Abstract: The invention provides a body fluid treatment method for selective ex vivo killing of malignant lymphoma cells, leukemia cells or activated macrophages in a body fluid, the body fluid treatment method comprising: an addition step wherein a compound represented by formula (I) below is added to a body fluid containing malignant lymphoma cells, leukemia cells or activated macrophages that has been removed from the body, to yield an addition mixture; and an excitation step wherein the addition mixture is irradiated with excitation light to excite the compound. According to the invention, there is provided a method for selective ex vivo killing of malignant lymphoma cells, leukemia cells or activated macrophages in a body fluid while avoiding adverse effects on normal cells.

Abstract: Various diagnostics with the application of photodynamic diagnosis/therapy (photodynamic therapy: PDT) wherein use is made of highly selective uptake of an iminochlorinaspartic acid derivative or its pharmacologically acceptable salt in neovessels and selective uptake thereof in cancer cells. More specifically, remedies for rheumatism, remedies for inflammatory keratosis, agents for confirming the location of a sentinel lymph node and diagnostics for cancer metastasis which contain as the active ingredient an iminochlorinaspartic acid derivative represented by the following formula (I) or its pharmacologically acceptable salt: (I) wherein Asp represents aspartate.

Abstract: The present invention provides the porphyrin compound which is used for photodynamic diagnosis and/or treatment for animals, and the photodynamic diagnostic and/or therapeutic agent for animals.

Abstract: The present invention provides the porphyrin compound having nitroimidazole in the molecule, which is used for diagnosis and/or treatment of cancer in magnetic resonance imaging (MRI) and/or radiotherapy as well as for DDS therapy. The porphyrin compound of the present invention shows no phototoxicity, and represented by the following formula: [wherein, R1 and R2 are —CH═CH2 or —CH(CH3)—OH, —CH(CH3)—O—(CH2)n—NH—Ra; R3 is hydrogen atom or —CO—(CH2)m—COOH; and M is transition metal of Mn, Fe, Co or Cu], (in which, Ra is hydrogen atom or the group represented by the following formula: n and m are the integer 2 or 3), or a pharmaceutically acceptable salt thereof.

Abstract: The present invention provides the porphyrin compound which is used for photodynamic diagnosis and/or treatment for animals, and the photodynamic diagnostic and/or therapeutic agent for animals.

Abstract: The present invention provides the porphyrin compound having nitroimidazole in the molecule, which is used for diagnosis and/or treatment of cancer in magnetic resonance imaging (MRI) and/or radiotherapy as well as for DDS therapy.

Abstract: A layered polyamide film includes a polyamide substrate; and an adhesiveness-improving layer provided on at least one surface of the polyamide substrate. The adhesiveness-improving layer includes a graft copolymer of a polyester and an acrylic polymer. Another layered polyamide film includes a printing ink layer, an adhesive layer, and a sealant layer sequentially laminated on the adhesiveness-improving layer. A method for producing such a layered polyamide film includes the step of applying an aqueous dispersion of the graft copolymer of the polyester and the acrylic polymer to at least one surface of the polyamide substrate to form an adhesiveness-improving layer and, if necessary, laminating a printing ink layer, an adhesive layer, and a sealant layer on adhesiveness-improving layer.