Patents by Inventor Yoshiki Tokura

Yoshiki Tokura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTIBODY SPECIFIC TO PROFILAGGRIN C-TERMINAL DOMAIN, AND USE THEREOF
    Publication number: 20190079080
    Abstract: The present invention provides an antibody specific to a C-terminal domain of a human profilaggrin gene, wherein the C-terminal domain is a peptide comprising the amino acid sequence set forth in SEQ ID NO:1 or a variant thereof, a method for detecting a filaggrin gene mutation using the antibody, and a kit for the detection.
    Type: Application
    Filed: September 20, 2018
    Publication date: March 14, 2019
    Applicant: Shiseido Company, Ltd.
    Inventors: Toshihiko HIBINO, Mami YAMAMOTO, Masaya TAKAGI, Junichi SAKABE, Yoshiki TOKURA
  • ANTIBODY SPECIFIC TO PROFILAGGRIN C-TERMINAL DOMAIN, AND USE THEREOF
    Publication number: 20140287431
    Abstract: The present invention provides an antibody specific to a C-terminal domain of a human profilaggrin gene, wherein the C-terminal domain is a peptide comprising the amino acid sequence set forth in SEQ ID NO:1 or a variant thereof, a method for detecting a filaggrin gene mutation using the antibody, and a kit for the detection.
    Type: Application
    Filed: November 8, 2012
    Publication date: September 25, 2014
    Inventors: Toshihiko Hibino, Mami Yamamoto, Masaya Takagi, Junichi Sakabe, Yoshiki Tokura
  • Itch suppressant
    Patent number: 8445439
    Abstract: The present invention provides an itch suppressant containing cholecystokinin 2 receptor agonist such as a peptide having an amino acid sequence homologous with a partial amino acid sequence of at least seven C-terminal amino acids of the peptide having the amino acid sequence represented by SEQ:ID No. 1 as an active ingredient as a rapid-acting itch suppressant effective in treating skin illnesses associated with strong itch such as atopic dermatitis having few side effects. [SEQ:?ID?No.
    Type: Grant
    Filed: October 22, 2010
    Date of Patent: May 21, 2013
    Assignee: University of Occupational and Environmental Health, Japan
    Inventors: Yoshiki Tokura, Shoko Fukamachi
  • ITCH SUPPRESSANT
    Publication number: 20120214743
    Abstract: The present invention provides an itch suppressant containing cholecystokinin 2 receptor agonist such as a peptide having an amino acid sequence homologous with a partial amino acid sequence of at least seven C-terminal amino acids of the peptide having the amino acid sequence represented by SEQ:ID No. 1 as an active ingredient as a rapid-acting itch suppressant effective in treating skin illnesses associated with strong itch such as atopic dermatitis having few side effects. [SEQ:?ID?No.
    Type: Application
    Filed: October 22, 2010
    Publication date: August 23, 2012
    Applicant: University of Occupational and Environmental Health, Japan
    Inventors: Yoshiki Tokura, Shoko Fukamachi
  • Remedy for prurigo
    Patent number: 5972365
    Abstract: As a remedy for prurigo, IFN-.gamma. is administered systemically, preferably intravenously and still preferably via drip infusion, in a daily dose of from 250,000 JRU to 4,000,000 JRU preferably once a day or in several portions depending on the conditions of the patient and side effects. The administration method and dose can be changed depending on the conditions, age, etc., of the patient.IFN-.gamma. is highly effective in the treatment of prurigo. The action of IFN-.gamma. to normalize the imbalance in peripheral lymphocytes is suggested as the mechanism for the efficacy of IFN-.gamma. in the treatment of prurigo.
    Type: Grant
    Filed: September 6, 1996
    Date of Patent: October 26, 1999
    Assignee: Suntory Limited
    Inventors: Masahiro Takigawa, Yoshiki Tokura