Patents by Inventor Yoshihiro Ichihara

Yoshihiro Ichihara has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Intermediates for synthesis of vitamin D derivatives
    Patent number: 7598408
    Abstract: The present invention provides a novel intermediate for synthesizing vitamin D derivatives by using a less expensive material. That is, the present invention provides a compound which is synthesized by using carvone as a starting material and which is represented by the following formulae.
    Type: Grant
    Filed: February 18, 2004
    Date of Patent: October 6, 2009
    Assignee: KNC Laboratories Co., Ltd.
    Inventors: Hidekazu Imahori, Hiroya Koyama, Daisuke Yoshihara, Yoshinori Sawashita, Sota Kurita, Yoshihiro Ichihara, Yoshihiro Takagi, Katsutoshi Hirose
  • Novel intermediates for synthesis of vitamin d derivatives
    Publication number: 20060106242
    Abstract: The present invention provides a novel intermediate for synthesizing vitamin D derivatives by using a less expensive material. That is, the present invention provides a compound which is synthesized by using carvone as a starting material and which is represented by the following formulae.
    Type: Application
    Filed: February 18, 2004
    Publication date: May 18, 2006
    Inventors: Hidekazu Imahori, Hiroya Koyama, Daisuke Yoshihara, Yoshinori Sawashita, Sota Kurita, Yoshihiro Ichihara, Yoshihiro Takagi, Katsutoshi Hirose
  • Pregnane derivatives and method of producing the same
    Patent number: 4867914
    Abstract: There are provided 12-hydroxy-.DELTA..sup.4 or .DELTA..sup.1,4 -pregnan-3-one-20-carbaldehyde and microbial method of producing the same. The compounds are novel and useful as starting materials for the synthesis of corticoids, typically prednisone, prednisolone and hydrocortisone, which have antiinflammatory activity.
    Type: Grant
    Filed: September 26, 1986
    Date of Patent: September 19, 1989
    Assignee: Kuraray Co., Ltd.
    Inventors: Masayasu Bunno, Hidemi Harada, Masao Tsuji, Yoshihiro Ichihara
  • 12.alpha.-substituted pregna-1,4-diene-3,20-diones
    Patent number: 4867913
    Abstract: 12.alpha.-Substituted pregna-1,4-diene-3,20-diones, which are novel compounds, are provided. These compounds are useful as intermediates for the synthesis of antiinflammatory corticoids represented by prednisone, prednisolone, etc.
    Type: Grant
    Filed: August 20, 1986
    Date of Patent: September 19, 1989
    Assignee: Kuraray Co., Ltd.
    Inventors: Masayasu Bunno, Hidemi Harada, Masao Tsuji, Tsutomu Sugiura, Yoshihiro Ichihara
  • 11-hydroxypregn-4-en-3-one-20-carbaldehyde and a method for its production
    Patent number: 4592868
    Abstract: There is provided the novel compound 11-hydroxypregn-4-en-3-one-20-carbaldehyde, as well as a microbial method for production of the same. This novel compound is of value as a starting material for antiinflammatory corticoids such as hydrocortisone, cortisone, prednisolone and prednisone.
    Type: Grant
    Filed: May 7, 1984
    Date of Patent: June 3, 1986
    Assignee: Kuraray Co., Ltd.
    Inventors: Masao Tsuji, Fumio Mori, Yoshihiro Ichihara
  • Microbial process for producing 12.alpha.-hydroxypregna-1,4-dien-3-one-20.alpha.-carboxylic acid
    Patent number: 4520102
    Abstract: A microbial process for producing 12.alpha.-hydroxypregna-1,4-dien-3-one-20.alpha.-carboxylic acid or a salt thereof which comprises cultivating a microbe of the species Pseudomonas arvilla or the genus Alcaligenes, e.g. Alcaligenes faecalis, which is capable of producing 12.alpha.-hydroxypregna-1,4-dien-3-one-20.alpha.-carboxylic acid or a salt thereof by utilizing deoxycholic acid or a salt thereof as a substrate, in a culture medium containing the substrate and collecting the resulting compound.
    Type: Grant
    Filed: October 15, 1982
    Date of Patent: May 28, 1985
    Assignee: Kuraray Co., Ltd.
    Inventors: Masayasu Bunno, Tsutomu Sugiura, Masao Tsuji, Hidemi Harada, Yoshihiro Ichihara
  • Microbial process for producing cholanic acid derivatives
    Patent number: 4359529
    Abstract: A microbial process for producing a cholanic acid derivative of the formula: ##STR1## wherein X is ##STR2## or .dbd.O; and R is hydrogen, an alkali metal or an alkaline earth metal, which comprises cultivating a microbe which is capable of growing in a medium containing cholic acid or a salt thereof as a substrate to produce the cholanic acid derivative, selected from the genera Arthrobacter, Brevibacterium and Corynebacterium, in a culture medium containing the substrate and collecting the resulting derivative.
    Type: Grant
    Filed: July 30, 1980
    Date of Patent: November 16, 1982
    Assignee: Kuraray Co., Ltd.
    Inventors: Masao Tsuji, Yoshihiro Ichihara