Patents by Inventor Yoshihiro Sowa

Yoshihiro Sowa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CELL PREPARATION METHOD
    Publication number: 20240124842
    Abstract: Provided is a method of preparing a somatic cell including converting a differentiated somatic cell of a mammal to other somatic cell by culturing the differentiated somatic cell in a medium for inducing differentiation of the somatic cell other than the differentiated somatic cell in the presence of a TGF-? pathway inhibitor.
    Type: Application
    Filed: December 22, 2023
    Publication date: April 18, 2024
    Applicant: KYOTO PREFECTURAL PUBLIC UNIVERSITY CORPORATION
    Inventors: Kenta YAMAMOTO, Tsunao KISHIDA, Yoshihiro SOWA, Toshiro YAMAMOTO, Osam MAZDA
  • METHOD FOR PRODUCING THREE-DIMENSIONAL TISSUE BODY AND METHOD FOR PROMOTING DIFFERENTIATION OF ADIPOSE-DERIVED STEM CELLS
    Publication number: 20240117313
    Abstract: A method for producing a three-dimensional tissue construct comprising mature adipocytes, comprising incubating cells comprising at least fat-derived stein cells in the presence of one or more fatty acids selected from the group consisting of erucic acid, elaidic acid, oleic acid, palmitoleic acid, myristoleic acid, phytanic acid, and pristanic acid.
    Type: Application
    Filed: February 15, 2022
    Publication date: April 11, 2024
    Applicants: TOPPAN INC., OSAKA UNIVERSITY, Kyoto Prefectural Public University Corporation
    Inventors: Shiro KITANO, Michiya MATSUSAKI, Fiona LOUIS, Yoshihiro SOWA
  • Cell preparation method
    Patent number: 11851681
    Abstract: Provided is a method of preparing a somatic cell including converting a differentiated somatic cell of a mammal to other somatic cell by culturing the differentiated somatic cell in a medium for inducing differentiation of the somatic cell other than the differentiated somatic cell in the presence of a TGF-? pathway inhibitor.
    Type: Grant
    Filed: October 20, 2016
    Date of Patent: December 26, 2023
    Assignee: KYOTO PREFECTURAL PUBLIC UNIVERSITY CORPORATION
    Inventors: Kenta Yamamoto, Tsunao Kishida, Yoshihiro Sowa, Toshiro Yamamoto, Osam Mazda
  • METHOD FOR FREEZING CELL STRUCTURE
    Publication number: 20230389540
    Abstract: The present invention relates to a method for freezing a cell structure including freezing a cell structure including fragmented extracellular matrix components, cells and fibrin and having a three-dimensional tissue structure.
    Type: Application
    Filed: October 15, 2021
    Publication date: December 7, 2023
    Applicants: OSAKA UNIVERSITY, TOPPAN INC., Kyoto Prefectural Public University Corporation
    Inventors: Michiya MATSUSAKI, Fiona LOUIS, Shiro KITANO, Yoshihiro SOWA
  • CELL CONSTRUCT AND CELL CONSTRUCT PRODUCTION METHOD
    Publication number: 20220170911
    Abstract: Disclosed is a cell structure comprising: a fragmented extracellular matrix component; and cells, wherein the cell structure comprises an intercellular vascular network, and the cells comprise at least adipocytes and vascular endothelial cells.
    Type: Application
    Filed: March 19, 2020
    Publication date: June 2, 2022
    Applicants: TOPPAN INC., OSAKA UNIVERSITY, Kyoto Prefectural Public University Corporation
    Inventors: Shiro KITANO, Shinji IRIE, Michiya MATSUSAKI, Fiona LOUIS, Yoshihiro SOWA
  • Schwann cells and method for preparing same
    Patent number: 10675382
    Abstract: The present invention addresses the problem of providing a method for obtaining Schwann cells directly (by direct reprogramming) without passing through pluripotent stem cells, such as ES cells or iPS cells. As a means for solving this problem, the present invention provides a method for preparing Schwann cells that includes a step of introducing into somatic cells of a mammal at least one gene selected from the group consisting of SOX10 genes and KROX20 genes, or an expression product thereof.
    Type: Grant
    Filed: September 11, 2015
    Date of Patent: June 9, 2020
    Assignee: KYOTO PREFECTURAL PUBLIC UNIVERSITY CORPORATION
    Inventors: Yoshihiro Sowa, Tsunao Kishida, Osam Mazda
  • CELL PREPARATION METHOD
    Publication number: 20190024054
    Abstract: Provided is a method of preparing a somatic cell including converting a differentiated somatic cell of a mammal to other somatic cell by culturing the differentiated somatic cell in a medium for inducing differentiation of the somatic cell other than the differentiated somatic cell in the presence of a TGF-? pathway inhibitor.
    Type: Application
    Filed: October 20, 2016
    Publication date: January 24, 2019
    Applicant: KYOTO PREFECTURAL PUBLIC UNIVERSITY CORPORATION
    Inventors: Kenta YAMAMOTO, Tsunao KISHIDA, Yoshihiro SOWA, Toshiro YAMAMOTO, Osam MAZDA
  • SCHWANN CELLS AND METHOD FOR PREPARING SAME
    Publication number: 20170252484
    Abstract: The present invention addresses the problem of providing a method for obtaining Schwann cells directly (by direct reprogramming) without passing through pluripotent stem cells, such as ES cells or iPS cells. As a means for solving this problem, the present invention provides a method for preparing Schwann cells that includes a step of introducing into somatic cells of a mammal at least one gene selected from the group consisting of SOX10 genes and KROX20 genes, or an expression product thereof.
    Type: Application
    Filed: September 11, 2015
    Publication date: September 7, 2017
    Applicant: KYOTO PREFECTURAL PUBLIC UNIVERSITY CORPORATION
    Inventors: Yoshihiro SOWA, Tsunao KISHIDA, Osam MAZDA
  • Method for screening anticancer agent
    Patent number: 7407745
    Abstract: By analyzing the mechanism for inducing a histone deacetylase inhibitor (Trichostatin A)-mediated expression of cyclin-CDK inhibitory factor having a proliferation suppressing effect (tumor-suppressing effect), it was revealed that the binding of Sp3 to the Sp1 binding sequence within a promoter is important in the expression of the above factor. Thus, a novel antitumor agent can be developed by screening a pharmaceutical agent capable of elevating Sp3 activity.
    Type: Grant
    Filed: March 23, 2000
    Date of Patent: August 5, 2008
    Assignee: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Yoshihiro Sowa, Tetsuro Orita