Patents by Inventor Yoshimitsu Komatsu

Yoshimitsu Komatsu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Glucopyranosyloxypyrazole derivatives and medicinal use thereof
    Patent number: 7189702
    Abstract: The present invention provides glucopyranosyloxypyrazole derivatives represented by the general formula: wherein one of Q and T represents a group represented by the general formula: while the other represents a lower alkyl group or a halo(lower alkyl) group; R1 represents a hydrogen atom, an optionally substituted lower alkyl group, a lower alkenyl group, a cyclic lower alkyl group, etc.; R2 represents a hydrogen atom, an optionally substituted lower alkyl group, a lower alkoxy group, a lower alkenyl group, a cyclic lower alkyl group, a cyclic lower alkoxy group, etc., which exert an excellent inhibitory activity in human SGLT2, and therefore are useful as drugs for the prevention or treatment of a disease associated with hyperglycemia such as diabetes, diabetic complications or obesity, pharmaceutically acceptable salts thereof or prodrugs thereof, production intermediates thereof and pharmaceutical uses thereof.
    Type: Grant
    Filed: February 22, 2006
    Date of Patent: March 13, 2007
    Assignee: Kissei Pharmaceutical Co., Ltd.
    Inventors: Toshihiro Nishimura, Nobuhiko Fushimi, Hideki Fujikura, Kenji Katsuno, Yoshimitsu Komatsu, Masayuki Isaji
  • Glucopyranosyloxypyrazole derivatives and medicinal use thereof
    Patent number: 7087579
    Abstract: The present invention provides glucopyranosyloxypyrazole derivatives represented by the general formula: wherein one of Q and T represents a group represented by the general formula: while the other represents a lower alkyl group or a halo(lower alkyl) group; R1 represents a hydrogen atom, an optionally substituted lower alkyl group, a lower alkenyl group, a cyclic lower alkyl group, etc.; R2 represents a hydrogen atom, an optionally substituted lower alkyl group, a lower alkoxy group, a lower alkenyl group, a cyclic lower alkyl group, a cyclic lower alkoxy group, etc., which exert an excellent inhibitory activity in human SGLT2, and therefore are useful as drugs for the prevention or treatment of a disease associated with hyperglycemia such as diabetes, diabetic complications or obesity, pharmaceutically acceptable salts thereof or prodrugs thereof, production intermediates thereof and pharmaceutical uses thereof.
    Type: Grant
    Filed: February 26, 2002
    Date of Patent: August 8, 2006
    Assignee: Kissei Pharmaceutical Co., Ltd.
    Inventors: Toshihiro Nishimura, Nobuhiko Fushimi, Hideki Fujikura, Kenji Katsuno, Yoshimitsu Komatsu, Masayuki Isaji
  • Glucopyranosyloxypyrazole derivatives and medicinal use thereof
    Publication number: 20060142209
    Abstract: The present invention provides glucopyranosyloxypyrazole derivatives represented by the general formula: wherein one of Q and T represents a group represented by the general formula: while the other represents a lower alkyl group or a halo(lower alkyl) group; R1 represents a hydrogen atom, an optionally substituted lower alkyl group, a lower alkenyl group, a cyclic lower alkyl group, etc.; R2 represents a hydrogen atom, an optionally substituted lower alkyl group, a lower alkoxy group, a lower alkenyl group, a cyclic lower alkyl group, a cyclic lower alkoxy group, etc., which exert an excellent inhibitory activity in human SGLT2, and therefore are useful as drugs for the prevention or treatment of a disease associated with hyperglycemia such as diabetes, diabetic complications or obesity, pharmaceutically acceptable salts thereof or prodrugs thereof, production intermediates thereof and pharmaceutical uses thereof.
    Type: Application
    Filed: February 22, 2006
    Publication date: June 29, 2006
    Inventors: Toshihiro Nishimura, Nobuhiko Fushimi, Hideki Fujikura, Kenji Katsuno, Yoshimitsu Komatsu, Masayuki Isaji
  • Glycopyranosyloxypyrazole derivatives and medicinal use thereof
    Publication number: 20040132669
    Abstract: The present invention provides glucopyranosyloxypyrazole derivatives represented by the general formula: 1
    Type: Application
    Filed: February 19, 2004
    Publication date: July 8, 2004
    Inventors: Toshihiro Nishimura, Nobuhiko Fushimi, Hideki Fujikura, Kenji Katsuno, Yoshimitsu Komatsu, Masayuki Isaji