Patents by Inventor Yoshikazu Takada

Yoshikazu Takada has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6013495
    Abstract: The present invention provides a method for inhibiting cell proliferation in a cell comprising contacting the cell with a nucleic acid sequence or a polypeptide having essentially the sequence of the .beta..sub.1C integrin. Also included in the invention are peptides consisting of amino acid residues which are the size of or fewer than the sequence of the cytoplasmic domain of the .beta..sub.1C integrin consisting essentially of the amino acid sequence of SEQ ID NO:1 and SEQ ID NO:2, and functional fragments thereof which are useful for inhibiting cellular proliferation. Peptides, polynucleotides, and antibodies immunoreactive with the peptides, and methods of use for inhibiting cell growth are also provided.
    Type: Grant
    Filed: October 14, 1997
    Date of Patent: January 11, 2000
    Assignee: The Scripps Research Institute
    Inventors: Martin A. Schwartz, Jere E. Meredith, Jr., Yoshikazu Takada, Lucia Languino
  • Patent number: 5993568
    Abstract: A soft magnetic alloy sheet has low residual magnetic flux density. The alloy sheet comprises a base element and an alloying element having a concentration gradient in a thickness direction of the alloy sheet. The alloying element is selected from Si, Al, Ni, Co and Fe.
    Type: Grant
    Filed: March 25, 1998
    Date of Patent: November 30, 1999
    Assignee: NKK Corporation
    Inventors: Yoshikazu Takada, Hironori Ninomiya, Misao Namikawa, Koichiro Fujita, Shoji Kasai, Tatsuhiko Hiratani
  • Patent number: 5583203
    Abstract: Three new and distinct heterodimers in the very late antigen (VLA) protein family are disclosed, namely VLA-3, VLA-4 and VLA-5, as well as monoclonal antibodies therefor. The N-terminal amino acid sequence for each of the VLA .alpha. subunits is also disclosed.
    Type: Grant
    Filed: March 7, 1995
    Date of Patent: December 10, 1996
    Assignee: Dana-Farber Cancer Institute
    Inventors: Martin E. Hemler, Yoshikazu Takada
  • Patent number: 5089061
    Abstract: The present invention relates to a method for producing high silicon steel strip in a continuous treatment line through chemical vapor deposition (called "CVD" hereinafter), wherein the steel strip is subjected continuously to siliconization at temperatures between 1023.degree. and 1200.degree. C. by CVD in a non-oxidizing gas atmosphere containing SiCl.sub.4 between 5% and 35% in molar fraction. Subsequently a diffusion treatment is performed in a non-oxidizing gas atmosphere not containing SICl.sub.4 for diffusing Si uniformly throughout the steel strip, which is then cooled and coiled. If required, the steel strip may be coated with an insolating film and subjected to a baking treatment, before cooling and coiling.
    Type: Grant
    Filed: September 22, 1988
    Date of Patent: February 18, 1992
    Assignee: NKK Corporation
    Inventors: Masahiro Abe, Kazuhisa Okada, Shuzo Fukuda, Yasushi Tanaka, Masayuki Yamato, Yoshikazu Takada
  • Patent number: 4986341
    Abstract: The present invention relates to a process for making non-oriented high Si steel sheet without problems during the sequence from the step of making molten steel to the step of rolling to final sheet thickness. An ingot (or a continuously cast piece) of high Si steel (containing 4.0 to 7.0% Si and specified with Al, Mn, C and P) is subjected to slabbing-hot rolling (or else directly slab rolling-hot rolling) and subsequently the hot rolled steel is reduced to thin thickness. The steel material is maintained at temperature of more than a determined temperature from the step of making molten steel to the step of hot rolling. In the step of hot rolling, information regarding finish rolling conditions and coiling conditions is used to provide structure suitable for the subsequent thin rolling. The hot rolled steel is then warm-rolled to the required thickness.
    Type: Grant
    Filed: December 15, 1988
    Date of Patent: January 22, 1991
    Assignee: Nippon Kokan Kabushiki Kaisha
    Inventors: Sadakazu Masuda, Fumio Fujita, Masamoto Kamata, Masahiko Yoshini, Takashi Ariizumi, Yuji Okami, Yoshikazu Takada, Junichi Inagaki
  • Patent number: 4832762
    Abstract: An ordinarily made thin steel sheet is placed in an atmosphere bearing SiCl.sub.4, and subjecting to Si penetrating treatment at temperatures between 1100.degree. C. and 1200.degree. C. for a determined period of time. A heating rate is used which is more than 50.degree. C./sec at the temperatures of more than 1000.degree. C. in the SiCl.sub.4 atmosphere.Thereby, it is possible to manufacture thin steel sheet of high magnetic permeability without internal defects.
    Type: Grant
    Filed: March 3, 1986
    Date of Patent: May 23, 1989
    Assignee: Nippon Kokan Kabushiki Kaisha
    Inventors: Kazuhide Nakaoka, Yoshikazu Takada, Yasushi Tanaka
  • Patent number: 4773948
    Abstract: Fe alloy containing Si: 4.0 to 7.0 wt %, Mn: not more than 0.5 wt %, P: not more than 0.1 wt %, S: not more than 0.02 wt %, Al: not more than 2 wt % is molten, and made an ingot or continuously cast into a piece. The piece is subjected to slabbing-roughing, otherwise roughing at temperature of more than 1000.degree. C. and at total reduction of more than 50%, and further a hot finish rolling. The hot finish rolling is performed at temperature of not more than 1100.degree. C. and under a total reduction which is specified by a relation between average grain diameter before the hot finish rolling and Si content, and coiled at temperature of not more than 750.degree. C. after the rolling. The hot rolled plate is performed with cold rolling or warm rolling after the descaling and hot rolled strip annealing. If required, an intermediate annealing is performed in the course of the cold (or warm) rolling.
    Type: Grant
    Filed: January 30, 1987
    Date of Patent: September 27, 1988
    Assignee: Nippon Kokan Kabushiki Kaisha
    Inventors: Kazuhide Nakaoka, Yoshikazu Takada, Junichi Inagaki, Akira Hiura
  • Patent number: 4715905
    Abstract: Fe alloy containing Si more than 4.0 wt % is produced by a thin plate casting process. The producing condition depends upon rapid solidification of Fe alloy from a molten condition at cooling rate of more than 1.degree. C./sen to less than 10.sup.5 .degree. C./sec.The obtained thin cast plates are subjected to a hot rolling of more than 30% at the temperature range of 600.degree. to 800.degree. C., and to the cold rolling to a determined thickness, followed pickling. By the above mentioned conditions, operations of the industrial scale may be practiced without cracks on the surface in the cold rolling excellent magnetic characteristics may be provided by passing the annealing after the cold rolling.
    Type: Grant
    Filed: February 10, 1986
    Date of Patent: December 29, 1987
    Assignee: Nippon Kokan Kabushiki Kaisha
    Inventors: Kazuhide Nakaoka, Yoshikazu Takada, Junichi Inagaki, Akira Hiura
  • Patent number: 4052235
    Abstract: In a continuous annealing operation of a cold rolled steel strip involving water quenching and over-aging treatments, a method employing a cooling system comprising a pair of rolls arranged to contact the surfaces of a steel strip, a pair of cooling water spray units arranged in symmetrical positions on both sides of the steel strip and a storage tank connected to the spray units. When the steel strip, heated to a temperature between 500.degree. to 800.degree. C is water quenched, the distortion of the strip during the water quenching is inhibited and the surface oxidation is reduced to such an extent that no supplementary pickling is required.
    Type: Grant
    Filed: September 29, 1975
    Date of Patent: October 4, 1977
    Assignee: Nippon Kokan Kabushiki Kaisha
    Inventors: Kazuhide Nakaoka, Kenji Araki, Yoshikazu Takada, Shinobu Osaka, Katsuhiko Hirogami