Abstract: A compound useful as an active ingredient of a pharmaceutical composition for treatment of cancer related to activation of immune cells or cancer resistant to anti-PD-1 antibody/anti-PD-L1 antibody therapy is provided. The present inventors have conducted studies on a compound useful as an active ingredient of a pharmaceutical composition for treatment of cancer related to activation of immune cells or cancer resistant to anti-PD-1 antibody/anti-PD-L1 antibody therapy, and confirmed that a heteroaryl carboxamide compound has DGK ? (DGKzeta) inhibitory effect, leading to completion of the present invention. The heteroaryl carboxamide compound of the present invention has DGK ? inhibitory effect, and can be used as a therapeutic agent for treatment of cancer related to activation of immune cells or cancer resistant to anti-PD-1 antibody/anti-PD-L1 antibody therapy.

Abstract: An aluminum alloy has high thermal conductivity without requiring an addition of metal elements such as iron and a method for producing the aluminum alloy. The aluminum alloy is obtained from a semi-solid material with a chemical composition containing 2 to 6 wt % of silicon (Si) and 0.7 wt % or less of magnesium (Mg), with the balance being aluminum (Al) and unavoidable impurities. It has a granular crystalline structure. The aluminum alloy is produced by a heating step of semi-solid material. A forming step is performed with semi-solid material obtained in the heating step S1. After the forming step, a heat treatment step is performed at 190° C. to 290° C. for 1 to 5 hours.

Abstract: A thermal transfer image-receiving sheet which does not cause printing failure while being provided with tear-off lines. The sheet includes a dye-receiving layer on one side of a backing sheet, a tear-off line provided crossing the sheet along a width direction of the sheet and roller contact areas configured to contact a transport roller of a printer provided on opposite sides in the width direction. In each of the roller contact areas on the opposite sides, the tear-off line is not parallel to the width direction of the thermal transfer image-receiving sheet in an area occupying half or more of the roller contact area in the width direction, and when that segment of the tear-off line which is not parallel to the width direction of the thermal transfer image-receiving sheet has one or more bends in the roller contact area, all the bends are bent at obtuse angles.

Abstract: An aluminum alloy has high thermal conductivity without requiring an addition of metal elements such as iron and a method for producing the aluminum alloy. The aluminum alloy is obtained from a semi-solid material with a chemical composition containing 2 to 6 wt % of silicon (Si) and 0.7 wt % or less of magnesium (Mg), with the balance being aluminum (Al) and unavoidable impurities. It has a granular crystalline structure. The aluminum alloy is produced by a heating step of semi-solid material. A forming step is performed with semi-solid material obtained in the heating step S1. After the forming step, a heat treatment step is performed at 190° C. to 290° C. for 1 to 5 hours.

Abstract: A gradation representing method capable of representing a wide range of high-quality gradation is provided. A gradation representing method of a predetermined unit region 1 by changing area ratio of ink to be recorded in the unit region 1, wherein the gradation of the unit region 1 is represented by recording a first ink recorded at an area ratio of almost 100% in the unit region and a second ink with changing area ratio are recorded overlappedly in the unit region 1.

Abstract: Disclosed is an image forming method comprising the steps of: providing a print output by a nonsilver photographic color hard copy recording system; providing a protective layer transfer sheet comprising a thermally transferable protective layer having a single or multi-layer structure separably provided on a substrate sheet; putting the print and the protective layer transfer sheet on top of each other and thermally transferring the protective layer onto an image in the print so as to cover at least the printed portion in the print; and separating the substrate sheet from the protective layer transfer sheet.

Abstract: Disclosed is an image forming method comprising the steps of: providing a print output by a nonsilver photographic color hard copy recording system; providing a protective layer transfer sheet comprising a thermally transferable protective layer having a single or multi-layer structure separably provided on a substrate sheet; putting the print and the protective layer transfer sheet on top of each other and thermally transferring the protective layer onto an image in the print so as to cover at least the printed portion in the print; and separating the substrate sheet from the protective layer transfer sheet.

Abstract: The present invention provides a thermally transferable image protective sheet, that can be thermally transferred to form a protective layer which can protect an image in a record immediately produced by a nonsilver photographic color hard copy recording method, can impart lightfastness and other properties to the resultant record and, in the case of records for outdoor applications or the like, can prevent dazzle caused by the reflection of light at the time of viewing of the image, a method for protective layer formation, and a record produced by the method for protective layer formation. The thermally transferable image protective sheet comprises a support and a thermally transferable resin layer having a single-layer or multilayer structure stacked on the support so as to be separable from the surface of the support. In use, thermally transferable resin layer is thermally transferred on an image in a print so as to cover at least the printed portion in the print followed by the separation of the support.

Abstract: Disclosed is an image forming method comprising the steps of: providing a print output by a nonsilver photographic color hard copy recording system; providing a protective layer transfer sheet comprising a thermally transferable protective layer having a single or multi-layer structure separably provided on a substrate sheet; putting the print and the protective layer transfer sheet on top of each other and thermally transferring the protective layer onto an image in the print so as to cover at least the printed portion in the print; and separating the substrate sheet from the protective layer transfer sheet.

Abstract: Thermal transfer image-receiving sheet comprising paper as a substrate sheet and provided on the substrate sheet in the following order, and expanded layer and a receptive layer, and undercoat layer being provided between the substrate sheet and the expanded layer. Also disclosed is a thermal transfer image-receiving sheet including a substrate sheet of paper composed mainly of pulp and, provided on the substrate sheet in the following order, and expanded layer, an intermediate layer and a receptive layer, the intermediate layer having been formed by coated an aqueous coating solution.

Abstract: A method of manufacturing a thermal transfer image receiving sheet which comprises a substrate made of a paper comprising essentially pulp, an intermediate layer disposed on said substrate and a receptor layer disposed on said intermediate layer, comprising steps of: forming said intermediate layer having a structure comprising fine pores on said substrate, and forming said receptor layer on said intermediate layer.

Abstract: A thermal transfer image-receiving sheet is provided which causes none of a dimensional change, curling, misregistration of image and can produce a printed image having satisfactory image quality and density. The thermal transfer image-receiving sheet comprises: a paper substrate; and a dye-receptive layer provided on one side of the substrate, a water vapor barrier layer composed mainly of a resin being provided on at least the side of the thermal transfer image-receiving sheet remote from the dye-receptive layer.

Abstract: A thermal transfer image-receiving sheet is provided which does not cause destruction of a heat-insulating, porous layer at the time of formation of a dye-receptive layer, has no fear of the dye-receptive layer being separated, and in addition can produce a printed image having satisfactory image quality and density. The thermal transfer image-receiving sheet comprise: a paper substrate; and, provided on the substrate in the following order, a heat-insulating, porous layer composed mainly of a resin, a barrier layer, and a dye-receptive layer, the barrier layer comprising at least a mixture of polyvinyl alcohol with a polyurethane resin, the weight ratio on solid basis of polyvinyl alcohol to polyurethane resin being 10:100 to 80:100.

Abstract: A thermal transfer image-receiving sheet including a substrate sheet and a dye-receptive layer provided directly or through an intermediate layer on one surface of the substrate sheet, the dye-receptive layer having a surface roughness of center line average height Ra=1.0-4.0 .mu.m, maximum height R.sub.max =15.0-37.0 .mu.m and 10-point average height Rz=10.0-30.0 .mu.m. Also disclosed is a thermal transfer image-receiving sheet comprising paper as a substrate sheet and, provided on the substrate sheet in the following order, an expanded layer and a receptive layer, an undercoat layer being provided between the substrate sheet and the expanded layer. Also disclosed is a thermal transfer image-receiving sheet comprising a substrate sheet of paper composed mainly of pulp and, provided on the substrate sheet in the following order, an expanded layer, an intermediate layer and a receptive layer, the intermediate layer having been formed by coating an aqueous coating solution.

Abstract: A roll-type heat transfer image-receiving sheet comprising a wind-up cylinder and a heat transfer image-receiving sheet which comprises at least a substrate and a coloring material-receiving layer provided thereon, the heat transfer image-receiving sheet being wound around the wind-up cylinder, wherein the maximum surface roughness of the wind-up cylinder in the longitudinal direction thereof is controlled to 40 micrometers or less; the wind-up cylinder is prepared by using pulp as a main component, and a cushioning material is provided between the wind-up cylinder and the heat transfer image-receiving sheet; a lead sheet is provided to the leading end of the heat transfer image-receiving sheet so that the image-receiving sheet can be easily led through a printer; and the heat transfer image-receiving sheet is wound around the wind-up cylinder with the coloring material-receiving sheet outside so that curl will not remain in the image-receiving sheet and that curl will not be developed during a printing proce