Abstract: A handpiece-type high-frequency vibration cutting device includes a housing (10); a vibration device (21); a holding member (11); a tool (12); and a controller (20) to control the operations of the vibration device (21). The controller (20) controls the vibration of the tool (12) due to the vibration device (21) such that the vibration is burst oscillation in which vibration and stop of vibration are repeated. The controller (20) also controls the entire burst frequency f1 of the tool (12) to be included in the range of 1 to 8 [Hz], one cycle of the burst frequency f1 including a burst period with the holding member (11) vibrating and a stop period with the tool (12) not vibrating. The controller (20) also controls the vibration frequency f2 of the tool (12) during the burst period such that the vibration frequency f2 is in the range of 20 to 60 [kHz].

Abstract: The handpiece-type high-frequency vibration apparatus includes a roughly cylindrical housing 10 configuring a handpiece, a holding member 11, a tool 12, a controller 20 and an excitation device 21. In a non-contact state before the tool 12 is brought into contact with an object, the controller 20 drives the excitation device 21 so as to vibrate the tool 12 at an added frequency fp for which a predetermined frequency fs is added to a first resonance frequency fr1 of the tool 12. In a cutting state where the tool 12 is in contact with the object by a load that enables cutting of the object by the tool 12, the controller 20 controls drive of the excitation device 21 such that a third resonance frequency fr3 of the tool 12 increases and coincides with the added frequency fp, and increases a vibration frequency of the tool 12.

Abstract: A vibration type removal apparatus 2 includes a housing 10, a holding member 11, a tool 12, a control device 20, a vibration device 21, and a cooling pump 22. The control device 20 drives the cooling pump 22, and cooling water supplied from the cooling pump 22 passes through a flow path 25 in the housing 10, and is sprayed toward the tool 12 from a distal end of the flow path 25. In this state, the tool 12 is inserted between a hard tissue HT and a soft tissue ST, the vibration device 21 is operated, and the tool 12 is vibrated. Due to the vibration of the tool 12, a surface of the hard tissue HT which adheres to the soft tissue ST is cut, and the hard tissue HT is peeled and removed from the soft tissue ST.

Abstract: There is provided a method of detecting a microscopic body stored in a plurality of receptacles formed separately from each other. The method, which is provided as a technique for enclosing a to-be-detected substance such as nucleic acid, protein, virus, and cell by means of a simple operation in droplets of an extremely small volume and enabling highly sensitive detection, includes the steps of (1) introducing a solvent into a space between a lower layer part in which the receptacles are formed and an upper layer part facing a surface of the lower layer part in which surface the receptacles are formed, wherein the solvent contains the microscopic body; (2) introducing gas into the space to form a droplet of the solvent in the receptacles, wherein the droplet contains the microscopic body; and (3) detecting the microscopic body present in the droplet optically, electrically, and/or magnetically.

Abstract: Provided is a technique that can be used to detect a pathogenic microorganism such as influenza virus with high sensitivity, and specifically, a method for detecting a reaction product, including reacting an enzyme with a substance serving as a substrate for a reaction involving the enzyme in a hydrophilic solvent that is in interfacial contact with a hydrophobic solvent, wherein the reaction product is produced directly and released from the substrate, and wherein the hydrophilic solvent contains at least one of a buffering substance or trimethylamine oxide (TMAO).

Abstract: A handpiece-type high-frequency vibration cutting device includes a housing (10); a vibration device (21); a holding member (11); a tool (12); and a controller (20) to control the operations of the vibration device (21). The controller (20) controls the vibration of the tool (12) due to the vibration device (21) such that the vibration is burst oscillation in which vibration and stop of vibration are repeated. The controller (20) also controls the entire burst frequency f1 of the tool (12) to be included in the range of 1 to 8 [Hz], one cycle of the burst frequency f1 including a burst period with the holding member (11) vibrating and a stop period with the tool (12) not vibrating. The controller (20) also controls the vibration frequency f2 of the tool (12) during the burst period such that the vibration frequency f2 is in the range of 20 to 60 [kHz].