Patents by Inventor Yoshiki Akatsuka

Yoshiki Akatsuka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cytotoxic T-cell epitope peptides that specifically attack epstein-barr virus-infected cells and uses thereof
    Patent number: 8481051
    Abstract: The present inventors introduced mRNAs for the Epstein-Barr virus proteins LMP1 and EBNA1 into antigen-presenting cells, and as a result, demonstrated that the cells induced Epstein-Barr virus-specific cytotoxic T cells. The present inventors also demonstrated that the cytotoxic T cells recognized epitope peptides presented via HLA-A*0206, HLA-Cw*0303, or HLA-Cw*0304, inhibited the outgrowth of Epstein-Barr virus-infected B cells, and lysed Epstein-Barr virus-infected NK lymphomas and NK cells.
    Type: Grant
    Filed: October 27, 2006
    Date of Patent: July 9, 2013
    Assignee: Medical and Biological Laboratories Co., Ltd.
    Inventors: Kiyotaka Kuzushima, Yoshinori Ito, Ayako Okamura, Yoshiki Akatsuka, Yasuo Morishima
  • CYTOTOXIC T-CELL EPITOPE PEPTIDES THAT SPECIFICALLY ATTACK EPSTEIN-BARR VIRUS-INFECTED CELLS AND USES THEREOF
    Publication number: 20090305324
    Abstract: The present inventors introduced mRNAs for the Epstein-Barr virus proteins LMP1 and EBNA1 into antigen-presenting cells, and as a result, demonstrated that the cells induced Epstein-Barr virus-specific cytotoxic T cells. The present inventors also demonstrated that the cytotoxic T cells recognized epitope peptides presented via HLA-A*0206, HLA-Cw*0303, or HLA-Cw*0304, inhibited the outgrowth of Epstein-Barr virus-infected B cells, and lysed Epstein-Barr virus-infected NK lymphomas and NK cells.
    Type: Application
    Filed: October 27, 2006
    Publication date: December 10, 2009
    Applicants: MEDICAL AND BIOLOGICAL LABORATORIES CO., LTD, AICHI PREFECTURE
    Inventors: Kiyotaka Kuzushima, Yoshinori Ito, Ayako Okamura, Yoshiki Akatsuka, Yasuo Morishima