Abstract: The present inventors have found that HMGB1 fragment peptides having a particular amino acid sequence exhibit the effects of improvement of cardiac function, inhibition of cardiomyocyte hypertrophy, inhibition of myocardial fibrosis, and promotion of angiogenesis in an animal model of dilated cardiomyopathy, that the particular HMGB1 fragment peptides also exhibit the effects of improvement of cardiac function, inhibition of cardiomegaly, inhibition of cardiomyocyte hypertrophy, inhibition of myocardial fibrosis, and promotion of angiogenesis in an animal model of ischemic cardiomyopathy caused by old myocardial infarction, and that the particular HMGB1 fragment peptides exhibit the effects of inhibition of cardiomyocyte hypertrophy and inhibition of myocardial fibrosis in an animal model of hypertensive cardiomyopathy.

Abstract: Provided is a liquid tank, including: a cylindrical seamless tank body having both end portions being reduced in diameter toward respective end sides; and a plurality of annular baffles provided inside the tank body and arranged at intervals in an axial direction of the tank body, in which at least one of the plurality of baffles is held on an inner peripheral surface of the tank body.

Abstract: A negative thermal expansion material, being formed from MxSryBazZn2Si2O7 (wherein M is one or more types of Na and Ca, and x+y+z=1, 0<x?0.5, 0.3<z<1.0), and an XRD peak intensity INTR and a background intensity IBG of a primary phase of an orthorhombic crystal structure which exhibits negative expansion characteristics satisfy a relation of INTE/IBG>15. An object of the present invention is to provide a negative thermal expansion material having a low specific gravity, and a negative thermal expansion material having a low Ba content.

Abstract: A YAG ceramic bonded body in which a YAG ceramic and a YAG ceramic or optical glass are bonded, wherein the YAG ceramic bonded body comprises glass as a bonding layer, and has a rate of change of transmittance that is within 7%. An object of this invention is to provide a bonded body in which a YAG ceramic and a YAG ceramic are bonded, or a bonded body in which a YAG ceramic and optical glass are bonded, and which is capable of suppressing the reflection of light at the bonded interface, as well as the production method thereof.

Abstract: A polycrystalline YAG sintered body, wherein, when dimensions of a smallest rectangular solid surrounding a YAG sintered body are A mm×B mm×C mm, a maximum value (A, B, C) is 150 mm or less, a minimum value (A, B, C) is more than 20 mm and 40 mm or less, and an optical loss coefficient when light of a wavelength of 300 to 1500 nm (excluding wavelengths which result in absorption of light by an additive element) is transmitted therethrough is 0.002 cm?1 or less. Moreover, a polycrystalline YAG sintered body, wherein, when dimensions of a smallest rectangular solid surrounding a YAG sintered body are A mm×B mm×C mm, a maximum value (A, B, C) is more than 150 mm and 300 mm or less, a minimum value (A, B, C) is more than 5 mm and 40 mm or less, and an optical loss coefficient when light of a wavelength of 300 to 1500 nm (excluding wavelengths which result in absorption of light by an additive element) is transmitted therethrough is 0.002 cm?1 or less.

Abstract: A Cr:YAG sintered body including Al, Y, Cr, Ca, Mg, Si, and O, and component contents in the sintered body satisfying conditional expressions of 1) to 3) below, provided in the Conditional expression, each chemical symbol represents a component content (atppm). |(Y+Ca)/(Al+Cr+Si+Mg)?0.6|<0.001;??1) 0?(Ca+Mg)?(Cr+Si)?50 atppm; and??2) 50?Si?500 atppm??3) The embodiment of the present invention is to provide a Cr:YAG sintered body which exhibits high transparency and has a high Cr4+ conversion ratio, and its production method.

Abstract: A light absorbing layer which is bonded to a laser medium to configure a bonded body, wherein the light absorbing layer is formed from a glass material and, in an oscillation wavelength (wavelength of 650 nm or more and less than 1400 nm) of the laser medium, an absorption coefficient is 0.1 to 10.0 cm-1, a difference in refractive index between the light absorbing layer and the laser medium is within ±0.1, and a difference in linear thermal expansion coefficient between the light absorbing layer and the laser medium is within ±1 ppm/K. The present invention relates to a light absorbing layer for preventing parasitic oscillation, and aims to provide a material capable of suppressing the manufacturing cost and which can be easily processed for preparing a bonded body.

Abstract: A Cr:YAG sintered body including Al, Y, Cr, Ca, Mg, Si, and O, and component contents in the sintered body satisfying conditional expressions of 1) to 3) below, provided in the Conditional expression, each chemical symbol represents a component content (atppm). |(Y+Ca)/(Al+Cr+Si+Mg)?0.6|<0.001;??1) 0?(Ca+Mg)?(Cr+Si)?50 atppm; and??2) 50?Si?500 atppm??3) The embodiment of the present invention is to provide a Cr:YAG sintered body which exhibits high transparency and has a high Cr4+ conversion ratio, and its production method.

Abstract: A polycrystalline YAG sintered body, wherein, when dimensions of a smallest rectangular solid surrounding a YAG sintered body are A mm×B mm×C mm, a maximum value (A, B, C) is 150 mm or less, a minimum value (A, B, C) is more than 20 mm and 40 mm or less, and an optical loss coefficient when light of a wavelength of 300 to 1500 nm (excluding wavelengths which result in absorption of light by an additive element) is transmitted therethrough is 0.002 cm?1 or less. Moreover, a polycrystalline YAG sintered body, wherein, when dimensions of a smallest rectangular solid surrounding a YAG sintered body are A mm×B mm×C mm, a maximum value (A, B, C) is more than 150 mm and 300 mm or less, a minimum value (A, B, C) is more than 5 mm and 40 mm or less, and an optical loss coefficient when light of a wavelength of 300 to 1500 nm (excluding wavelengths which result in absorption of light by an additive element) is transmitted therethrough is 0.002 cm?1 or less.

Abstract: A negative thermal expansion material, being formed from MxSryBazZn2Si2O7 (wherein M is one or more types of Na and Ca, and x+y+z=1, 0<x?0.5, 0.3<z<1.0), and an XRD peak intensity INTR and a background intensity IBG of a primary phase of an orthorhombic crystal structure which exhibits negative expansion characteristics satisfy a relation of INTE/IBG>15. An object of the present invention is to provide a negative thermal expansion material having a low specific gravity, and a negative thermal expansion material having a low Ba content.

Abstract: A moisture- or protein-adsorbability imparting agent, comprising a porous silica having a hexagonal pore structure, an average pore size of from 0.8 to 20 nm, an average particle size of 50 nm to 100 ?m, a specific surface area of from 400 to 2000 m2/g, and a pore volume of from 0.1 to 3.0 cm3/g; a material having an adsorbability of moisture or a protein, comprising the moisture- or protein-adsorbability imparting agent; and use of the moisture- or protein-adsorbability imparting agent for imparting absorbability of moisture or a protein to a material selected from the group consisting of food wrapping materials; filtration aid agents; sanitary articles; compositions containing a synthetic resin; moisture-controlled material; covering materials for wounds; insulation substrates; coating materials for semiconductor devices; cosmetics; inkjet recording media; and compositions containing synthetic fibers.

Abstract: A moisture- or protein-adsorbability imparting agent, comprising a porous silica having a hexagonal pore structure, an average pore size of from 0.8 to 20 nm, an average particle size of 50 nm to 100 ?m, a specific surface area of from 400 to 2000 m2/g, and a pore volume of from 0.1 to 3.0 cm3/g; a material having an adsorbability of moisture or a protein, comprising the moisture- or protein-adsorbability imparting agent; and use of the moisture- or protein-adsorbability imparting agent for imparting absorbability of moisture or a protein to a material selected from the group consisting of food wrapping materials; filtration aid agents; sanitary articles; compositions containing a synthetic resin; moisture-controlled material; covering materials for wounds; insulation substrates; coating materials for semiconductor devices; cosmetics; inkjet recording media; and compositions containing synthetic fibers.

Abstract: The present invention relates to a substance-supporting porous silica, wherein a porous silica supports a substance selected from the group consisting of menthols, volatile substances, thermal substances, plant polyphenols and organic colorants.