Patents by Inventor Yoshikatsu Miwa
Yoshikatsu Miwa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9155751Abstract: The objective of the invention is to provide a solution for tissue adhesion prevention and a method for tissue adhesion prevention that are applicable to general surgery and in which covering condition during surgery is stable and convenient. The invention is the solution for tissue adhesion prevention of which the active ingredient is trehalose. Also, it contains at least one or more among antioxidants, chelates, antiseptics, hemostatics, anti-inflammatory agents, and polysaccharides, mucopolysaccharides, salts of polysaccharides and salts of mucopolysaccharides having lubricating properties. This solution for tissue adhesion prevention is provided as any form of perfusion fluid, spray fluid, solution for spray or vaporization administration, foam-like aerosol preparation, injection solution for intravenous fluids, intravenous fluid.Type: GrantFiled: March 14, 2011Date of Patent: October 13, 2015Assignees: THE UNIVERSITY OF TOKYO, KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO, OTSUKA PHARMACEUTICAL FACTORY, INC.Inventors: Shigeki Suzuki, Yoshikatsu Miwa, Nobuo Sasaki, Yuiichi Tei
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Patent number: 9066968Abstract: The present invention has an object to provide a fluid for peritoneal dialysis with satisfactory body fluid removability, high biocompatibility, and improved storage stability, and the object is attained by a fluid for peritoneal dialysis containing one or more saccharides selected from cyclonigerosylnigerose, cyclomaltosylmaltose, and L-ascorbic acid 2-glucoside.Type: GrantFiled: January 31, 2014Date of Patent: June 30, 2015Assignee: HAYASHIBARA CO. LTDInventors: Hitomi Ohta, Toshiharu Hanaya, Shigeharu Fukuda, Yoshikatsu Miwa, Toshio Miyake
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Publication number: 20140148409Abstract: The present invention has an object to provide a fluid for peritoneal dialysis with satisfactory body fluid removability, high biocompatibility, and improved storage stability, and the object is attained by a fluid for peritoneal dialysis containing one or more saccharides selected from cyclonigerosylnigerose, cyclomaltosylmaltose, and L-ascorbic acid 2-glucoside.Type: ApplicationFiled: January 31, 2014Publication date: May 29, 2014Applicant: HAYASHIBARA CO. LTDInventors: Hitomi OHTA, Toshiharu HANAYA, Shigeharu FUKUDA, Yoshikatsu MIWA, Toshio MIYAKE
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Patent number: 8034353Abstract: An object of the present invention is to provide a peptide vaccine for preventing and/or treating diseases caused by amyloid ?-peptide, such as Alzheimer's disease. The present invention solves the above object by providing a peptide vaccine constructed by inserting a peptide having an amino acid sequence of a cell attachment motif of a cell adhesive molecule to a peptide which consists of a peptide having an amino acid sequence of multiagretope type T-cell epitope, which has been generated immunological memory, or a peptide including the same; an linker peptide; and a peptide having an amino acid sequence of a B cell epitope which is a specific region of amyloid ?-peptide or a peptide including the same.Type: GrantFiled: February 16, 2007Date of Patent: October 11, 2011Assignee: Kabushiki Kaisha Hayashibara Seibutsu Kagaku KenkyujoInventors: Akira Yano, Toshiki Nishizawa, Yoshikatsu Miwa
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Publication number: 20110166089Abstract: The objective of the invention is to provide a solution for tissue adhesion prevention and a method for tissue adhesion prevention that are applicable to general surgery and in which covering condition during surgery is stable and convenient. The invention is the solution for tissue adhesion prevention of which the active ingredient is trehalose. Also, it contains at least one or more among antioxidants, chelates, antiseptics, hemostatics, anti-inflammatory agents, and polysaccharides, mucopolysaccharides, salts of polysaccharides and salts of mucopolysaccharides having lubricating properties. This solution for tissue adhesion prevention is provided as any form of perfusion fluid, spray fluid, solution for spray or vaporization administration, foam-like aerosol preparation, injection solution for intravenous fluids, intravenous fluid.Type: ApplicationFiled: March 14, 2011Publication date: July 7, 2011Applicants: OTSUKA PHARMACEUTICAL FACTORY, INC., KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO, THE UNIVERSITY OF TOKYOInventors: Shigeki SUZUKI, Yoshikatsu MIWA, Nobuo SASAKI, Yuiichi TEI
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Publication number: 20100210589Abstract: An object of the present invention is to provide a means for improving hepatic function of mammals including humans to normal condition. The present invention achieves the above object by providing a hepatic function-improving agent comprising ?-glucosyl-hesperidin as an effective ingredient.Type: ApplicationFiled: April 27, 2010Publication date: August 19, 2010Applicant: Kabushiki Kaisha Kayashibara Seibutsu Kagaku KenkyujoInventors: Hitoshi MITSUZUMI, Mika TAKAMI, Yoshikatsu MIWA, Hiroto CHAEN, Toshio MIYAKE
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Publication number: 20090098061Abstract: The objective of the invention is to provide a solution for tissue adhesion prevention and a method for tissue adhesion prevention that are applicable to general surgery and in which covering condition during surgery is stable and convenient. The invention is the solution for tissue adhesion prevention of which the active ingredient is trehalose. Also, it contains at least one or more among antioxidants, chelates, antiseptics, hemostatics, anti-inflammatory agents, and polysaccharides, mucopolysaccharides, salts of polysaccharides and salts of mucopolysaccharides having lubricating properties. This solution for tissue adhesion prevention is provided as any form of perfusion fluid, spray fluid, solution for spray or vaporization administration, foam-like aerosol preparation, injection solution for intravenous fluids, intravenous fluid.Type: ApplicationFiled: June 8, 2006Publication date: April 16, 2009Applicants: Cellex K.K., KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO, THE UNIVERSITY OF TOKYOInventors: Shigeki Suzuki, Yoshikatsu Miwa, Nobuo Sasaki, Yuiichi Tei
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Publication number: 20090023684Abstract: The present invention has an object to provide a fluid for peritoneal dialysis with satisfactory body fluid removability, high biocompatibility, and improved storage stability, and the object is attained by a fluid for peritoneal dialysis containing one or more saccharides selected from cyclonigerosylnigerose, cyclomaltosylmaltose, and L-ascorbic acid 2-glucoside.Type: ApplicationFiled: April 13, 2006Publication date: January 22, 2009Inventors: Hitomi Ohta, Toshiharu Hanaya, Shigeharu Fukuda, Yoshikatsu Miwa, Toshio Miyake
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Publication number: 20080221045Abstract: An object of the present invention is to provide a means for improving hepatic function of mammals including humans to normal condition. The present invention achieves the above object by providing a hepatic function-improving agent comprising ?-glucosyl-hesperidin as an effective ingredient.Type: ApplicationFiled: November 21, 2005Publication date: September 11, 2008Applicant: Kabushiki Kaisha Hayashibara Seibutsu Kagaku KenkyujoInventors: Hitoshi Mitsuzumi, Mika Takami, Yoshikatsu Miwa, Hiroto Chaen, Toshio Miyake
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Patent number: 7390039Abstract: A bumper absorber for protecting pedestrians is formed into a W-shaped cross-sectional configuration, as taken along a direction which is orthogonal to a longitudinal direction of the bumper absorber. The W-shaped cross sectional configuration has portions in which a front notch portion, an upper rear notch portion, and a lower rear notch portion overlap with one another in a vertical direction of a vehicle. Ribs are formed respectively at the upper rear notch portion and the lower rear notch portion, and a triangular notch is formed from a vehicle rear side at each of the rib. Further, the ribs 30 are formed at the upper rear notch portion and the lower rear notch portion so as to be separated from each other at predetermined intervals in a longitudinal direction of the bumper absorber, namely, in a transverse direction of the vehicle. With this structure, a rise in impact load acting on a pedestrian who is hit by a bumper can be controlled.Type: GrantFiled: April 23, 2007Date of Patent: June 24, 2008Assignees: Sekisui Kaseihin Kogyo Kabushiki Kaisha, Kabushiki Kaisha ChugaiInventors: Junji Adachi, Naruaki Abe, Fumihiko Sato, Taku Fukuyama, Kouji Mori, Yoshikatsu Miwa, Yukiya Morita
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Publication number: 20070187959Abstract: A bumper absorber for protecting pedestrians is formed into a W-shaped cross-sectional configuration, as taken along a direction which is orthogonal to a longitudinal direction of the bumper absorber. The W-shaped cross sectional configuration has portions in which a front notch portion, an upper rear notch portion, and a lower rear notch portion overlap with one another in a vertical direction of a vehicle. Ribs are formed respectively at the upper rear notch portion and the lower rear notch portion, and a triangular notch is formed from a vehicle rear side at each of the rib. Further, the ribs 30 are formed at the upper rear notch portion and the lower rear notch portion so as to be separated from each other at predetermined intervals in a longitudinal direction of the bumper absorber, namely, in a transverse direction of the vehicle. With this structure, a rise in impact load acting on a pedestrian who is hit by a bumper can be controlled.Type: ApplicationFiled: April 23, 2007Publication date: August 16, 2007Applicants: SEKISUI KASEIHIN KOGYO KABUSHIKI KAISHA, KABUSHIKI KAISHA CHUGAIInventors: Junji Adachi, Naruaki Abe, Fumihiko Sato, Taku Fukuyama, Kouji Mori, Yoshikatsu Miwa, Yukiya Morita
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Patent number: 7226097Abstract: A bumper absorber for protecting pedestrians (20) is formed into a W-shaped cross-sectional configuration, as taken along a direction which is orthogonal to a longitudinal direction of the bumper absorber. The W-shaped cross sectional configuration has portions in which a front notch portion (22), an upper rear notch portion (24), and a lower rear notch portion (26) overlap with one another in a vertical direction of a vehicle. Ribs (30) are formed respectively at the upper rear notch portion (24) and the lower rear notch portion (26), and a triangular notch (32) is formed from a vehicle rear side at each of the rib (30). Further, the ribs 30 are formed at the upper rear notch portion (24) and the lower rear notch portion (26) so as to be separated from each other at predetermined intervals in a longitudinal direction of the bumper absorber, namely, in a transverse direction of the vehicle. With this structure, a rise in impact load acting on a pedestrian who is hit by a bumper can be controlled.Type: GrantFiled: September 30, 2003Date of Patent: June 5, 2007Assignees: Sekisui Kaseihin Kogyo Kabushiki Kaisha, Kabushiki Kaisha ChugaiInventors: Junji Adachi, Naruaki Abe, Fumihiko Sato, Taku Fukuyama, Kouji Mori, Yoshikatsu Miwa, Yukiya Morita
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Publication number: 20060131899Abstract: A bumper absorber for protecting pedestrians (20) is formed into a W-shaped cross-sectional configuration, as taken along a direction which is orthogonal to a longitudinal direction of the bumper absorber. The W-shaped cross sectional configuration has portions in which a front notch portion (22), an upper rear notch portion (24), and a lower rear notch portion (26) overlap with one another in a vertical direction of a vehicle. Ribs (30) are formed respectively at the upper rear notch portion (24) and the lower rear notch portion (26), and a triangular notch (32) is formed from a vehicle rear side at each of the rib (30). Further, the ribs 30 are formed at the upper rear notch portion (24) and the lower rear notch portion (26) so as to be separated from each other at predetermined intervals in a longitudinal direction of the bumper absorber, namely, in a transverse direction of the vehicle. With this structure, a rise in impact load acting on a pedestrian who is hit by a bumper can be controlled.Type: ApplicationFiled: September 30, 2003Publication date: June 22, 2006Inventors: Junji Adachi, Naruaki Abe, Fumihiko Sato, Taku Fukuyama, Kouji Mori, Yoshikatsu Miwa, Yukiya Morita
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Patent number: 5942224Abstract: A method using a therapeutic agent for cat respiratory diseases which contains a human interferon as an effective ingredient. The therapeutic agent exerts a strong efficacy on cats with only a small dose even if administered to them orally or parenterally, and reduces the labor and burden of veterinaries and cat owners by a large margin.Type: GrantFiled: December 22, 1995Date of Patent: August 24, 1999Assignee: Kabushiki Kaisha Hayashibara Seibutsu Kagaku KenkyujoInventors: Yoshikatsu Miwa, Takatoshi Tamura, Hitoshi Murasaki, Masakazu Mitsuhashi
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Patent number: 5714476Abstract: Neotrehalose is prepared in a relatively high-yield by a process comprising allowing .beta.-galactosidase to act on a solution containing lactoneotrehalose to form neotrehalose and recoverying the resultant neotrehalose. The neotrehalose is a non-reducing oligosaccharide having a satisfiable stability and a rich- and high-quality-sweetness and is assimilated and utilized as energy source in vivo when orally administered. Neotrehalose in the form of crystal has a satisfiable handleability because it is readily soluble in water and substantially free of hygroscopicity. These render neotrehalose very useful in the fields of food-, cosmetic- and pharmaceutical-industries.Type: GrantFiled: September 30, 1994Date of Patent: February 3, 1998Assignee: Kabushiki Kaisha Hayashibara Seibutsu Kagaku KenkyujoInventors: Yoshikatsu Miwa, Takashi Shibuya, Hiroto Chaen
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Patent number: 5403727Abstract: Neotrehalose is prepared in a relatively high-yield by a process comprising allowing .beta.-galactosidase to act on a solution containing lactoneotrehalose to form neotrehalose and recovering the resultant neotrehalose. The neotrehalose is a non-reducing oligosaccharide having a satisfiable stability and a rich- and high-quality-sweetness and is assimilated and utilized as energy source in vivo when orally administered. Neotrehalose in the form of crystal has a satisfiable handleability because it is readily soluble in water and substantially free of hygroscopicity. These render neotrehalose very useful in the fields of food-, cosmetic- and pharmaceutical-industries.Type: GrantFiled: May 2, 1994Date of Patent: April 4, 1995Assignee: Kabushiki Kaisha Hayashibara Seibutsu Kagaku KenkyujoInventors: Yoshikatsu Miwa, Takashi Shibuya, Hiroto Chaen