Patents by Inventor Yoshikatsu Kodama

Yoshikatsu Kodama has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20060182730
    Abstract: Objects of the present invention are to provide an agent for inhibiting a digestive enzymes and an antiobesity agent having digestive-enzyme-inhibiting activity with high substrate specificity and having high safety. Provided is a composition comprising eggs produced by hens immunized with digestive enzymes or fragments thereof, or the processed products thereof, and containing 2 or more types of digestive enzymes.
    Type: Application
    Filed: July 7, 2004
    Publication date: August 17, 2006
    Inventors: Yoshikatsu Kodama, Hideo Goshima
  • Publication number: 20060057150
    Abstract: Prevention and treatment of coccidiosis in chicken is accomplished by administering an anti-chicken coccidiosis composition adapted for oral administration. This composition contains an antibody obtained from an egg of a chicken immunized with an antigenic outermembrane protein or an immunogenic fragment thereof as an antigen having an immunogenicity common for sporozoit and merozoite of Eimeria acervulina, Eimeria tenella, and Eimeria maxima which are associated with chicken coccidiosis. The composition may optionally contain a lactic acid bacterium and/or an antibody obtained from an egg of a chicken immunized with Clostridium perfringens.
    Type: Application
    Filed: June 26, 2003
    Publication date: March 16, 2006
    Applicant: GHEN CORPORATION
    Inventors: Yoshikatsu Kodama, Hideaki Yokoyama, Sa Nguyen
  • Publication number: 20050096262
    Abstract: This invention relates to a Helicobacter pylori adhesion inhibitor that is capable of eliminating Helicobacter pylori associated with the development of peptic ulcer from the stomach, a method for producing the same, and pharmaceutical compositions and foods for preventing or treating diseases associated with Helicobacter pylori comprising such Helicobacter pylori adhesion inhibitor. The inhibitor of the present invention has excellent activity of eradicating Helicobacter pylori and is highly safe. Accordingly, pharmaceutical compositions and foods comprising the same are highly useful for the prevention or treatment of the aforementioned diseases.
    Type: Application
    Filed: January 27, 2003
    Publication date: May 5, 2005
    Inventors: Shigeru Hiramoto, Yoshiro Morishita, Nobutake Kimura, Yoshikatsu Kodama
  • Patent number: 6828298
    Abstract: An inhibitor of Helicobacter pylori colonization in the stomach comprises as an active ingredient a glycoprotein which specifically binds to H. pylori urease. This glycoprotein is isolated and purified from a glycoprotein-containing substance, especially that derived from bovine milk whey or albumen of chicken eggs by affinity chromatography using a column on which H. pylori urease is immobilized. The glycoprotein is able to effectively inhibit H. pylori colonization, so is useful for the prevention or treatment of diseases caused by infection of H. pylori such as peptic ulcers. A food and medicament comprising the inhibitor are also provided.
    Type: Grant
    Filed: April 13, 2001
    Date of Patent: December 7, 2004
    Assignees: Ghen Corporation, Nisshin Pharma Inc.
    Inventors: Yoshikatsu Kodama, Nobutake Kimura
  • Patent number: 6797268
    Abstract: An inhibitor composition of Helicobacter pylori adhesion in the stomach comprises (1) anti-urease antibodies obtained from eggs laid by hens which have been immunized against H. pylori urease and (2) an inhibitor of gastric acid secretion. This inhibitor is capable of completely eliminating H. pylori from the stomach, so it is useful for the prevention or treatment of diseases caused by infection of H. pylori such as peptic ulcers.
    Type: Grant
    Filed: July 13, 2001
    Date of Patent: September 28, 2004
    Assignees: Ghen Corporation, Nisshin Pharma Inc.
    Inventors: Yoshikatsu Kodama, Nobutake Kimura
  • Patent number: 6793921
    Abstract: The present invention provides specific antibodies obtained from eggs laid by hens which have been immunized against urease of Helicobacter pylori as an antigen, and specific antibodies obtained from eggs laid by hens which have been immunized against flagella of Helicobacter pylori as an antigen. These antibodies are useful for the prevention or treatment of gastritis, gastric ulcers and duodenal ulcers caused by infection of Helicobacter pylori. At least one organism selected from lactic acid bacteria, Enterococcuses, yeasts, and Baillus can be used along with the antibodies.
    Type: Grant
    Filed: June 24, 2002
    Date of Patent: September 21, 2004
    Assignees: Nisshin Pharma Inc., Ghen Corporation
    Inventors: Yoshikatsu Kodama, Faustino C. Icatlo, Jr., Nobutake Kimura, Masato Ariga
  • Publication number: 20020197259
    Abstract: The present invention provides specific antibodies obtained from eggs laid by hens which have been immunized against urease of Helicobacter pylori as an antigen, and specific antibodies obtained from eggs laid by hens which have been immunized against flagella of Helicobacter pylori as an antigen. These antibodies are useful for the prevention or treatment of gastritis, gastric ulcers and duodenal ulcers caused by infection of Helicobacter pylori. At least one organism selected from lactic acid bacteria, Enterococcuses, yeasts, and Baillus can be used along with the antibodies.
    Type: Application
    Filed: June 24, 2002
    Publication date: December 26, 2002
    Inventors: Yoshikatsu Kodama, Faustino C. Icatlo, Nobutake Kimura, Masato Ariga
  • Patent number: 6419926
    Abstract: The present invention provides specific antibodies obtained from eggs laid by hens which have been immunized against urease of Helicobacter pylori as an antigen, and specific antibodies obtained from eggs laid by hens which have been immunized against flagella of Helicobacter pylori as an antigen. These antibodies are useful for the prevention or treatment of gastritis, gastric ulcers and duodenal ulcers caused by infection of Helicobacter pylori . At least one organism selected from lactic acid bacteria, Enterococcuses, yeasts, and Baillus can be used along with the antibodies.
    Type: Grant
    Filed: April 8, 1998
    Date of Patent: July 16, 2002
    Assignees: Ghen Corporation, Nisshin Pharma Inc.
    Inventors: Yoshikatsu Kodama, Faustino C. Icatlo, Jr., Nobutake Kimura, Masato Ariga
  • Publication number: 20020039579
    Abstract: An inhibitor composition of Helicobacter pylori adhesion in the stomach comprises (1) anti-urease antibodies obtained from eggs laid by hens which have been immunized against H. pylori urease and (2) an inhibitor of gastric acid secretion. This inhibitor is capable of completely eliminating H. pylori from the stomach, so it is useful for the prevention or treatment of diseases caused by infection of H. pylori such as peptic ulcers.
    Type: Application
    Filed: July 13, 2001
    Publication date: April 4, 2002
    Inventors: Yoshikatsu Kodama, Nobutake Kimura
  • Publication number: 20010044120
    Abstract: An inhibitor of Helicobacter pylori colonization in the stomach comprises as an active ingredient a glycoprotein which specifically binds to H. pylori urease. This glycoprotein is isolated and purified from a glycoprotein-containing substance, especially that derived from bovine milk whey or albumen of chicken eggs by affinity chromatography using a column on which H. pylori urease is immobilized. The glycoprotein is able to effectively inhibit H. pylori colonization, so is useful for the prevention or treatment of diseases caused by infection of H. pylori such as peptic ulcers. A food and medicament comprising the inhibitor are also provided.
    Type: Application
    Filed: April 13, 2001
    Publication date: November 22, 2001
    Inventors: Yoshikatsu Kodama, Nobutake Kimura
  • Publication number: 20010021393
    Abstract: The present invention provides specific antibodies obtained from eggs laid by hens which have been immunized against urease of Helicobacter pylori as an antigen, and specific antibodies obtained from eggs laid by hens which have been immunized against flagella of Helicobacter pylori as an antigen. These antibodies are useful for the prevention or treatment of gastritis, gastric ulcers and duodenal ulcers caused by infection of Helicobacter pylori. At least one organism selected from lactic acid bacteria, Enterococcuses, yeasts, and Baillus can be used along with the antibodies.
    Type: Application
    Filed: April 8, 1998
    Publication date: September 13, 2001
    Inventors: YOSHIKATSU KODAMA, FAUSTINO C. ICATLO, NOBUTAKE KIMURA, MASATO ARIGA
  • Patent number: 6235709
    Abstract: The present invention provides a safe and effective inhibitor of Helicobacter pylori colonization in the stomach and a food containing the inhibitor. The inhibitor of the present invention comprises as an active ingredient a mucin, especially a mucin from milk of a cow or a mucin from albumen of an egg and is useful for the prevention or treatment of diseases caused by infection of Helicobacter pylori such as peptic ulcers.
    Type: Grant
    Filed: December 10, 1999
    Date of Patent: May 22, 2001
    Assignee: Ghen Corporation
    Inventors: Yoshikatsu Kodama, Nobutake Kimura
  • Patent number: 5439680
    Abstract: Cell-associated glucosyltransferase of S. mutans serotypes c, e or f producing dental caries was isolated and purified and its characteristics as an enzyme were revealed. Furthermore, an antibody against said enzyme was prepared from eggs of the hens immunized with said enzyme. Since this antibody effectively prevents adherence of the aforementioned S. mutans to tooth surfaces, it is useful as an effective component for a dental caries prophylactic composition.
    Type: Grant
    Filed: December 2, 1994
    Date of Patent: August 8, 1995
    Assignees: Kanebo Ltd., Ghen Corporation
    Inventors: Toshio Horikoshi, Junichiro Hiraoka, Isamu Fujita, Tohru Tokoro, Yoshikatsu Kodama, Hideaki Yokoyama
  • Patent number: 5281524
    Abstract: Cell-associated glycosyltranferase of S. mutans serotypes c, e or f producing dental caries was isolated and purified and its characteristics as an enzyme were revealed. Furthermore, an antibody against the enzyme was prepared from eggs of the hens immunized with the enzyme. Since this antibody effectively prevents adherence of the aforementioned S. mutans to tooth surfaces, it is useful as an effective component for a dental caries prophylactic composition.
    Type: Grant
    Filed: December 17, 1991
    Date of Patent: January 25, 1994
    Assignees: Kanebo, Ltd., Ghen Corporation
    Inventors: Toshio Horikoshi, Junichiro Hiraoka, Isamu Fujita, Tohru Tokoro, Yoshikatsu Kodama, Hideaki Yokoyama