Patents by Inventor Yoshihisa Koyama
Yoshihisa Koyama has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240269165Abstract: An object is to provide a pharmaceutical or the like that can prevent or treat non-alcoholic fatty liver disease, pain associated with inactivity, or acute pancreatitis. [Solving Means] When silicon small particles are orally administered or placed on a skin or a mucous membrane, non-alcoholic fatty liver disease, pain associated with inactivity, and acute pancreatitis can be prevented or treated. The silicon small particles are particles each of which generates hydrogen when brought into contact with an aqueous solution having a pH of 7 or more. Provided is a preventive or therapeutic agent, pharmaceutical composition, medical device, food, or beverage comprising the silicon small particles for non-alcoholic fatty liver disease, pain associated with inactivity, or acute pancreatitis. The silicon small particles are suitably silicon fine particles and/or aggregates of the silicon fine particles.Type: ApplicationFiled: May 31, 2022Publication date: August 15, 2024Applicant: Osaka UniversityInventors: Shoichi Shimada, Yoshihisa Koyama, Makoto Kondo, Noriyoshi Usui, Hikaru Kobayashi, Yuki Kobayashi
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Publication number: 20210145865Abstract: An object is to provide a pharmaceutical or the like that can prevent or treat an oxidative stress-induced disease. Provided is a preventive or therapeutic agent for an oxidative stress-induced disease, pharmaceutical composition, medical device, hygienic product, food, or beverage containing silicon small particles. When the silicon small particles are orally administered or placed on a skin or a mucous membrane, the oxidative stress-induced disease can be prevented or treated. The oxidative stress-induced disease is an inflammatory disease, depression, or the like, and an excellent preventive and therapeutic effect thereon is obtained.Type: ApplicationFiled: December 7, 2020Publication date: May 20, 2021Inventors: Shoichi SHIMADA, Yoshihisa KOYAMA, Makoto KONDO, Noriyoshi USUI, Kazuya OHATA, Hidenori INOHARA, Hikaru KOBAYASHI, Yuki KOBAYASHI
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Patent number: 7229971Abstract: This invention relates to a method for regulating the biodegradability of composite biomaterials comprising calcium salt (particularly hydroxyapatite) and collagen, improved composite biomaterials obtained via such method, and a method for increasing bone mass with the use of such composite biomaterials.Type: GrantFiled: September 10, 2004Date of Patent: June 12, 2007Assignees: Japan Science and Technology Agency, National Institute for Materials Science, Nitta Gelatin Inc.Inventors: Junzo Tanaka, Masanori Kikuchi, Noriichi Ito, Yoshinobu Mandai, Hiroko Matsumoto, Yoshihisa Koyama, Kazuo Takakuda
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Publication number: 20050042252Abstract: This invention relates to a method for regulating the biodegradability of composite biomaterials comprising calcium salt (particularly hydroxyapatite) and collagen, improved composite biomaterials obtained via such method, and a method for increasing bone mass with the use of such composite biomaterials.Type: ApplicationFiled: September 10, 2004Publication date: February 24, 2005Applicants: JAPAN SCIENCE AND TECHNOLOGY AGENCY, NATIONAL INSTITUTE FOR MATERIALS SCIENCE, NITTA GELATIN INC.Inventors: Junzo Tanaka, Masanori Kikuchi, Noriichi Ito, Yoshinobu Mandai, Hiroko Matsumoto, Yoshihisa Koyama, Kazuo Takakuda
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Patent number: 6441073Abstract: The followings are disclosed herein: a biomaterial comprising calcium phosphate and a copolymer of lactic acid, glycolic acid and &egr;-caprolactone; a biomaterial for the induction of osteoanagenesis, characterized in that a periosteum is attached to the biomaterial comprising calcium phosphate and a copolymer of lactic acid, glycolic acid and &egr;-caprolactone; and a biomaterial for the prevention of adhesion comprising calcium phosphate and a copolymer of lactic acid, glycolic acid and &egr;-caprolactone where the molar ratio of lactic acid, glycolic acid and &egr;-caprolactone is within a range of 5-90:3-75:5-40.Type: GrantFiled: April 17, 2001Date of Patent: August 27, 2002Assignees: Taki Chemical Co., Ltd., National Institute for Material Science PresidentInventors: Junzo Tanaka, Masanori Kikuchi, Kimihiro Miyamoto, Shuji Suwa, Shunji Ichikawa, Etsuro Yokoyama, Soichi Shono, Takao Okada, Yukari Imamura, Kazuo Takakuda, Yoshihisa Koyama, Shigeo Tanaka, Noriaki Shirahama, Takatoshi Itoh
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Patent number: 6169046Abstract: The present invention provides an absorbable barrier membrane for guided tissue regeneration which is useful for regeneration of animal tissues, including those of humans, the absorbable barrier membrane being superior in heat stability, processability, reproducibility, storage stability, bioabsorbablity, and tissue regeneration effects, and further provides a method for regeneration, using the absorbable barrier membrane, of a mandible, periodontal tissue, or defective tubulous bone, and particularly a defective tubulous bone which possesses a segmental bone defect in which both ends of the bone are in separate segments. The above objects are attained by an absorbable barrier membrane for use in guided tissue generation, comprising a lactic copolyester in which a polymerization catalyst is deactivated, as an essential component.Type: GrantFiled: March 19, 1998Date of Patent: January 2, 2001Assignee: Director-General of National Institute for Research in Organic MaterialsInventors: Toshiki Shikata, Yasutoshi Kakizawa, Jyunzo Tanaka, Yasushi Suetsugu, Masanori Kikuchi, Hiroo Miyairi, Kazuo Takakuda, Yoshihisa Koyama
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Patent number: 5805513Abstract: A semiconductor memory device is provided which includes a substrate arrangement which is suitable for forming a large number of types of DRAMs having different package specifications, different bit structure and different operating modes. In conjunction with this, the bonding pads are arranged at optimum locations for accommodating the different package types. Various layout arrangements are also provided to minimize space and to improve access time. Additional features are provided, including improved output buffer circuitry, protection circuitry and testing methods to facilitate operation of the semiconductor memory device.Type: GrantFiled: May 2, 1995Date of Patent: September 8, 1998Assignees: Hitachi, Ltd., Hitachi VLSI Engineering Corp.Inventors: Yasushi Takahashi, Hidetoshi Iwai, Satoshi Oguchi, Hisashi Nakamura, Hiroyuki Uchiyama, Toshitugu Takekuma, Shigetoshi Sakomura, Kazuyuki Miyazawa, Masamichi Ishihara, Ryoichi Hori, Takeshi Kizaki, Yoshihisa Koyama, Haruo Ii, Masaya Muranaka, Hidetomo Aoyagi, Hiromi Matsuura
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Patent number: 5598373Abstract: A defect remedy LSI mounted on a memory module, comprising: an input interface portion for capturing address and control signals, the input interface portion being the same as that of a dynamic RAM; an input/output interface portion corresponding to a data bus of a memory device comprised of a plurality of dynamic random access memories; a memory circuit to which a chip address and an X defective address of any of the plurality of random access memories are electrically written, the memory circuit being substantially made nonvolatile; a redundancy remedy RAM portion composed of a static RAM wherein a word line is selected by a compare match signal between an X address signal and the defective address of the memory circuit, the X address signal and the defective address being captured via the input interface portion, and a column is selected by a Y address signal captured via the input interface portion; a selecting portion for connecting a data input/output bus of the redundancy remedy RAM portion to an inputType: GrantFiled: June 7, 1995Date of Patent: January 28, 1997Assignees: Hitachi, Ltd., Hitachi ULSI Engineering Corp.Inventors: Shoji Wada, Kanehide Kenmizaki, Masaya Muranaka, Masahiro Ogata, Hidetomo Aoyagi, Tetsuya Kitame, Masahiro Katayama, Shoji Kubono, Yukihide Suzuki, Makoto Morino, Sinichi Miyatake, Seiichi Shundo, Yoshihisa Koyama, Nobuhiko Ohno
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Patent number: 5440521Abstract: A semiconductor integrated circuit device constituted by a plurality of sets each of which having a pair of memory mats and each memory mat having a plurality of memory cells arranged in a matrix and a sense amplifier, I/O lines for transmitting signals provided by the sense amplifiers, selecting circuitry for selecting either a condition for sending out the signals provided by the sense amplifiers on the I/O lines or a condition for not sending out the same on the I/O lines, and Y-selection lines for transmitting the selection signals. A decoder connected with selection is disposed substantially at the middle of the Y-selection lines. X- and Y-address buffers are disposed close to each other nearer to the center of the chip than X- and Y-redundant circuits. A reference voltage generating circuit is disposed nearer to the edge of the chip than an output buffer circuit. A relief selecting circuit of each memory mat is formed adjacent to a redundant line selecting circuits included in the same memory mat.Type: GrantFiled: August 19, 1993Date of Patent: August 8, 1995Assignees: Hitachi, Ltd., Hitachi VLSI Engineering Corp., Hitachi Hokkai Semiconductor, Ltd.Inventors: Manabu Tsunozaki, Kyoko Ishii, Koichi Nozaki, Hiroshi Yoshioka, Yoshihisa Koyama, Shinji Udo, Hidetomo Aoyagi, Sinichi Miyatake, Makoto Morino, Akihiko Hoshida
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Patent number: 5430705Abstract: In an information recording apparatus, light containing information to be recorded is generated, and a photo-to-electric converting device serves to convert the light into a charge latent image. The photo-to-electric converting device includes a photoconductive member exposed to the light. Information corresponding to the charge latent image is recorded on a recording medium. A first recording device serves to record main information on a first region of the recording medium. A second recording device separate from the first recording device serves to record sub information on a second region of the recording medium. The second region is different from the first region.Type: GrantFiled: March 28, 1991Date of Patent: July 4, 1995Assignee: Victor Company of Japan, Ltd.Inventors: Itsuo Takanashi, Shintaro Nakagaki, Tsutou Asakura, Masato Furuya, Yoshihisa Koyama, Yuji Uchiyama
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Patent number: 5426613Abstract: A semiconductor memory device is provided which includes a substrate arrangement which is suitable for forming a large number of types of DRAMs having different package specifications, different bit structure and different operating modes. In conjunction with this, the bonding pads are arranged at optimum locations for accommodating the different package types. Various layout arrangements are also provided to minimize space and to improve access time. Additional features are provided, including improved output buffer circuitry, protection circuitry and testing methods to facilitate operation of the semiconductor memory device.Type: GrantFiled: November 6, 1992Date of Patent: June 20, 1995Assignees: Hitachi, Ltd., Hitachi VLSI Engineering Corp.Inventors: Yasushi Takahashi, Hidetoshi Iwai, Satoshi Oguchi, Hisashi Nakamura, Hiroyuki Uchiyama, Toshitugu Takekuma, Shigetoshi Sakomura, Kazuyuki Miyazawa, Masamichi Ishihara, Ryoichi Hori, Takeshi Kizaki, Yoshihisa Koyama, Haruo Ii, Masaya Muranaka, Hidetomo Aoyagi, Hiromi Matsuura
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Patent number: 5422663Abstract: An image formation apparatus using a recording medium including a scattering-mode light-modulation member which takes an opaque state in response to a heat and takes a transparent state in response to an electric field. The apparatus comprises an electrode device disposed in opposed relation to the recording medium and a charge removal device facing or in contact with the recording medium. The electrode device applies an electric field to the recording medium thereby completely erasing an image previously recorded in the recording medium and the charge removal device removes charge left in the recording medium due to application of the electric field by the electrode device. After the erasure, the recording medium is heated by a thermal head in accordance with an information signal from an external device so as to form a new image in the recording medium.Type: GrantFiled: March 31, 1994Date of Patent: June 6, 1995Assignee: Victor Company Of Japan, Ltd.Inventors: Itsuo Takanashi, Shintaro Nakagaki, Tsutou Asakura, Yoshihisa Koyama, Hiroyuki Bonde
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Patent number: 5408341Abstract: A system has a first electrode, a second electrode, a photosensitive member located between the first and second electrodes, a recording member located between the first and second electrodes, and an optical shutter. In this system, light having information to be recorded is applied to the photosensitive member. The light information is recorded on the recording member. An exposure amount of the light with respect to the photosensitive member is set by setting a time during which the optical shutter remains open. A drive voltage of a predetermined variation is applied between the first and second electrodes during the recording of the light information on the recording member. The predetermined voltage between the first and second electrodes is controlled in response to a sensed intensity of reference light which passes through the photo-modulation member.Type: GrantFiled: March 28, 1994Date of Patent: April 18, 1995Assignee: Victor Company of Japan, Ltd.Inventors: Itsuo Takanashi, Shintaro Nakagaki, Tsutou Asakura, Masato Furuya, Yoshihisa Koyama, Yuji Uchiyama
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Patent number: 5406095Abstract: An LED (light emitting diode) array of the present invention has a plurality of light emitting diodes aligned in row on a substrate crystal. Each of the light emitting diodes has a double hetero-structure formed by causing a light emitting layer to be interposed between p-type and n-type semi-conductive layers and is isolated with isolating mesa grooves. A reflecting layer is provided between the substrate crystal and one of the p-type and n-type semi-conductive layers. The reflecting layer comprises a plurality of semi-conductive layers having at least different refractive indexes of 2 or more than 2-kinds, each of the semi-conductive layers made of semiconductor having the same polarity as that of the substrate crystal and having a wider forbidden band width than that of the light emitting layer. Further, the isolating mesa grooves are provided by a wet etching using an etching liquid of H.sub.3 PO.sub.4 .multidot.H.sub.2 O.sub.2 having volume ratio of H.sub.3 PO.sub.4 : H.sub.2 O.sub.2 =1.about.Type: GrantFiled: August 26, 1993Date of Patent: April 11, 1995Assignee: Victor Company of Japan, Ltd.Inventors: Yoshihisa Koyama, Taku Katayama, Katsuhiko Morita, Masashi Yoshimura, Toshiki Yoshida, Manabu Endo
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Patent number: 5367359Abstract: A plate-making apparatus equipped with an optical system and a light-light transforming device comprising a photoconductive layer and a light-modulation layer which are in confronting relation to each other and which are interposed between a pair of electrodes. The optical system supplies optical information to the photoconductive layer, and the pair of electrodes are for generating an electric field therebetween to be applied to the photosensitive layer and the light-modulation layer. Also included in the apparatus for emitting light having a predetermined wavelength, the light being led to the light-modulation layer to generate reflection light therefrom which is modulated in correspondance with the optical information supplied from the optical system to the photoconductive layer. The reflection light is arranged so as to illuminate a photosensitive resin layer, which is in turn denatured or hardened in response to the illumination so as to produce a print plate.Type: GrantFiled: April 19, 1993Date of Patent: November 22, 1994Assignee: Victor Company of Japan, Ltd.Inventors: Itsuo Takanashi, Shintaro Nakagaki, Tsutou Asakura, Masato Furuya, Yoshihisa Koyama, Yuji Uchiyama
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Patent number: 5337078Abstract: An apparatus for recording information carried by an electro-magnetic radiation beam. The apparatus has a recording unit having two electrodes, a photoconductive member and a recording member of liquid crystals capable of holding electric charges, the members being arranged so as to face each other between the electrodes. An electro-magnetic radiation beam carrying information to be recorded is directed to the photoconductive member under presence of a voltage across the electrodes. An electric field corresponding to a conductivity variation of the photoconductive member according to the information is thus applied to the recording member to form a charge latent image corresponding to the information on the recording member. The recording member is then heated so that an intensity of the applied electric field exceeds a specific threshold level at which an optical characteristic of the liquid crystal begins to vary according to the charge latent image.Type: GrantFiled: May 21, 1992Date of Patent: August 9, 1994Assignee: Victor Company of Japan, Ltd.Inventors: Itsuo Takanashi, Shintaro Nakagaki, Tsutou Asakura, Masato Furuya, Yoshihisa Koyama, Yuji Uchiyama
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Patent number: 5319461Abstract: A recording medium is formed by laminating a first transparent electrode, a photoconductive layer member, a recording member and a second transparent electrode in order. The recording medium has voltage supply members, having a conductive material, being provided to peripheral portions of the electrodes, equalizing electric potentials of the peripheral portions respectively when a specific voltage is applied across the electrodes, to make currents flow from the peripheral portions to respective portions of the electrodes, thus a potential difference between the electrodes, thus a potential difference between the electrodes being constant. There is also a recording medium having first and second transparent electrodes, a photoconductive layer member and a recording member.Type: GrantFiled: March 4, 1992Date of Patent: June 7, 1994Assignee: Victor Company of Japan, Ltd.Inventors: Itsuo Takanashi, Shintaro Nakagaki, Tsutou Asakura, Masato Furuya, Yoshihisa Koyama, Yuji Uchiyama
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Patent number: 5315410Abstract: A system has a first electrode, a second electrode, a photosensitive member located between the first and second electrodes, a recording member located between the first and second electrodes, and an optical shutter. In this system, light having information to be recorded is applied to the photosensitive member. The light information is recorded on the recording member. An exposure amount of the light with respect to the photosensitive member is set by setting a time during which the optical shutter remains open. A drive voltage of a predetermined variation manner is applied between the first and second electrodes during the recording of the light information on the recording member.Type: GrantFiled: February 8, 1991Date of Patent: May 24, 1994Assignee: Victor Company of Japan, Ltd.Inventors: Itsuo Takanshi, Shintaro Nakagaki, Tsutou Asakura, Masato Furuya, Yoshihisa Koyama, Yuji Uchiyama
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Patent number: 5315318Abstract: An image formation apparatus using a recording medium including a scattering-mode light-modulation member which takes an opaque state in response to a heat and takes a transparent state in response to an electric field. The apparatus comprises a heater and an electrode device which are disposed in opposed relation to the recording medium. The heater preheats the recording medium in accordance with a control signal from an external device and the electrode device applies an electric field to the recording medium after the heating, thereby completely erasing an image previously recorded in the recording medium. After the erasure, the recording medium is heated by a thermal head in accordance with an information signal from an external device so as to form a new image in the recording medium.Type: GrantFiled: February 26, 1992Date of Patent: May 24, 1994Assignee: Victor Company of Japan, Ltd.Inventors: Itsuo Takanashi, Shintaro Nakagaki, Tsutou Asakura, Yoshihisa Koyama, Hiroyuki Bonde
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Patent number: 5313288Abstract: A recording medium has first and second transparent electrodes, a photoconductive layer member and a photomodulation member. The recordingmedium also has a first lamination member having a first substrate on which the first transparent electrode and the photoconductive layer member are laminated in order, a second lamination member having a second transparent substrate on which the second transparent electrode and the photomodulation layer member are laminated in order and coupling members for unifying the first and second lamination members together with a gap of specific width in such a manner that the photoconductive and photomodulation layer members face each other.Type: GrantFiled: March 4, 1992Date of Patent: May 17, 1994Assignee: Victor Company of Japan, Ltd.Inventors: Itsuo Takanashi, Shintaro Nakagaki, Tsutou Asakura, Masato Furuya, Yoshihisa Koyama, Yuji Uchiyama