Patents by Inventor Yoshimi Ohyabu

Yoshimi Ohyabu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Sol for tissue perforation closure, ulcer protection, and vascular embolization
    Patent number: 11559602
    Abstract: The purpose of the present invention is to provide an injectable sol into a body, suited for delivery through a catheter, and usable for tissue perforation closure, ulcer protection, or vascular embolization. Provided are a sol for tissue perforation closure, a sol for ulcer protection, and a sol for vascular embolization, each containing from 0.6 mass % to 3 mass % of a collagen, water, from 200 mM to 330 mM sodium chloride, and a buffer and having a pH from 6.0 to 9.0.
    Type: Grant
    Filed: November 16, 2017
    Date of Patent: January 24, 2023
    Assignees: Tokyo Metropolitan Industrial Technology Research Institute, National University Corporation Gunma University
    Inventors: Toshio Uraoka, Naohisa Yahagi, Shunji Yunoki, Yoshimi Ohyabu, Takefumi Narita
  • Collagen sol for submucosal local injection
    Patent number: 10933171
    Abstract: Object of the present invention is to provide a safe sol for submucosal local injection which gels and creates a mucosal elevation having a high retention rate of mucosal elevation height when locally injected into a digestive submucosa. Provided is a sol for submucosal local injection containing from 0.2 mass % to 1.2 mass % of a collagen, water, a buffer, and from 200 mM to 420 mM sodium chloride.
    Type: Grant
    Filed: November 16, 2017
    Date of Patent: March 2, 2021
    Assignees: Tokyo Metropolitan Industrial Technology Research Institute, National University Corporation Gunma University
    Inventors: Toshio Uraoka, Naohisa Yahagi, Shunji Yunoki, Yoshimi Ohyabu, Takefumi Narita
  • Gelatin, chemically modified product thereof, aqueous composition and medical laminate containing same, production method for medical laminate, and cell sheet isolation method
    Patent number: 10815393
    Abstract: A gelatin or a chemically modified product thereof contains 10 to 50% by mass of a high-molecular weight component, and a low-molecular weight component in such an amount that a value obtained by subtracting a low-molecular weight component content from a high-molecular weight component content is greater than or equal to 0% by mass.
    Type: Grant
    Filed: October 18, 2016
    Date of Patent: October 27, 2020
    Assignees: TOKYO METROPOLITAN INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE, NITTA GELATIN INC.
    Inventors: Yoshimi Ohyabu, Shunji Yunoki, Hirosuke Hatayama, Masataka Ida, Yosuke Hiraoka
  • Sol for Occluding Holes in Living Tissue, Protecting Ulcers, and Treating Vascular Embolization
    Publication number: 20190343992
    Abstract: The purpose of the present invention is to provide an injectable sol into a body, suited for delivery through a catheter, and usable for tissue perforation closure, ulcer protection, or vascular embolization. Provided are a sol for tissue perforation closure, a sol for ulcer protection, and a sol for vascular embolization, each containing from 0.6 mass % to 3 mass % of a collagen, water, from 200 mM to 330 mM sodium chloride, and a buffer and having a pH from 6.0 to 9.0.
    Type: Application
    Filed: November 16, 2017
    Publication date: November 14, 2019
    Inventors: Toshio Uraoka, Naohisa Yahagi, Shunji Yunoki, Yoshimi Ohyabu, Takefumi Narita
  • Collagen Sol for Submucosal Local Injection
    Publication number: 20190290808
    Abstract: Object of the present invention is to provide a safe sol for submucosal local injection which gels and creates a mucosal elevation having a high retention rate of mucosal elevation height when locally injected into a digestive submucosa. Provided is a sol for submucosal local injection containing from 0.2 mass % to 1.2 mass % of a collagen, water, a buffer, and from 200 mM to 420 mM sodium chloride.
    Type: Application
    Filed: November 16, 2017
    Publication date: September 26, 2019
    Inventors: Toshio Uraoka, Naohisa Yahagi, Shunji Yunoki, Yoshimi Ohyabu, Takefumi Narita
  • GELATIN, CHEMICALLY MODIFIED PRODUCT THEREOF, AQUEOUS COMPOSITION AND MEDICAL LAMINATE CONTAINING SAME, PRODUCTION METHOD FOR MEDICAL LAMINATE, AND CELL SHEET ISOLATION METHOD
    Publication number: 20180312726
    Abstract: A gelatin or a chemically modified product thereof contains 10 to 50% by mass of a high-molecular weight component, and a low-molecular weight component in such an amount that a value obtained by subtracting a low-molecular weight component content from a high-molecular weight component content is greater than or equal to 0% by mass.
    Type: Application
    Filed: October 18, 2016
    Publication date: November 1, 2018
    Inventors: Yoshimi OHYABU, Shunji YUNOKI, Hirosuke HATAYAMA, Masataka ODA, Yosuke HIRAOKA
  • METHOD FOR CARTILAGE TISSUE REGENERATION VIA SIMULATED MICROGRAVITY CULTURE USING SCAFFOLDS
    Publication number: 20100221835
    Abstract: This invention relates to a method for cartilage tissue engineering using scaffolds in simulated microgravity culture. This invention enables engineering of homogeneous cartilage tissue using bone marrow cells in a more rapid manner in a simulated microgravity environment, while allowing control of the configuration of the resulting cartilage tissue.
    Type: Application
    Filed: June 15, 2006
    Publication date: September 2, 2010
    Applicant: NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY
    Inventors: Junzo Tanaka, Yoshito Ikada, Yoshimi Ohyabu, Toshimasa Uemura