Patents by Inventor Yoshikatsu Miwa

Yoshikatsu Miwa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9155751
    Abstract: The objective of the invention is to provide a solution for tissue adhesion prevention and a method for tissue adhesion prevention that are applicable to general surgery and in which covering condition during surgery is stable and convenient. The invention is the solution for tissue adhesion prevention of which the active ingredient is trehalose. Also, it contains at least one or more among antioxidants, chelates, antiseptics, hemostatics, anti-inflammatory agents, and polysaccharides, mucopolysaccharides, salts of polysaccharides and salts of mucopolysaccharides having lubricating properties. This solution for tissue adhesion prevention is provided as any form of perfusion fluid, spray fluid, solution for spray or vaporization administration, foam-like aerosol preparation, injection solution for intravenous fluids, intravenous fluid.
    Type: Grant
    Filed: March 14, 2011
    Date of Patent: October 13, 2015
    Assignees: THE UNIVERSITY OF TOKYO, KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO, OTSUKA PHARMACEUTICAL FACTORY, INC.
    Inventors: Shigeki Suzuki, Yoshikatsu Miwa, Nobuo Sasaki, Yuiichi Tei
  • Patent number: 9066968
    Abstract: The present invention has an object to provide a fluid for peritoneal dialysis with satisfactory body fluid removability, high biocompatibility, and improved storage stability, and the object is attained by a fluid for peritoneal dialysis containing one or more saccharides selected from cyclonigerosylnigerose, cyclomaltosylmaltose, and L-ascorbic acid 2-glucoside.
    Type: Grant
    Filed: January 31, 2014
    Date of Patent: June 30, 2015
    Assignee: HAYASHIBARA CO. LTD
    Inventors: Hitomi Ohta, Toshiharu Hanaya, Shigeharu Fukuda, Yoshikatsu Miwa, Toshio Miyake
  • Publication number: 20140148409
    Abstract: The present invention has an object to provide a fluid for peritoneal dialysis with satisfactory body fluid removability, high biocompatibility, and improved storage stability, and the object is attained by a fluid for peritoneal dialysis containing one or more saccharides selected from cyclonigerosylnigerose, cyclomaltosylmaltose, and L-ascorbic acid 2-glucoside.
    Type: Application
    Filed: January 31, 2014
    Publication date: May 29, 2014
    Applicant: HAYASHIBARA CO. LTD
    Inventors: Hitomi OHTA, Toshiharu HANAYA, Shigeharu FUKUDA, Yoshikatsu MIWA, Toshio MIYAKE
  • Patent number: 8034353
    Abstract: An object of the present invention is to provide a peptide vaccine for preventing and/or treating diseases caused by amyloid ?-peptide, such as Alzheimer's disease. The present invention solves the above object by providing a peptide vaccine constructed by inserting a peptide having an amino acid sequence of a cell attachment motif of a cell adhesive molecule to a peptide which consists of a peptide having an amino acid sequence of multiagretope type T-cell epitope, which has been generated immunological memory, or a peptide including the same; an linker peptide; and a peptide having an amino acid sequence of a B cell epitope which is a specific region of amyloid ?-peptide or a peptide including the same.
    Type: Grant
    Filed: February 16, 2007
    Date of Patent: October 11, 2011
    Assignee: Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo
    Inventors: Akira Yano, Toshiki Nishizawa, Yoshikatsu Miwa
  • Publication number: 20110166089
    Abstract: The objective of the invention is to provide a solution for tissue adhesion prevention and a method for tissue adhesion prevention that are applicable to general surgery and in which covering condition during surgery is stable and convenient. The invention is the solution for tissue adhesion prevention of which the active ingredient is trehalose. Also, it contains at least one or more among antioxidants, chelates, antiseptics, hemostatics, anti-inflammatory agents, and polysaccharides, mucopolysaccharides, salts of polysaccharides and salts of mucopolysaccharides having lubricating properties. This solution for tissue adhesion prevention is provided as any form of perfusion fluid, spray fluid, solution for spray or vaporization administration, foam-like aerosol preparation, injection solution for intravenous fluids, intravenous fluid.
    Type: Application
    Filed: March 14, 2011
    Publication date: July 7, 2011
    Applicants: OTSUKA PHARMACEUTICAL FACTORY, INC., KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO, THE UNIVERSITY OF TOKYO
    Inventors: Shigeki SUZUKI, Yoshikatsu MIWA, Nobuo SASAKI, Yuiichi TEI
  • Publication number: 20100210589
    Abstract: An object of the present invention is to provide a means for improving hepatic function of mammals including humans to normal condition. The present invention achieves the above object by providing a hepatic function-improving agent comprising ?-glucosyl-hesperidin as an effective ingredient.
    Type: Application
    Filed: April 27, 2010
    Publication date: August 19, 2010
    Applicant: Kabushiki Kaisha Kayashibara Seibutsu Kagaku Kenkyujo
    Inventors: Hitoshi MITSUZUMI, Mika TAKAMI, Yoshikatsu MIWA, Hiroto CHAEN, Toshio MIYAKE
  • Publication number: 20090098061
    Abstract: The objective of the invention is to provide a solution for tissue adhesion prevention and a method for tissue adhesion prevention that are applicable to general surgery and in which covering condition during surgery is stable and convenient. The invention is the solution for tissue adhesion prevention of which the active ingredient is trehalose. Also, it contains at least one or more among antioxidants, chelates, antiseptics, hemostatics, anti-inflammatory agents, and polysaccharides, mucopolysaccharides, salts of polysaccharides and salts of mucopolysaccharides having lubricating properties. This solution for tissue adhesion prevention is provided as any form of perfusion fluid, spray fluid, solution for spray or vaporization administration, foam-like aerosol preparation, injection solution for intravenous fluids, intravenous fluid.
    Type: Application
    Filed: June 8, 2006
    Publication date: April 16, 2009
    Applicants: Cellex K.K., KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO, THE UNIVERSITY OF TOKYO
    Inventors: Shigeki Suzuki, Yoshikatsu Miwa, Nobuo Sasaki, Yuiichi Tei
  • Publication number: 20090023684
    Abstract: The present invention has an object to provide a fluid for peritoneal dialysis with satisfactory body fluid removability, high biocompatibility, and improved storage stability, and the object is attained by a fluid for peritoneal dialysis containing one or more saccharides selected from cyclonigerosylnigerose, cyclomaltosylmaltose, and L-ascorbic acid 2-glucoside.
    Type: Application
    Filed: April 13, 2006
    Publication date: January 22, 2009
    Inventors: Hitomi Ohta, Toshiharu Hanaya, Shigeharu Fukuda, Yoshikatsu Miwa, Toshio Miyake
  • Publication number: 20080221045
    Abstract: An object of the present invention is to provide a means for improving hepatic function of mammals including humans to normal condition. The present invention achieves the above object by providing a hepatic function-improving agent comprising ?-glucosyl-hesperidin as an effective ingredient.
    Type: Application
    Filed: November 21, 2005
    Publication date: September 11, 2008
    Applicant: Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo
    Inventors: Hitoshi Mitsuzumi, Mika Takami, Yoshikatsu Miwa, Hiroto Chaen, Toshio Miyake
  • Patent number: 7390039
    Abstract: A bumper absorber for protecting pedestrians is formed into a W-shaped cross-sectional configuration, as taken along a direction which is orthogonal to a longitudinal direction of the bumper absorber. The W-shaped cross sectional configuration has portions in which a front notch portion, an upper rear notch portion, and a lower rear notch portion overlap with one another in a vertical direction of a vehicle. Ribs are formed respectively at the upper rear notch portion and the lower rear notch portion, and a triangular notch is formed from a vehicle rear side at each of the rib. Further, the ribs 30 are formed at the upper rear notch portion and the lower rear notch portion so as to be separated from each other at predetermined intervals in a longitudinal direction of the bumper absorber, namely, in a transverse direction of the vehicle. With this structure, a rise in impact load acting on a pedestrian who is hit by a bumper can be controlled.
    Type: Grant
    Filed: April 23, 2007
    Date of Patent: June 24, 2008
    Assignees: Sekisui Kaseihin Kogyo Kabushiki Kaisha, Kabushiki Kaisha Chugai
    Inventors: Junji Adachi, Naruaki Abe, Fumihiko Sato, Taku Fukuyama, Kouji Mori, Yoshikatsu Miwa, Yukiya Morita
  • Publication number: 20070187959
    Abstract: A bumper absorber for protecting pedestrians is formed into a W-shaped cross-sectional configuration, as taken along a direction which is orthogonal to a longitudinal direction of the bumper absorber. The W-shaped cross sectional configuration has portions in which a front notch portion, an upper rear notch portion, and a lower rear notch portion overlap with one another in a vertical direction of a vehicle. Ribs are formed respectively at the upper rear notch portion and the lower rear notch portion, and a triangular notch is formed from a vehicle rear side at each of the rib. Further, the ribs 30 are formed at the upper rear notch portion and the lower rear notch portion so as to be separated from each other at predetermined intervals in a longitudinal direction of the bumper absorber, namely, in a transverse direction of the vehicle. With this structure, a rise in impact load acting on a pedestrian who is hit by a bumper can be controlled.
    Type: Application
    Filed: April 23, 2007
    Publication date: August 16, 2007
    Applicants: SEKISUI KASEIHIN KOGYO KABUSHIKI KAISHA, KABUSHIKI KAISHA CHUGAI
    Inventors: Junji Adachi, Naruaki Abe, Fumihiko Sato, Taku Fukuyama, Kouji Mori, Yoshikatsu Miwa, Yukiya Morita
  • Patent number: 7226097
    Abstract: A bumper absorber for protecting pedestrians (20) is formed into a W-shaped cross-sectional configuration, as taken along a direction which is orthogonal to a longitudinal direction of the bumper absorber. The W-shaped cross sectional configuration has portions in which a front notch portion (22), an upper rear notch portion (24), and a lower rear notch portion (26) overlap with one another in a vertical direction of a vehicle. Ribs (30) are formed respectively at the upper rear notch portion (24) and the lower rear notch portion (26), and a triangular notch (32) is formed from a vehicle rear side at each of the rib (30). Further, the ribs 30 are formed at the upper rear notch portion (24) and the lower rear notch portion (26) so as to be separated from each other at predetermined intervals in a longitudinal direction of the bumper absorber, namely, in a transverse direction of the vehicle. With this structure, a rise in impact load acting on a pedestrian who is hit by a bumper can be controlled.
    Type: Grant
    Filed: September 30, 2003
    Date of Patent: June 5, 2007
    Assignees: Sekisui Kaseihin Kogyo Kabushiki Kaisha, Kabushiki Kaisha Chugai
    Inventors: Junji Adachi, Naruaki Abe, Fumihiko Sato, Taku Fukuyama, Kouji Mori, Yoshikatsu Miwa, Yukiya Morita
  • Publication number: 20060131899
    Abstract: A bumper absorber for protecting pedestrians (20) is formed into a W-shaped cross-sectional configuration, as taken along a direction which is orthogonal to a longitudinal direction of the bumper absorber. The W-shaped cross sectional configuration has portions in which a front notch portion (22), an upper rear notch portion (24), and a lower rear notch portion (26) overlap with one another in a vertical direction of a vehicle. Ribs (30) are formed respectively at the upper rear notch portion (24) and the lower rear notch portion (26), and a triangular notch (32) is formed from a vehicle rear side at each of the rib (30). Further, the ribs 30 are formed at the upper rear notch portion (24) and the lower rear notch portion (26) so as to be separated from each other at predetermined intervals in a longitudinal direction of the bumper absorber, namely, in a transverse direction of the vehicle. With this structure, a rise in impact load acting on a pedestrian who is hit by a bumper can be controlled.
    Type: Application
    Filed: September 30, 2003
    Publication date: June 22, 2006
    Inventors: Junji Adachi, Naruaki Abe, Fumihiko Sato, Taku Fukuyama, Kouji Mori, Yoshikatsu Miwa, Yukiya Morita
  • Patent number: 5942224
    Abstract: A method using a therapeutic agent for cat respiratory diseases which contains a human interferon as an effective ingredient. The therapeutic agent exerts a strong efficacy on cats with only a small dose even if administered to them orally or parenterally, and reduces the labor and burden of veterinaries and cat owners by a large margin.
    Type: Grant
    Filed: December 22, 1995
    Date of Patent: August 24, 1999
    Assignee: Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo
    Inventors: Yoshikatsu Miwa, Takatoshi Tamura, Hitoshi Murasaki, Masakazu Mitsuhashi
  • Patent number: 5714476
    Abstract: Neotrehalose is prepared in a relatively high-yield by a process comprising allowing .beta.-galactosidase to act on a solution containing lactoneotrehalose to form neotrehalose and recoverying the resultant neotrehalose. The neotrehalose is a non-reducing oligosaccharide having a satisfiable stability and a rich- and high-quality-sweetness and is assimilated and utilized as energy source in vivo when orally administered. Neotrehalose in the form of crystal has a satisfiable handleability because it is readily soluble in water and substantially free of hygroscopicity. These render neotrehalose very useful in the fields of food-, cosmetic- and pharmaceutical-industries.
    Type: Grant
    Filed: September 30, 1994
    Date of Patent: February 3, 1998
    Assignee: Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo
    Inventors: Yoshikatsu Miwa, Takashi Shibuya, Hiroto Chaen
  • Patent number: 5403727
    Abstract: Neotrehalose is prepared in a relatively high-yield by a process comprising allowing .beta.-galactosidase to act on a solution containing lactoneotrehalose to form neotrehalose and recovering the resultant neotrehalose. The neotrehalose is a non-reducing oligosaccharide having a satisfiable stability and a rich- and high-quality-sweetness and is assimilated and utilized as energy source in vivo when orally administered. Neotrehalose in the form of crystal has a satisfiable handleability because it is readily soluble in water and substantially free of hygroscopicity. These render neotrehalose very useful in the fields of food-, cosmetic- and pharmaceutical-industries.
    Type: Grant
    Filed: May 2, 1994
    Date of Patent: April 4, 1995
    Assignee: Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo
    Inventors: Yoshikatsu Miwa, Takashi Shibuya, Hiroto Chaen