Patents by Inventor Yoshimi Wakai

Yoshimi Wakai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Therapeutic combination of a pneumocandin derivative and an antifungal agent
    Patent number: 7375081
    Abstract: There is described antifungal combination use of known antifungal agents such as the azoles or polyenes in combination with a lipopeptide compound antifungal agent. More particularly, the invention relates to antifungal combination use of azoles such as fluconazole, voriconazole, itraconazole, ketoconazole, miconazole, ER 30346 and SCH 56592; polyenes such as amphotericin B, nystatin, liposomal and lipid forms thereof such as Abelcet, AmBisome and Amphocil; purine or pyrimidine nucleotide inhibitors such as flucytosine; or polyoxins such as nikkomycins, in particular nikkomycin Z or nikkomycin X; other chitin inhibitors; elongation factor inhibitors such as sordarin and analogs thereof; mannan inhibitors such as predamycin, bactericidal/permeability-inducing (BPI) protein products such as XMP.97 or XMP.127; or complex carbohydrate antifungal agents such as CAN-296; with a lipopeptide compound [I] as described herein.
    Type: Grant
    Filed: January 21, 2005
    Date of Patent: May 20, 2008
    Assignee: Astellas Pharma Inc.
    Inventors: Fumiaki Ikeda, Kazumi Otomo, Yoshimi Wakai, Satoru Matsumoto
  • Antifungal combination use
    Publication number: 20050124536
    Abstract: There is described antifungal combination use of known antifungal agents such as the azoles or polyenes in combination with a lipopeptide compound antifungal agent. More particularly, the invention relates to antifungal combination use of azoles such as fluconazole, voriconazole, itraconazole, ketoconazole, miconazole, ER 30346 and SCH 56592; polyenes such as amphotericin B, nystatin, liposomal and lipid forms thereof such as Abelcet, AmBisome and Amphocil; purine or pyrimidine nucleotide inhibitors such as flucytosine; or polyoxins such as nikkomycins, in particular nikkomycin Z or nikkomycin X; other chitin inhibitors; elongation factor inhibitors such as sordarin and analogs thereof; mannan inhibitors such as predamycin, bactericidal/permeability-inducing (BPI) protein products such as XMP.97 or XMP.127; or complex carbohydrate antifungal agents such as CAN-296; with a lipopeptide compound [I] as described herein.
    Type: Application
    Filed: January 21, 2005
    Publication date: June 9, 2005
    Applicant: Fujisawa Pharmaceutical Co., Ltd.
    Inventors: Fumiaki Ikeda, Kazumi Otomo, Yoshimi Wakai, Satoru Matsumoto
  • Combination of a cyclic hexapeptide with antifungal drugs for treatment of fungal pathogens
    Patent number: 6875740
    Abstract: There is described antifungal combination use of known antifungal agents such as the azoles or polyenes in combination with a lipopeptide compound antifungal agent. More particularly, the invention relates to antifungal combination use of azols such as fluconazole voriconazole, itraconazole, ketoconazole, miconazole, ER 30346 and SCH 56592; polyenes such as amphotericin B, nystatin, liposomal and lipid forms thereof such as Abelcet, AmBisome and Amphocil; purine or pyrimidine nucleotide inhibitors such as flucytosine; or polyoxins such as nikkomycins, in particular nikkomycin Z or nikkomycin X; other chitin inhibitors; elongation factor inhibitors such as sordarin and analogs thereof; mannan inhibitors such as predamycin, bactericidal/permeability-inducing (BPI) protein products such as XMP.97 or XMP.127; or complex carbohydrate antifungal agents such as CAN-296; with a lipopeptide compound (I) as described herein.
    Type: Grant
    Filed: May 24, 2000
    Date of Patent: April 5, 2005
    Assignee: Fujisawa Pharmaceutical Co. Ltd.
    Inventors: Fumiaki Ikeda, Kazumi Otomo, Yoshimi Wakai, Satoru Matsumoto
  • Use
    Publication number: 20030017975
    Abstract: The present invention is relating to a new use of an immunosuppressant, for increasing an antifungal activity of a lipopeptide compound.
    Type: Application
    Filed: June 11, 2002
    Publication date: January 23, 2003
    Inventors: Fumiaki Ikeda, Kazumi Otomo, Satoru Matsumoto, Yoshimi Wakai, Noriko Teratani
  • Composition for prevention and (or) treatment of Aids
    Patent number: 5229368
    Abstract: A method for treatment of Lymphadenopathy, AIDS and AIDS related complex which comprises administering FK-565 or its pharmaceutically acceptable salt and AZT.
    Type: Grant
    Filed: April 10, 1991
    Date of Patent: July 20, 1993
    Assignee: Fujisawa Pharmaceutical Co., Ltd.
    Inventors: Yoshiko Yokota, Yasuhiro Mine, Yoshimi Wakai
  • Composition for prevention and (or) treatment of AIDS
    Patent number: 5059592
    Abstract: A method for treatment of Lymphadenopathy which comprises administering FK-565 or its pharmaceutically acceptable salt and AZT in a ratio of about 1:10-2,000 by weight to an individual in need therefore.
    Type: Grant
    Filed: July 20, 1988
    Date of Patent: October 22, 1991
    Assignee: Fujisawa Pharmaceutical Co., Ltd.
    Inventors: Yoshiko Yokota, Yasuhiro Mine, Yoshimi Wakai