Patents by Inventor Yoshihiro Shigemasa

Yoshihiro Shigemasa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Phenol derivatives and antitrypanosoma preventive/therapeutic agent comprising the same as active ingredient
    Patent number: 7622598
    Abstract: A compound represented by formula (I): [wherein, for example, X is a hydrogen atom or a halogen atom; R1 is a hydrogen atom; R2 is a hydrogen atom or a C1-4 alkyl group; R3 is —CHO or —COOH; and R4 is —CH?CH—(CH2)p—CH3 (wherein p is an integer of 1 to 12), —CH(OH)—(CH2)q—CH3 (wherein q is an integer of 1 to 13), —CH(OH)—CH2—CH(CH3)—(CH2)2—CH?C(CH3)2, —CH?CH—CH(CH3)—(CH2)3—CH(CH3)2, —(CH2)2—CH(CH3)—(CH2)3—CH(CH3)2 or —(CH2)8—CH3], an optical isomer thereof and a pharmaceutically acceptable salt thereof. These compounds have antitrypanosoma activity, and accordingly are useful as drugs for preventing or treating the diseases caused by trypanosoma.
    Type: Grant
    Filed: October 18, 2004
    Date of Patent: November 24, 2009
    Assignee: aRigen Pharmaceuticals, Inc.
    Inventors: Hiroyuki Saimoto, Yoshihiro Shigemasa, Kiyoshi Kita, Yoshisada Yabu, Tomoyoshi Hosokawa, Masaichi Yamamoto
  • NOVEL PHENOL DERIVATIVES AND ANTITRYPANOSOMA PREVENTIVE/THERAPEUTIC AGENT COMPRISING THE SAME AS ACTIVE INGREDIENT
    Publication number: 20070208078
    Abstract: A compound represented by formula (I): [wherein, for example, X is a hydrogen atom or a halogen atom; R1 is a hydrogen atom; R2 is a hydrogen atom or a C1-4 alkyl group; R3 is —CHO or —COOH; and R4 is —CH?CH—(CH2)p—CH3 (wherein p is an integer of 1 to 12), —CH(OH)—(CH2)q—CH3 (wherein q is an integer of 1 to 13), —CH(OH)—CH2—CH(CH3)—(CH2)2—CH?C(CH3)2, —CH?CH—CH(CH3)—(CH2)3—CH(CH3)2, —(CH2)2—CH(CH3)—(CH2)3—CH(CH3)2 or —(CH2)8—CH3], an optical isomer thereof and a pharmaceutically acceptable salt thereof. These compounds have antitrypanosoma activity, and accordingly are useful as drugs for preventing or treating the diseases caused by trypanosoma.
    Type: Application
    Filed: October 18, 2004
    Publication date: September 6, 2007
    Applicant: aRigen, Inc.
    Inventors: Hiroyuki Saimoto, Yoshihiro Shigemasa, Kiyoshi Kita, Yoshisada Yabu, Tomoyoshi Hosokawa, Masaichi Yamamoto