Patents by Inventor Yoshimasa Tanaka

Yoshimasa Tanaka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210204370
    Abstract: A heating coil is configured to induction heat a workpiece having a hole. The heating coil includes first and second heating units respectively having conductors. The conductors of the first and second heating units extend in inclination directions intersecting an axial direction and a circumferential direction of an outer peripheral surface of the workpiece.
    Type: Application
    Filed: May 21, 2019
    Publication date: July 1, 2021
    Applicant: NETUREN CO., LTD.
    Inventors: Maho HOSOGI, Yoshimasa TANAKA, Syoichiro IWASAKI, Hideyuki KOSAKI, Yuuji KODAMA
  • Publication number: 20210161963
    Abstract: The present invention provides a method for efficiently producing highly pure ??T cells introduced with foreign genes by culturing in the presence of IL-7 and IL-15 after stimulating the ??T cells with a bisphosphonic acid ester derivative. When a T cell receptor (TCR) or a chimeric antigen receptor (CAR) is introduced as a foreign gene, ??T cells in which TCR and CAR are functionally expressed can be obtained.
    Type: Application
    Filed: July 31, 2019
    Publication date: June 3, 2021
    Inventors: Hiroshi Shiku, Yoshihiro Miyahara, Satoshi Okumura, Takuma Kato, Tae Hayashi, Yoshimasa Tanaka
  • Publication number: 20210120637
    Abstract: An induction heating device is provided. The induction heating device comprises a plurality of induction heating devices disposed at intervals along the circumference of a ring-shaped workpiece, a setting unit for setting induction heating conditions, and a switching control unit. Each of the plurality of induction heating devices comprises heating coils disposed facing areas to be heated of the workpiece, a plurality of transformers connected to the heating coils in parallel, a plurality of matching units connected to any one of the plurality of transformers, an inverter unit having a rectifier unit and an inverter unit, an inverter control unit having a rectification control unit, and a group of switches.
    Type: Application
    Filed: December 28, 2020
    Publication date: April 22, 2021
    Applicant: NETUREN CO., LTD.
    Inventors: Hitoshi Nakatsu, Masato Yoshioka, Yoshimasa Tanaka, Tsutomu Ito, Kenji Koyanagi, Masaki Sagae, Tatsuya Ishii, Yoshitaka Misaka, Yasuharu Ogawa
  • Patent number: 10959297
    Abstract: A heating coil of a heat treatment apparatus is configured to inductively heat an elongated workpiece having a recessed lateral surface. The heating coil includes a base conductor and a projected conductor. A width of the projected conductor is narrower than a width of the base conductor. The projected conductor is arranged to project toward the recess from a position of the base conductor. The base conductor and the projected conductor are arranged to extend in a longitudinal direction of the workpiece. A heat treatment apparatus includes a cooling section and the heating coil. A heat treatment method uses the heating coil described above.
    Type: Grant
    Filed: February 27, 2013
    Date of Patent: March 23, 2021
    Assignee: NETUREN CO., LTD.
    Inventors: Yoshimasa Tanaka, Yutaka Sugiyama
  • Patent number: 10952288
    Abstract: An induction heating device and an induction heating method are provided. The entire areas to be heated of the workpiece can be uniformly heated to a predetermined high temperature, and uniform heating is possible even when the workpiece deforms in a non-uniform manner during heating. When areas to be heated are established on a workpiece so as to extend in one direction and the areas to be heated are induction-heated, the deformation amount on one edge of the areas to be heated is different from that on the other. This induction heating device includes; heating coils facing a portion of the areas to be heated when the workpiece is induction-heated; and a relative transfer means for transferring the workpiece and the heating coils along one direction in a relative manner, and the heating coils are disposed so as to correspond to the areas to be heated during the heating period.
    Type: Grant
    Filed: July 17, 2018
    Date of Patent: March 16, 2021
    Assignee: NETUREN CO., LTD.
    Inventors: Hitoshi Nakatsu, Masato Yoshioka, Yoshimasa Tanaka, Tsutomu Ito, Kenji Koyanagi, Masaki Sagae, Tatsuya Ishii, Yoshitaka Misaka, Yasuharu Ogawa
  • Patent number: 10912159
    Abstract: An induction heating device and an induction heating method are provided. The entire areas to be heated of the workpiece can be uniformly heated to a predetermined high temperature, and uniform heating is possible even when the workpiece deforms in a non-uniform manner during heating. When areas to be heated are established on a workpiece so as to extend in one direction and the areas to be heated are induction-heated, the deformation amount on one edge of the areas to be heated is different from that on the other. This induction heating device includes; heating coils facing a portion of the areas to be heated when the workpiece is induction-heated; and a relative transfer means for transferring the workpiece and the heating coils along one direction in a relative manner, and the heating coils are disposed so as to correspond to the areas to be heated during the heating period.
    Type: Grant
    Filed: July 17, 2018
    Date of Patent: February 2, 2021
    Assignee: NETUREN CO., LTD.
    Inventors: Hitoshi Nakatsu, Masato Yoshioka, Yoshimasa Tanaka, Tsutomu Ito, Kenji Koyanagi, Masaki Sagae, Tatsuya Ishii, Yoshitaka Misaka, Yasuharu Ogawa
  • Patent number: 10708984
    Abstract: In preferred embodiments, a heating coil is provided that includes at least a set of heating conductors, one of which is arranged at a side of a work and the other one is arranged at an opposite side of the work. In addition, a plurality of connecting conductors are provided to connect an end of one of the heating conductors with an end of the other heating conductor, wherein each of the heating conductors is connected with at least two connecting conductors. The connecting conductors extend from an end of each of the heating conductor in a different direction from each other. In the preferred embodiments, the heating coil has a simple structure that enables an even heat treatment to a work in a width direction.
    Type: Grant
    Filed: October 11, 2013
    Date of Patent: July 7, 2020
    Assignee: NETUREN CO., LTD.
    Inventors: Yoshimasa Tanaka, Yutaka Sugiyama
  • Patent number: 10648052
    Abstract: According to an embodiment, an induction heating coil includes a heating conductor portion which is formed of a conductor member and has a zigzag shape in which a bent portion opened to one side in a first direction and a bent portion opened to the other side in the first direction are alternately continuously arranged in opposite directions along a second direction crossing the first direction.
    Type: Grant
    Filed: November 17, 2016
    Date of Patent: May 12, 2020
    Assignee: Neturen Co., Ltd.
    Inventors: Yoshimasa Tanaka, Yoshitaka Misaka, Yuji Asano
  • Patent number: 10532065
    Abstract: The novel bisphosphonic acid ester derivatives represented by the following formula (1): Y—Cy—(NH)m—(CH2)n—C(X)(PO(OR1)(OR2))2??(1) wherein each symbol is as defined in the DESCRIPTION, which has an amino group substituted by a heterocyclic group or a heterocyclic group containing a nitrogen atom, and the acid moiety is esterified with a POM group, an n-butanoyloxymethyl (BuOM) group and the like, exhibit a superior direct or indirect cytotoxicity effect on tumor cells and virus infected cells.
    Type: Grant
    Filed: December 18, 2015
    Date of Patent: January 14, 2020
    Assignee: NAGASAKI UNIVERSITY
    Inventors: Yoshimasa Tanaka, Kenji Matsumoto, Kosuke Hayashi, Yuki Sakai, Nagahiro Minato
  • Publication number: 20190191496
    Abstract: A heating apparatus and a heating method are provided. The heating apparatus includes a coil configured to receive AC power to form a magnetic field that inductively heats a workpiece, a spray unit configured to spray cooling fluid including a liquid to the coil in a form of mist at least during a period in which the AC power is supplied to the coil. Alternatively, the spray unit may be configured to spray the cooling fluid in the form of mist to a heating target portion of the workpiece placed in the magnetic field at least during the period in which the AC power is supplied to the coil.
    Type: Application
    Filed: February 25, 2019
    Publication date: June 20, 2019
    Inventors: Hidehiro YASUTAKE, Yoshimasa TANAKA
  • Patent number: 10280188
    Abstract: A series of fluorine-containing bisphosphonic acids in which an alkylamine side chain is added, a series of fluorine-containing bisphosphonic acids in which an amino group substituted by a heterocyclic group or a heterocyclic group containing a nitrogen atom is added, to the carbon atom of P—C(F)—P, and a series of fluorine-containing bisphosphonate derivatives in which the acid moiety thereof is esterified by an alkoxymethyl group such as POM group, n-butanoyloxymethyl (BuOM) group and the like, that is, the fluorine-containing bisphosphonic acid and fluorine-containing bisphosphonate derivative represented by the following formula (I): wherein each symbol is as defined in the DESCRIPTION, can efficiently induce proliferation of peripheral blood ?? T cells that express V?2V?2 T cell receptor having superior cytotoxicity against tumor cells and virus infected cells, immunize tumor cells and virus infected cells, and can induce cytotoxicity by ?? T cells.
    Type: Grant
    Filed: February 1, 2016
    Date of Patent: May 7, 2019
    Assignee: Nagasaki University
    Inventors: Yoshimasa Tanaka, Satoshi Mizuta, Hiroshi Ueda
  • Patent number: 10175229
    Abstract: The present invention aims to provide a novel compound for measuring cellular cytotoxicity or cell proliferation capacity accurately with high reproducibility, conveniently and rapidly, and a measurement method of cellular cytotoxicity or cell proliferation capacity by using the compound. The present invention relates to a compound represented by the formula (I): wherein R1 is a substituent, R2 and R3 are each an optionally substituted hydrocarbon group, or an optionally substituted heterocyclic group, Y is a substituent, n is an integer of 0-3, Z is a single bond, —O—, —S—, —SO—, —SO2—, or —NR4— (R4 is a hydrogen atom or a substituent), and A is an optionally substituted C1-6 alkylene group) or a salt thereof.
    Type: Grant
    Filed: March 30, 2015
    Date of Patent: January 8, 2019
    Assignee: NAGASAKI UNIVERSITY
    Inventors: Yoshimasa Tanaka, Yuki Sakai, Satoshi Mizuta, Hiroshi Ueda
  • Publication number: 20180332672
    Abstract: An induction heating device and an induction heating method are provided. The entire areas to be heated of the workpiece can be uniformly heated to a predetermined high temperature, and uniform heating is possible even when the workpiece deforms in a non-uniform manner during heating. When areas to be heated are established on a workpiece so as to extend in one direction and the areas to be heated are induction-heated, the deformation amount on one edge of the areas to be heated is different from that on the other. This induction heating device includes; heating coils facing a portion of the areas to be heated when the workpiece is induction-heated; and a relative transfer means for transferring the workpiece and the heating coils along one direction in a relative manner, and the heating coils are disposed so as to correspond to the areas to be heated during the heating period.
    Type: Application
    Filed: July 17, 2018
    Publication date: November 15, 2018
    Applicant: NETUREN CO., LTD.
    Inventors: Hitoshi Nakatsu, Masato Yoshioka, Yoshimasa Tanaka, Tsutomu Ito, Kenji Koyanagi, Masaki Sagae, Tatsuya Ishii, Yoshitaka Misaka, Yasuharu Ogawa
  • Patent number: 10057945
    Abstract: An induction heating device and an induction heating method are provided. The entire areas to be heated of the workpiece can be uniformly heated to a predetermined high temperature, and uniform heating is possible even when the workpiece deforms in a non-uniform manner during heating. When areas to be heated are established on a workpiece so as to extend in one direction and the areas to be heated are induction-heated, the deformation amount on one edge of the areas to be heated is different from that on the other. This induction heating device includes: heating coils facing a portion of the areas to be heated when the workpiece is induction-heated; and a relative transfer means for transferring the workpiece and the heating coils along one direction in a relative manner, and the heating coils are disposed so as to correspond to the areas to be heated during the heating period.
    Type: Grant
    Filed: April 6, 2012
    Date of Patent: August 21, 2018
    Assignee: NETUREN CO., LTD.
    Inventors: Hitoshi Nakatsu, Masato Yoshioka, Yoshimasa Tanaka, Tsutomu Ito, Kenji Koyanagi, Masaki Sagae, Tatsuya Ishii, Yoshitaka Misaka, Yasuharu Ogawa
  • Publication number: 20180022769
    Abstract: A series of fluorine-containing bisphosphonic acids in which an alkylamine side chain is added, a series of fluorine-containing bisphosphonic acids in which an amino group substituted by a heterocyclic group or a heterocyclic group containing a nitrogen atom is added, to the carbon atom of P—C(F)—P, and a series of fluorine-containing bisphosphonate derivatives in which the acid moiety thereof is esterified by an alkoxymethyl group such as POM group, n-butanoyloxymethyl (BuOM) group and the like, that is, the fluorine-containing bisphosphonic acid and fluorine-containing bisphosphonate derivative represented by the following formula (I): wherein each symbol is as defined in the DESCRIPTION, can efficiently induce proliferation of peripheral blood ?? T cells that express V?2V?2 T cell receptor having superior cytotoxicity against tumor cells and virus infected cells, immunize tumor cells and virus infected cells, and can induce cytotoxicity by ?? T cells.
    Type: Application
    Filed: February 1, 2016
    Publication date: January 25, 2018
    Applicant: Nagasaki University
    Inventors: Yoshimasa TANAKA, Satoshi MIZUTA, Hiroshi UEDA
  • Publication number: 20170360811
    Abstract: The novel bisphosphonic acid ester derivatives represented by the following formula (1): Y—Cy—(NH)m—(CH2)n—C(X)(PO(OR1)(OR2))2 ??(1) wherein each symbol is as defined in the DESCRIPTION, which has an amino group substituted by a heterocyclic group or a heterocyclic group containing a nitrogen atom, and the acid moiety is esterified with a POM group, an n-butanoyloxymethyl (BuOM) group and the like, exhibit a superior direct or indirect cytotoxicity effect on tumor cells and virus infected cells.
    Type: Application
    Filed: December 18, 2015
    Publication date: December 21, 2017
    Applicant: NAGASAKI UNIVERSITY
    Inventors: Yoshimasa TANAKA, Kenji MATSUMOTO, Kosuke HAYASHI, Yuki SAKAI, Nagahiro MINATO
  • Publication number: 20170150553
    Abstract: A heating apparatus and a heating method are provided. The heating apparatus includes a coil configured to receive AC power to form a magnetic field that inductively heats a workpiece, a spray unit configured to spray cooling fluid including a liquid to the coil in a form of mist at least during a period in which the AC power is supplied to the coil. Alternatively, the spray unit may be configured to spray the cooling fluid in the form of mist to a heating target portion of the workpiece placed in the magnetic field at least during the period in which the AC power is supplied to the coil.
    Type: Application
    Filed: July 9, 2015
    Publication date: May 25, 2017
    Inventors: Hidehiro YASUTAKE, Yoshimasa TANAKA
  • Publication number: 20170067130
    Abstract: According to an embodiment, an induction heating coil includes a heating conductor portion which is formed of a conductor member and has a zigzag shape in which a bent portion opened to one side in a first direction and a bent portion opened to the other side in the first direction are alternately continuously arranged in opposite directions along a second direction crossing the first direction
    Type: Application
    Filed: November 17, 2016
    Publication date: March 9, 2017
    Applicant: Neturen Co., Ltd.
    Inventors: Yoshimasa Tanaka, Yoshitaka Misaka, Yuji Asano
  • Publication number: 20170016880
    Abstract: The present invention aims to provide a novel compound for measuring cellular cytotoxicity or cell proliferation capacity accurately with high reproducibility, conveniently and rapidly, and a measurement method of cellular cytotoxicity or cell proliferation capacity by using the compound. The present invention relates to a compound represented by the formula (I): wherein R1 is a substituent, R2 and R3 are each an optionally substituted hydrocarbon group, or an optionally substituted heterocyclic group, Y is a substituent, n is an integer of 0-3, Z is a single bond, —O—, —S—, —SO—, —SO2—, or —NR4— (R4 is a hydrogen atom or a substituent), and A is an optionally substituted C1-6 alkylene group) or a salt thereof.
    Type: Application
    Filed: March 30, 2015
    Publication date: January 19, 2017
    Applicant: NAGASAKI UNIVERSITY
    Inventors: Yoshimasa TANAKA, Yuki SAKAI, Satoshi MIZUTA, Hiroshi UEDA
  • Patent number: 9534267
    Abstract: According to an embodiment, an induction heating coil includes a heating conductor portion which is formed of a conductor member and has a zigzag shape in which a bent portion opened to one side in a first direction and a bent portion opened to the other side in the first direction are alternately continuously arranged in opposite directions along a second direction crossing the first direction.
    Type: Grant
    Filed: January 27, 2012
    Date of Patent: January 3, 2017
    Assignee: Neturen Co., Ltd.
    Inventors: Yoshimasa Tanaka, Yoshitaka Misaka, Yuji Asano