Abstract: In one embodiment, the present invention provides an antibody specifically binding to human GH or an antigen-binding fragment thereof. In one embodiment, the present invention relates to an antibody specifically binding to human GH or an antigen-binding fragment thereof, comprising a heavy chain variable region (VH) and a light chain variable region (VL), wherein the VH comprises an amino acid sequence set forth in SEQ ID NO: 5 as a VH complementarity-determining region (CDR) 1 (VHCDR1), an amino acid sequence set forth in SEQ ID NO: 6 as a VHCDR2, and an amino acid sequence set forth in SEQ ID NO: 7 as a VHCDR3, and the VL comprises an amino acid sequence set forth in SEQ ID NO: 8 as a VL complementarity-determining region (CDR) 1 (VLCDR1), an amino acid sequence set forth in SEQ ID NO: 9 as a VLCDR2, and an amino acid sequence set forth in SEQ ID NO: 10 as a VLCDR3.

Abstract: A tilt and trim adjustment mechanism includes an improved arrangement of a powering unit in order to reduce the size of the assembly, including the size of the hydraulic motor used to raise and lower the outboard motor. The powering unit is mounted on a lower end of the hydraulic motor so that the brackets of an associated coupling assembly (i.e., swivel and clamping brackets) do not have to be widened in order to accommodate the tilt and trim adjustment mechanism. In addition, the hydraulic motor can be arranged to position the motor at the center of the assembly. By having the hydraulic motor act at the center of gravity of the assembly, a smaller hydraulic motor can be used. In addition, the tilt and trim adjustment system includes an improved manual override valve that includes a push button actuator. No tools are required to open the valve. In addition, the button is conveniently located on the powering assembly to be accessible for manually lowering the outboard motor.

Abstract: An improved flow control mechanism for a tilt and trim adjustment systern quickens tilt operation of an associated outboard drive, without sacrificing a desired control when trimming the outboard drive. The flow control mechanism includes a bypass line that interconnects the two sides of a respective tilt and trim cylinder. A bypass valve regulates flow through the bypass line. The bypass valve opens the bypass line when moving the outboard drive within the tilt range to quicken this operation. When moving the outboard drive within the trim range, however, the bypass valve closes the bypass line and connects an up chamber of the cylinder to a suction side of the pump to slow the speed at which the tilt and trim adjustment systern moves the outboard drive within this range of movement. The slower speed by which the systern raises and lowers the outboard drive enhances the ability to control the adjustment of the outboard drive's trim position.

Abstract: An improved flow control mechanism for a tilt and trim adjustment system quickens tilt and trim operations of an associated outboard drive. The flow control mechanism includes a bypass line that interconnects the two sides of a respective tilt and trim cylinder. A bypass valve regulates flow through the bypass line. The bypass valve opens the bypass line when raising the outboard drive to quicken this operation. When lowering the outboard drive, however, the bypass valve closes the bypass line and connects an up chamber of the cylinder to a suction side of the pump to slow the speed at which the tilt and trim adjustment system lowers the outboard drive. The flow control mechanism also inhibits the flow of working fluid through the system when the pump is inactive.