Abstract: Compounds represented by the general formula: [wherein R1 represents methoxy, ethyl, methylthio, etc., R2, R3 and R4 each represent hydrogen, a halogen, etc., R5 and R6 each represent —X5—X6—X7 (wherein X5 represents a single bond or —CO—, X6 represents a single bond, —NR3a, etc. and X7 and R3a each represent hydrogen, C1-10 alkyl, etc.), and Ar represents phenyl, pyridyl, etc.], salts thereof and hydrates of the foregoing.

Abstract: A safe and widely-applicable food intake regulator can be provided by using at least one peptide selected from the group consisting of a fish or mammalian melanin-concentrating hormone (MCH) and enzymatic digests thereof, which have the activity to suppress food intake.

Abstract: A compound represented by the following formula (I), or salt thereof exhibits excellent CRF receptor antagonism, and sufficient pharmacological activity, safety and pharmacokinetic properties as a drug. wherein R1 represents the formula -A11-A12; R2 represents tetrahydrofurylmethyl, tetrahydropyranylmethyl or tetrahydropyranyl; A11 represents a single bond, methylene or 1,2-ethylene; A12 represents C1-6 alkyl, C3-6 cycloalkyl or C3-6 cycloalkyl having methyl; R3 represents methoxy, cyano, cyclobutyloxymethyl, methoxymethyl or ethoxymethyl; and R4 represents methoxy or chlorine.

Abstract: A method is designed for emphasizing a howling frequency component of a sound signal observed in an acoustic feedback system during an observation period having a predetermined length.

Abstract: A CCD driver circuit adjusts and supplies pulse-type signals to a CCD in order to adjust the sensitivity of the CCD. A metering circuit meters a signal output from the CCD. A sensitivity control circuit controls the sensitivity of the CCD by controlling the sensitivity multiplication factor of the CCD based on a metering result by the metering circuit. A metering correcting circuit corrects a metering result from the metering circuit based on a charge multiplication factor from the sensitivity control circuit. An aperture control circuit controls an aperture based on a metering signal corrected by the metering correcting circuit. Thus, an image of an object of which strength of light largely varies can be obtained as an image under a proper dimming state.

Abstract: The present invention provides a novel compound having an excellent corticotrophin-releasing-factor receptor antagonistic activity. That is, it provides a compound represented by the following formula or a salt thereof. Wherein R1 denotes a hydrogen atom, a C1-6 alkyl group, a C1-6 alkoxy group and the like; R2 denotes a halogen atom, a cyano group, a nitro group, a C1-10 alkyl group, a C2-10 alkenyl group, C2-10 alkynyl group and the like; R3 denotes a C6-14 aromatic hydrocarbon cyclic group or a 5- to 14-membered aromatic heterocyclic group, each of which may have a substituent; and X, Y and X are independent of each other and each denotes N or CR4 (wherein R4 denotes a hydrogen atom, a halogen atom, a cyano group, a nitro group, an optionally halogenated C1-6 alkyl group and the like) and, in this case, at least two of X, Y and Z denote CR4.

Abstract: An exhaust gas purifying system reliably detects an amount of accumulated particulates, lengthens forced regeneration intervals, and improves fuel efficiency. The exhaust gas purifying system comprises: a particulate filter 22 disposed in an exhaust system of an internal combustion engine 2 and collecting particulates from exhaust gas, and an NO2 generating unit 21 upstream of or in the particulate filter 22; a discharged particulate amount calculating unit A1 calculates an amount Me of discharged particulates on the basis of an excess air ratio ?; a burnt particulate amount calculating unit A2 calculates an amount Mb of burnt particulates on the basis of the temperature of exhaust gas in front of the particulate filter or the temperature of the particulate filter; and a particulate accumulation amount calculating unit calculates an amount Ma of accumulated particulates on the basis of the amount Me of discharged particulates or the amount Mb of burnt particulates.

Abstract: An image processor includes a filter process circuit for executing a filtering of image data picked up by an image pickup unit with a plurality of spatial filters, a brightness calculation circuit for calculating a brightness in a local area of the image data, a weighting circuit for weighting an output of the filter process circuit in accordance with an output of the filter process circuit and/or an output of the brightness calculation circuit, and an inverse filter process circuit for executing an inverse filter process with respect to an output of the weighting circuit to generate process image data.

Abstract: Illumination light supplied from an illumination light supplying unit that can selectively supply a plurality kinds of illumination lights whose wavelengths fall in different regions is supplied to an object. A signal picking up an image of the object is received by a programmable circuit unit that is programmably constructed based on circuit data, and then subjected to signal processing. A circuit data holding unit holds a plurality kinds of circuit data to be used for the programmable circuit unit. A control unit selects circuit data, which is used for the programmable circuit unit, from among all the circuit data items held in the circuit data holding unit corresponding to illumination light supplied from the illumination light supplying unit.

Abstract: An image pick-up apparatus includes an image pick-up device which picks-up an image of a subject and outputs an image signal, a first-amplitude changing portion which varies an amplitude of the image signal outputted form the image pick-up device, a second-amplitude changing portion which varies the amplitude of the image signal to be outputted, a comparing portion which compares the amplitude of the image signal with a value of a target amplitude, and a control portion which controls the first- and second-amplitude changing portions based on the comparison result of the comparing portion and changes the amplitude of the image signal so that it is approximate to the target amplitude so that an observed image of the subject displayed on display means has a desired brightness.

Abstract: An engine control system includes an EGR device 10 which connects an exhaust passage Ex and an intake passage I and has an EGR valve; an intake throttle valve 41 placed in the intake passage I; and an engine control unit which is provided with an engine operation data calculator A1 accumulating mileages of a vehicle or an engine operation period, a fuel injection controller A2 controlling a fuel injection amount and a fuel injection timing, an EGR controller A3 controlling an opening of the EGR valve; a throttle valve controller A4 controlling an opening of the intake throttle valve; and an EGR passage cleaning controller A5 which delays a fuel injection timing Tn, increases an opening ? g of the EGR valve, and reduces an opening ? s of the intake throttle valve when the total mileage or the total operation period calculated by the engine operation data calculator becomes equal to a predetermined threshold.

Abstract: An endoscope apparatus includes an endoscope that has a solid-state image-pickup device in which charges are accumulated in order to pick up an object image. The endoscope apparatus further comprises a memory in which a plurality of pieces of information on the accumulation period during which charges are accumulated in the solid-state image-pickup device is stored, and a drive unit that controls the accumulation period, during which charges are accumulated in the solid-state image-pickup device, on the basis of the pieces of information on the accumulation period stored in the memory. The endoscope further includes an optical member whose surface is shaped rotationally asymmetric. Correction information stored in a memory and associated with the optical element is used to correct an output signal of the solid-state image-pickup device.

Abstract: An exchange is provided, the exchange receiving a number of a telephone terminal of a called party, selecting a network from a plurality of connectable networks including the Internet with the number and connecting to the network. In addition, the exchange calls the telephone terminal via a network other than the Internet and connects to the telephone terminal in response to a predetermined operation by a caller during a call via the Internet.

Abstract: A compound represented by the formula: [wherein R1 is methoxy, methylthio, ethyl, etc.; R5 and R6 are each independently cyclopropylmethyl, (4-tetrahydropyranyl)methyl, etc.; and two of R40, R41 and R42 are C1-6 alkoxy while the remaining one is methoxymethyl, etc.], a salt thereof, or a hydrate of the foregoing. This compound has excellent antagonism against corticotropin-releasing factor receptor.

Abstract: There is provided an oxidizing catalyst located in the upstream of the exhaust gas purifying catalyst. The catalyst capacity of the oxidizing catalyst is set so that, in the relationship between a value obtained by dividing exhaust flow velocity by the catalyst capacity (exhaust flow velocity/catalyst capacity) and catalyst activatibility, when the exhaust flow velocity is exhaust flow velocity at the time of idle operation of the internal combustion engine, the catalyst activatibility is maximum (prescribed maximum activation range) and the value obtained by dividing the exhaust flow velocity by the catalyst capacity is maximum or close to the maximum.

Abstract: A compound represented by the formula: [wherein R1 is methoxy, methylthio, ethyl, etc.; R5 and R6 are each independently cyclopropylmethyl, (4-tetrahydropyranyl)methyl, etc.; and two of R40, R41 and R42 are C1-6 alkoxy while the remaining one is methoxymethyl, etc.], a salt thereof, or a hydrate of the foregoing. This compound has excellent antagonism against corticotropin-releasing factor receptor.

Abstract: An engine control system includes an EGR device 10 which connects an exhaust passage Ex and an intake passage I and has an EGR valve; an intake throttle valve 41 placed in the intake passage I; and an engine control unit which is provided with an engine operation data calculator A1 accumulating mileages of a vehicle or an engine operation period, a fuel injection controller A2 controlling a fuel injection amount and a fuel injection timing, an EGR controller A3 controlling an opening of the EGR valve; a throttle valve controller A4 controlling an opening of the intake throttle valve; and an EGR passage cleaning controller A5 which delays a fuel injection timing Tn, increases an opening ? g of the EGR valve, and reduces an opening ? s of the intake throttle valve when the total mileage or the total operation period calculated by the engine operation data calculator becomes equal to a predetermined threshold.

Abstract: In the present invention, an abnormality determination circuit outputs an abnormality determination signal when determining an abnormal pixel, captures images of a synchronization memory F, a synchronization memory G, and a synchronization memory R at the time in a temporary memory. Also, an abnormality position display circuit is controlled to display, in a superimposing manner, a mark indicating a position with the abnormal pixel on the images captured in the temporary memory. Still image data of a normal image marked in the superimposing manner and stored in the temporary memory is outputted to a D/A conversion circuit, and thus displayed in a thumbnail form on a monitor. This allows an area suspected of having abnormal tissue to be easily and reliably identified on a normal color endoscopic image.