Patents by Inventor Yoshihisa TOMIOKA

Yoshihisa TOMIOKA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Marker for determining diabetic nephropathy
    Patent number: 10802031
    Abstract: An object of the present invention is to provide a biomarker capable of determining the onset risk or the stage of diabetic nephropathy (early-stage diabetic nephropathy in particular). Diabetic nephropathy is determined by measuring or quantitatively determining a concentration of phenyl sulfate or a salt thereof (a phenyl sulfate) contained in a biological sample, preferably plasma or urine, collected from a test subject to detect a phenyl sulfate. The present invention exhibits excellent effects particularly for stage determination for stage 1 (pre-nephropathy stage) to stage 3 (overt nephropathy stage), or for determination of onset risk of diabetic nephropathy (diabetic nephropathy at pre-nephropathy stage).
    Type: Grant
    Filed: September 29, 2016
    Date of Patent: October 13, 2020
    Assignee: TOHOKU UNIVERSITY
    Inventors: Takaaki Abe, Susumu Ogawa, Yoshihisa Tomioka
  • MARKER FOR DETERMINING DIABETIC NEPHROPATHY
    Publication number: 20180313851
    Abstract: An object of the present invention is to provide a biomarker capable of determining the onset risk or the stage of diabetic nephropathy (early-stage diabetic nephropathy in particular). Diabetic nephropathy is determined by measuring or quantitatively determining a concentration of phenyl sulfate or a salt thereof (a phenyl sulfate) contained in a biological sample, preferably plasma or urine, collected from a test subject to detect a phenyl sulfate. The present invention exhibits excellent effects particularly for stage determination for stage 1 (pre-nephropathy stage) to stage 3 (overt nephropathy stage), or for determination of onset risk of diabetic nephropathy (diabetic nephropathy at pre-nephropathy stage).
    Type: Application
    Filed: September 29, 2016
    Publication date: November 1, 2018
    Inventors: Takaaki ABE, Susumu OGAWA, Yoshihisa TOMIOKA