Patents by Inventor Yoshikatsu Izumi

Yoshikatsu Izumi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FUSION PROTEIN CONTAINING ERYTHROPOIETIN POLYPEPTIDE
    Publication number: 20230357341
    Abstract: The present invention relates to a fusion protein containing an erythropoietin polypeptide fused to the Fc region of mammal-derived IgG (hereinafter to be also abbreviated as EPO-Fc fusion protein). The fusion protein in which erythropoietin polypeptide has the amino acid sequence shown in SEQ ID NO: 9 or 10, and the Fc region has the amino acid sequence shown in SEQ ID NO: 3 or 4 is more superior in the property and activity and can be obtained at a high yield.
    Type: Application
    Filed: June 9, 2021
    Publication date: November 9, 2023
    Applicant: BICA THERAPEUTICS INC.
    Inventors: Ryota NAKAO, Yoshikatsu IZUMI, Kunihiro HATTORI
  • MODIFIED PRODUCT OF FC DOMAIN OF ANTIBODY
    Publication number: 20220048981
    Abstract: The present invention is directed to a variant of a parent polypeptide containing an Fc region of a dog or cat IgG, that shows a higher binding activity to a dog or cat neonatal Fc receptor (FcRn) than a binding activity of the parent polypeptide to a dog or cat FcRn, wherein the Fc region contains at least one amino acid modification. The variant shows an enhanced FcRn binding activity under acidic conditions. Using the variant, therefore, an antibody (IgG) and Fc fusion protein having longer retention in plasma can be provided.
    Type: Application
    Filed: December 5, 2019
    Publication date: February 17, 2022
    Inventors: Ryota Nakao, Yoshikatsu Izumi, Kunihiro Hattori