Patents by Inventor Yoshikuni Mizuno

Yoshikuni Mizuno has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pael receptor, cells and animal expressing pael receptor and method of screning remedy for parkinson's disease
    Publication number: 20060051835
    Abstract: An object of the present invention is to provide a substrate of Parkin, a system for elucidating the cause of Parkinson's disease using the substrate and a method of screening for a remedy for Parkinson's disease. An animal cell having a DNA encoding a human Pael receptor or a DNA having a variant of the DNA incorporated therein; a non-human mammal having a DNA carrying the aforementioned DNA incorporated therein; a probe comprising the whole or a part of DNA encoding the human Pael receptor; and an antibody specifically recognizing Pael receptor.
    Type: Application
    Filed: June 28, 2002
    Publication date: March 9, 2006
    Inventors: Ryosuke Takahashi, Yuzuru Imai, Nobutaka Hattori, Yoshikuni Mizuno, Mariko Soda, Haruhisa Inoue
  • Parkin protein as ubiquitin ligase
    Publication number: 20050042607
    Abstract: The use of Parkin protein (Parkin) as ubiquitin ligase (E3), and a new method of diagnosing juvenile Parkinsonism based on the use thereof.
    Type: Application
    Filed: February 26, 2001
    Publication date: February 24, 2005
    Inventors: Yoshikuni Mizuno, Nobuyoshi Shimizu
  • Isolated DNA or gene responsible for Parkinson's disease
    Publication number: 20050003385
    Abstract: This invention provides an isolated DNA or gene that is responsible for Parkinson's disease and is useful in diagnosing and treating the disease etc. The isolated DNA or gene according to this invention comprises a full-length base sequence according to the sequence ID. No. 1 or 3, or a partial sequence thereof, or a base sequence hybridizable thereto or hybridizable with a complementary strand thereof, and being associated with Parkinson's disease.
    Type: Application
    Filed: February 12, 2004
    Publication date: January 6, 2005
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Nobuyoshi Shimizu, Yoshikuni Mizuno
  • Isolated DNA or gene responsible for Parkinson's disease
    Patent number: 6716621
    Abstract: This invention provides an isolated DNA or gene that is responsible for Parkinson's disease and is useful in diagnosing and treating the disease etc. The isolated DNA or gene according to this invention comprises a full-length base sequence according to the sequence ID. No. 1 or 2, or a partial sequence thereof, or a base sequence hybridizable thereto or hybridizable with a complemental strand thereof, and being associated with Parkinson's disease.
    Type: Grant
    Filed: August 9, 2000
    Date of Patent: April 6, 2004
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Nobuyoshi Shimizu, Yoshikuni Mizuno
  • Therapeutic drug for dementia
    Patent number: 4690949
    Abstract: A therapeutic drug for dementia is provided which comprises, as an active ingredient, DL- or L-threo-3,4-dihydroxyphenylserine of the formula ##STR1## or its salt.
    Type: Grant
    Filed: April 29, 1986
    Date of Patent: September 1, 1987
    Assignee: Sumitomo Pharmaceuticals Company, Limited
    Inventors: Mitsuo Yoshida, Yoshikuni Mizuno, Natsue Shimizu, Mieko Otsuka, Masakatsu Dobutsu, Yuusuke Furukawa, Yutaka Joshita