Abstract: The object of the present invention is to provide a method for treating diabetes which is simple, safe and effective when compared to conventional diabetes treatment. The administration of one or more stem cell-recruiting factors allows a simple and safe repair of disrupted ?-cells in pancreatic Langerhans' islets. Thus, the therapeutic agent of the present invention which comprises one or more stem cell-recruiting factors as active ingredients is useful for diabetes treatment. Examples of such a stem cell-recruiting factor include colony-stimulating factors such as G-CSF.

Abstract: A method for producing a multi layered coating film by applying an intermediate coating composition on an article to form an intermediate coating thereon; applying a metallic color base coating composition on the intermediate coating to form a metallic color base coating thereon; and applying a clear coating composition on the metallic color base coating to form a clear coating thereon. The metallic color base coating composition is waterborne and contains an acryl emulsion resin; a water dispersion of a hydrophobic melamine resin having an average particle size within a range of from 20 to 300 nm; a luster color pigment; and an organic alcohol solvent having a solubility in water within a range of from 0.01 to 5.0 wt % and a boiling point within a range of from 160 to 200° C.

Abstract: The object of the present invention is to provide a method for treating diabetes which is simple, safe and effective when compared to conventional diabetes treatment. The administration of one or more stem cell-recruiting factors allows a simple and safe repair of disrupted ?-cells in pancreatic Langerhans' islets. Thus, the therapeutic agent of the present invention which comprises one or more stem cell-recruiting factors as active ingredients is useful for diabetes treatment. Examples of such a stem cell-recruiting factor include colony-stimulating factors such as G-CSF.

Abstract: A pharmaceutical composition, and a method using the composition, for prevention and/or treatment of fatty liver or hepatic disease, the composition comprising, as an active ingredient, a compound of the formula (1): where R1 is a hydrogen atom, an acyl group, or an arylalkoxycarbonyl group; and R2 and R3 are each independently a substituted or unsubstituted alkyl group, a substituted or unsubstituted alkenyl group, or a substituted or unsubstituted alkynyl group, or R2 and R3 may combine to form a cycloalkyl group.

Abstract: An object of the present invention is to provide a pharmaceutical composition and a method for preventing or treating a respiratory disease. The pharmaceutical composition comprises a compound represented by formula (1): or a pharmaceutically acceptable salt thereof as an active ingredient.

Abstract: Herein provided is a novel pharmaceutical composition for ameliorating the vascular tone-regulating function of vascular endothelium, comprising a compound represented by formula (1): wherein R1 represents a hydrogen atom or an acyl or arylalkyloxycarbonyl group; R2 and R3 are identical or different and represent an optionally substituted alkyl group, an optionally substituted alkenyl group or an optionally substituted alkynyl group; or R2 and R3 may together form a cycloalkyl group.

Abstract: A pharmaceutical composition comprising a compound represented by the following formula: 1

Abstract: This invention provides a screening method for sterol regulatory element binding protein (SREBP) pathway-specific inhibitors using a mutant cultured cell, as well as therapeutic agents for hyperlipemia, arterial sclerosis, obesity or cancer containing an SREBP pathway-specific inhibitor selected by said screening method.

Abstract: This invention provides a screening method for sterol regulatory element binding protein (SREBP) pathway-specific inhibitors using a mutant cultured cell, as well as therapeutic agents for hyperlipemia, arterial sclerosis, obesity or cancer containing an SREBP pathway-specific inhibitor selected by said screening method.