, Hitoshi Suda, Izumi Sasaki, Mitsutaka Iwata, Kiyoto Sawamura
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Publication number: 20120225876Abstract: Disclosed is a compound represented by formula (1) or a pharmacologically acceptable salt thereof (In the formula, A represents a group that is represented by formula (A-1); R1a and R1b may be the same or different and each independently represents a C1-6 alkyl group which may be substituted by one to three halogen atoms; m and n each independently represents an integer of 0-5; X1 represents a hydroxyl group or an aminocarbonyl group; Z1 represents a single bond or the like; and R2 represents an optionally substituted C1-6 alkyl group, an optionally substituted C6-10 aryl group or the like.Type: ApplicationFiled: November 11, 2010Publication date: September 6, 2012Applicant: DAINIPPON SUMITOMO PHARMA CO., LTD.Inventors: Yoshihiro Horiuchi, Kiyoto Sawamura, Hiroaki Fujiwara
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Publication number: 20110071289Abstract: Disclosed is a compound represented by the formula (1) below or a pharmaceutically acceptable salt thereof, which is useful as an agent for prevention and/or treatment of diabetes and the like. (In the formula, RA and RB independently represent an optionally substituted alkyl group or the like; RC represents an optionally substituted alkyl group or the like; RD represents a hydrogen atom or the like; RE represents a hydrogen atom or the like; and RF represents a group selected from those represented by the formulae (G1) below: wherein one hydrogen atom serves as a bonding hand, or the like.Type: ApplicationFiled: August 6, 2008Publication date: March 24, 2011Applicant: DAINIPPON SUMITOMO PHARMA CO., LTD.Inventors: Yoshihiro Horiuchi, Noriko Nunami, Hiroto Tatamidani, Eiko Ohata
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Patent number: 7879843Abstract: A medicine which contains as an active ingredient a benzothiazin-3-one-compound represented by the formula (1): (wherein n is 3 or 4; R represents ethyl or hydrogen; and R1 represents hologeno, alkoxy, haloalkyl, or haloalkoxy) or a pharmaceutically acceptable salt thereof. It is useful as a therapeutic or preventive agent for arthrosis deformans, chondrodegenerative discases such as chronic articular rheumatism, cancers, gingivitis, etc. Also provided are an intermediate for the compound and a process for producing the compound.Type: GrantFiled: August 26, 2009Date of Patent: February 1, 2011Assignee: Dainippon Sumitomo Pharma Co., Ltd.Inventors: Fumio Samizo, Yoshihiro Horiuchi, Nobuhisa Fukuda, Katsunori Tsuboi, Atsushi Makita
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Publication number: 20100009976Abstract: A medicine which contains as an active ingredient a benzothiazin-3-one-compound represented by the formula (1): (wherein n is 3 or 4; R represents ethyl or hydrogen; and R1 represents hologeno, alkoxy, haloalkyl, or haloalkoxy) or a pharmaceutically acceptable salt thereof. It is useful as a therapeutic or preventive agent for arthrosis deformans, chondrodegenerative discases such as chronic articular rheumatism, cancers, gingivitis, etc. Also provided are an intermediate for the compound and a process for producing the compound.Type: ApplicationFiled: August 26, 2009Publication date: January 14, 2010Applicant: DAINIPPON SUMITOMO PHARMA CO., LTD.Inventors: Fumio Samizo, Yoshihiro HORIUCHI, Nobuhisa Fukuda, Katsunori Tsuboi, Atsushi Makita
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Patent number: 7598240Abstract: A medicine which contains as an active ingredient a benzothiazin-3-one-compound represented by the formula (1): (wherein n is 3 or 4; R represents ethyl or hydrogen; and R1 represents hologeno, alkoxy, haloalkyl, or haloalkoxy) or a pharmaceutically acceptable salt thereof. It is useful as a therapeutic or preventive agent for arthrosis deformans, chondrodegenerative discases such as chronic articular rheumatism, cancers, gingivitis, etc. Also provided are an intermediate for the compound and a process for producing the compound.Type: GrantFiled: February 28, 2005Date of Patent: October 6, 2009Assignee: Dainippon Sumitomo Pharma Co., Ltd.Inventors: Fumio Samizo, Yoshihiro Horiuchi, Nobuhisa Fukuda, Katsunori Tsuboi, Atsushi Makita
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Patent number: 7504537Abstract: A hydroxamic acid derivative represented by the following general formula (1) having selective MMP inhibitory activity, wherein R1 and R2 each represents hydrogen atom, lower alkyl group, lower haloalkyl etc., X represents methylene group or NR3 (R3 represents hydrogen atom, lower alkyl group, etc.), and R4 represents C1˜4 lower alkyl group.Type: GrantFiled: December 26, 2002Date of Patent: March 17, 2009Assignee: Dainippon Sumitomo Pharma Co., Ltd.Inventor: Yoshihiro Horiuchi
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Publication number: 20080058321Abstract: A medicine which contains as an active ingredient a benzothiazin-3-one-compound represented by the formula (1): (wherein n is 3 or 4; R represents ethyl or hydrogen; and R1 represents hologeno, alkoxy, haloalkyl, or haloalkoxy) or a pharmaceutically acceptable salt thereof. It is useful as a therapeutic or preventive agent for arthrosis deformans, chondrodegenerative discases such as chronic articular rheumatism, cancers, gingivitis, etc. Also provided are an intermediate for the compound and a process for producing the compound.Type: ApplicationFiled: February 28, 2005Publication date: March 6, 2008Applicant: DAINIPPON SUMITOMO PHARMA CO., LTD.Inventors: Fumio Samizo, Yoshihiro Horiuchi, Nobuhisa Fukuda, Katsunori Tsuboi, Atsushi Makita
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Publication number: 20050282905Abstract: A hydroxamic acid derivative represented by the following general formula (1) having selective MMP inhibitory activity, ,wherein R1 and R2 each represents hydrogen atom, lower alkyl group, lower haloalkyl etc., X represents methylene group or NR3 (R3 represents hydrogen atom, lower alkyl group, etc.), and R4 represents C1˜4 lower alkyl group.Type: ApplicationFiled: December 26, 2002Publication date: December 22, 2005Inventor: Yoshihiro Horiuchi