Patents by Inventor Yoshinobu Manome

Yoshinobu Manome has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Analysis method and ?-lactam antibiotic resistance evaluation method
    Patent number: 11435352
    Abstract: In an analysis method of the present invention, a compound represented by the following formula (I) as a matrix is mixed into an analysis target sample and the mixture is subjected to matrix-assisted laser desorption ionization mass spectrometry. In the formula (I), R is an alkyl group having 3-11 carbon atoms. The analysis target sample is a substance for which whether or not ?-lactamase is contained is to be determined. Analysis targets include, for example, bacteria and an extract from bacteria.
    Type: Grant
    Filed: February 13, 2019
    Date of Patent: September 6, 2022
    Assignee: Shimadzu Corporation
    Inventors: Tadayuki Iwase, Yoshinobu Manome, Yoshimitsu Mizunoe, Kouki Fujioka, Yuko Fukuyama
  • ANALYSIS METHOD AND B-LACTAM ANTIBIOTIC RESISTANCE EVALUATION METHOD
    Publication number: 20190250162
    Abstract: In an analysis method of the present invention, a compound represented by the following formula (I) as a matrix is mixed into an analysis target sample and the mixture is subjected to matrix-assisted laser desorption ionization mass spectrometry. In the formula (I), R is an alkyl group having 3-11 carbon atoms. The analysis target sample is a substance for which whether or not ?-lactamase is contained is to be determined. Analysis targets include, for example, bacteria and an, extract from bacteria.
    Type: Application
    Filed: February 13, 2019
    Publication date: August 15, 2019
    Applicant: Shimadzu Corporation
    Inventors: Tadayuki IWASE, Yoshinobu Manome, Yoshimitsu Mizunoe, Kouki Fujioka, Yuko Fukuyama
  • Articular cartilage imaging composition
    Patent number: 10143762
    Abstract: Provided is an articular cartilage imaging composition which can clearly distinguishably visualize a normal site and an abnormal site, i.e., a degenerative site, in articular cartilage. The articular cartilage imaging composition contains a positively charged molecule, which is labeled with a labeling molecule.
    Type: Grant
    Filed: December 8, 2014
    Date of Patent: December 4, 2018
    Assignee: Mercury Assel Management Co., Ltd.
    Inventors: Shuichi Mizuno, Nobuaki Kawaguchi, Akihiro Tsuchiya, Yoshinobu Manome
  • Articular Cartilage Imaging Composition
    Publication number: 20170157271
    Abstract: Provided is an articular cartilage imaging composition which can clearly distinguishably visualize a normal site and an abnormal site, i.e., a degenerative site, in articular cartilage. The articular cartilage imaging composition contains a positively charged molecule, which is labeled with a labeling molecule.
    Type: Application
    Filed: December 8, 2014
    Publication date: June 8, 2017
    Inventors: Shuichi MIZUNO, Nobuaki KAWAGUCHI, Akihiro TSUCHIYA, Yoshinobu MANOME
  • Method of enhancing the effectiveness of DCK phosphorylated molecules
    Patent number: 6423692
    Abstract: A method of increasing the effectiveness of molecules that can be phosphorylated by dCK is described. This method involves transducing cells with the gene for deoxycytidine kinase which can chemosensitize the cell to molecules that are phosphorylated by dCK.
    Type: Grant
    Filed: April 24, 1998
    Date of Patent: July 23, 2002
    Assignee: Dana-Farber Cancer Institute, Inc.
    Inventors: Howard A. Fine, Donald Kufe, Yoshinobu Manome
  • METHOD OF ENHANCING THE EFFECTIVENESS OF DCK PHOSPHORYLATED MOLECULES
    Publication number: 20010012835
    Abstract: A method of increasing the effectiveness of molecules that can be phosphorylated by dCK is described. This method involves transducing cells with the gene for deoxycytidine kinase which can chemosensitize the cell to molecules that are phosphorylated by dCK.
    Type: Application
    Filed: April 24, 1998
    Publication date: August 9, 2001
    Inventors: HOWARD A FINE, DONALD W. KUFE, YOSHINOBU MANOME