Patents by Inventor Yoshiki Sekijima

Yoshiki Sekijima has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for treating transthyretin amyloid diseases
    Patent number: 7560488
    Abstract: Kinetic stabilization of the native state of transthyretin is an effective mechanism for preventing protein misfolding. Because transthyretin misfolding plays an important role in transthyretin amyloid diseases, inhibiting such misfolding can be used as an effective treatment or prophylaxis for such diseases. Treatment methods are disclosed.
    Type: Grant
    Filed: September 25, 2006
    Date of Patent: July 14, 2009
    Assignee: The Scripps Research Institute
    Inventors: Jeffery W. Kelly, Yoshiki Sekijima
  • Compositions and methods for stabilizing transthyretin and inhibiting transthyretin misfolding
    Patent number: 7214696
    Abstract: Kinetic stabilization of the native state of transthyretin is an effective mechanism for preventing protein misfolding. Because transthyretin misfolding plays an important role in transthyretin amyloid diseases, inhibiting such misfolding can be used as an effective treatment or prophylaxis for such diseases. Treatment methods, screening methods, as well as specific transthyretin stabilizing compounds are disclosed.
    Type: Grant
    Filed: October 21, 2005
    Date of Patent: May 8, 2007
    Assignee: The Scripps Research Institute
    Inventors: Jeffery W. Kelly, Yoshiki Sekijima
  • Methods for treating transthyretin amyloid diseases
    Publication number: 20070078186
    Abstract: Kinetic stabilization of the native state of transthyretin is an effective mechanism for preventing protein misfolding. Because transthyretin misfolding plays an important role in transthyretin amyloid diseases, inhibiting such misfolding can be used as an effective treatment or prophylaxis for such diseases. Treatment methods are disclosed.
    Type: Application
    Filed: September 25, 2006
    Publication date: April 5, 2007
    Inventors: Jeffery Kelly, Yoshiki Sekijima
  • Compositions and methods for stabilizing transthyretin and inhibiting transthyretin misfolding
    Publication number: 20060057644
    Abstract: Kinetic stabilization of the native state of transthyretin is an effective mechanism for preventing protein misfolding. Because transthyretin misfolding plays an important role in transthyretin amyloid diseases, inhibiting such misfolding can be used as an effective treatment or prophylaxis for such diseases. Treatment methods, screening methods, as well as specific transthyretin stabilizing compounds are disclosed.
    Type: Application
    Filed: October 21, 2005
    Publication date: March 16, 2006
    Inventors: Jeffery Kelly, Yoshiki Sekijima
  • Compositions and methods for stabilizing transthyretin and inhibiting transthyretin misfolding
    Publication number: 20040152140
    Abstract: Kinetic stabilization of the native state of transthyretin is an effective mechanism for preventing protein misfolding. Because transthyretin misfolding plays an important role in transthyretin amyloid diseases, inhibiting such misfolding can be used as an effective treatment or prophylaxis for such diseases. Treatment methods, screening methods, as well as specific transthyretin stabilizing compounds are disclosed.
    Type: Application
    Filed: December 19, 2003
    Publication date: August 5, 2004
    Inventors: Jeffery W. Kelly, Yoshiki Sekijima