Patents by Inventor Yoshihiro Ishizue

Yoshihiro Ishizue has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Highly absorbable pharmaceutical composition
    Patent number: 5445830
    Abstract: A highly absorbable pharmaceutical composition containing, as the active ingredient, methyl 3-phenyl-2(E)-propenyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate in an amorphous state and a pH-dependent type copolymer of methacrylic acid or its derivatives which composition has been prepared by dissolving the two components together in an organic solvent and thereafter removing the solvent.
    Type: Grant
    Filed: February 12, 1993
    Date of Patent: August 29, 1995
    Assignee: Otsuka Pharmaceutical Co., Ltd.
    Inventors: Yoshihiro Ishizue, Kozo Ishida, Masaaki Odomi, Toru Nishibayashi, Kaszuyo Koshino
  • Particulate preparation containing a flourracil derivative and hydroxypropylmethyl-cellulose
    Patent number: 5316773
    Abstract: The solid preparation of the invention is prepared by dissolving 3-[3-(6-Benzoyloxy-3-cyano-2-pyridyloxycarbonyl)benzoyl]-1-ethoxymethyl-5- fluorouracil (hereinafter referred to as "BOF-A2") and a water-soluble polymer in a organic solvent completely, followed by forming preparation of amorphous powder prepared by removing the organic solvent.The solid preparation is useful to enhance solubility of BOF-A2 and to accomplish rapid absorption of BOF-A2 through the alimentary canal.
    Type: Grant
    Filed: March 16, 1992
    Date of Patent: May 31, 1994
    Assignee: Otsuka Pharmaceutical Co., Ltd.
    Inventors: Toru Nishibayashi, Yoshihiro Ishizue, Kozo Ishida, Masanori Kubo