Patents by Inventor Yoshio Hayase
Yoshio Hayase has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 6004952Abstract: The object of the present invention is to provide a novel compound which has various biological activities and is useful for medical and animal drugs. The present invention provides a compound represented by the formula: ##STR1## wherein R.sup.1 is COOR.sup.4, CONR.sup.5 R.sup.6, CO--R.sup.7 --OR or CH.sub.2 OR.sup.8 ; R.sup.2 is hydrogen atom, alkyl, aralkyl, heteroaryl, heteroarylalkyl, COR.sup.13, COOR.sup.14, CONR.sup.15 R.sup.16 ; R.sup.3 is hydrogen atom or OR.sup.3 ; a broken line ( - - - ) represents the presence of a double bond when R.sup.3 is oxygen atom and the absence of a double bond when R.sup.3 is OR.sup.3, or a salt or metal chelete thereof.Type: GrantFiled: August 5, 1998Date of Patent: December 21, 1999Assignee: Shinogi & Co., Ltd.Inventors: Yoshio Hayase, Shinobu Kobayashi, Kazuo Ueda, Shigetada Hidaka
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Patent number: 5707838Abstract: The invention is a compound of the formula: ##STR1## wherein M is a bivalent or trivalent metal ion, and X is OH or O.sup..crclbar.. The above compound of the present invention is useful for prevention or treatment of mycoplasmosis.Type: GrantFiled: March 28, 1996Date of Patent: January 13, 1998Assignee: Shionogi & Co., Ltd.Inventors: Reiji Takeda, Shigetada Hidaka, Shinobu Kobayashi, Yoshio Hayase, Mamoru Ozaki, Hiroshi Nakai
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Patent number: 5548078Abstract: A fungicidal composition for agricultural use, which comprises a compound of the formula: ##STR1## wherein R.sup.1 and R.sup.2 are each hydrogen, lower alkyl or cyclo(lower)alkyl; R.sup.3 is lower alkyl or cyclo(lower)alkyl; R.sup.4 and R.sup.5 are each hydrogen, lower alkyl, lower alkoxy, halogen-substituted lower alkyl, lower alkyl-substituted silyl, halogen or nitro; A represents an unsaturated hydrocarbon group, a halogen-substituted unsaturated hydrocarbon group, a phenyl group or a heterocyclic group, among which the phenyl group and the heterocyclic group may be optionally substituted with not more than three substituents; and Z is --CH.sub.2 --, --CH(OH)--, --CO--, --O--, --S--, --NR-- (R being hydrogen or lower alkyl), --CH.sub.2 CH.sub.2 --, --CH.dbd.CH--, ##STR2## --CH.sub.2 O--, --CH.sub.2 S--, --CH.sub.2 SO--, --OCH.sub.2 --, --SCH.sub.2 -- or --SOCH.sub.2 --.Type: GrantFiled: December 20, 1994Date of Patent: August 20, 1996Assignee: Shionogi Seiyaku Kabushiki KaishaInventors: Yoshio Hayase, Takahiro Kataoka, Hideyuki Takenaka, Mitsuhiro Ichinari, Michio Masuko, Toshio Takahashi, Norihiko Tanimoto
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Patent number: 5401877Abstract: A fungicidal composition for agricultural use, which comprises a compound of the formula: ##STR1## wherein R.sup.1 and R.sup.2 are each hydrogen, lower alkyl or cyclo(lower)alkyl; R.sup.3 is lower alkyl or cyclo(lower)alkyl; R.sup.4 and R.sup.5 are each hydrogen, lower alkyl, lower alkoxy, halogen-substituted lower alkyl, lower alkyl-substituted sibyl, halogen or nitro; A represents an unsaturated hydrocarbon group, a halogen-substituted unsaturated hydrocarbon group, a phenyl group or a heterocyclic group, among which the phenyl group and the heterocyclic group may be optionally substituted with not more than three substituents; and Z is --CH.sub.2 --, --CH(OH)--, --CO--, --O--, --S--, --NR-- (R being hydrogen or lower alkyl), --CH.sub.2 CH.sub.2 --, --CH=CH--, ##STR2## --CH.sub.2 O--, --CH.sub.2 S--, --CH.sub.2 SO--, --OCH.sub.2 --, --SCH.sub.2 -- or --SOCH.sub.2 --.Type: GrantFiled: July 22, 1994Date of Patent: March 28, 1995Assignee: Shionogi Seiyaku Kabushiki KaishaInventors: Yoshio Hayase, Takahiro Kataoka, Hideyuki Takenaka, Mitsuhiro Ichinari, Michio Masuko, Toshio Takahashi, Norihiko Tanimoto
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Patent number: 5371223Abstract: A fungicidal composition for agricultural use, which comprises a compound of the formula: ##STR1## wherein R.sup.1 and R.sup.2 are each hydrogen, lower alkyl or cyclo(lower)alkyl; R.sup.3 is lower alkyl or cyclo(lower)alkyl; R.sup.4 and R.sup.5 are each hydrogen, lower alkyl, lower alkoxy, halogen-substituted lower alkyl, lower alkyl-substituted silyl, halogen or nitro; A represents an unsaturated hydrocarbon group, a halogen-substituted unsaturated hydrocarbon group, a phenyl group or a heterocyclic group, among which the phenyl group and the heterocyclic group may be optionally substituted with not more than three substituents; and Z is --CH.sub.2 --, --CH(OH)--, --CO--, --O--, --S--, --NR-- (R being hydrogen or lower alkyl), --CH.sub.2 CH.sub.2 --, --CH.dbd.CH--, ##STR2## --CH.sub.2 O--, --CH.sub.2 S--, --CH.sub.2 SO--, --OCH.sub.2 --, --SCH.sub.2 -- or --SOCH.sub.2 --.Type: GrantFiled: October 8, 1993Date of Patent: December 6, 1994Assignee: Shionogi Seiyaku Kabushiki KaishaInventors: Yoshio Hayase, Takahiro Kataoka, Hideyuki Takenaka, Mitsuhiro Ichinari, Michio Masuko, Toshio Takahashi, Norihiko Tanimoto
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Patent number: 5371222Abstract: A fungicidal composition for agricultural use, which comprises a compound of the formula: ##STR1## wherein R.sup.1 and R.sup.2 are each hydrogen, lower alkyl or cyclo(lower)alkyl; R.sup.3 is lower alkyl or cyclo(lower)alkyl; R.sup.4 and R.sup.5 are each hydrogen, lower alkyl, lower alkoxy, halogen-substituted lower alkyl, lower alkyl-substituted silyl, halogen or nitro; A represents an unsaturated hydrocarbon group, a halogen-substituted unsaturated hydrocarbon group, a phenyl group or a heterocyclic group, among which the phenyl group and the heterocyclic group may be optionally substituted with not more than three substituents; and Z is --CH.sub.2 --, --CH(OH)--, --CO--, --O--, --S--, --NR-- (R being hydrogen or lower alkyl), --CH.sub.2 CH.sub.2 --, --CH.dbd.CH--, ##STR2## --CH.sub.2 O--, --CH.sub.2 S--, --CH.sub.2 SO--, --OCH.sub.2 --, --SCH.sub.2 -- or --SOCH.sub.2 --.Type: GrantFiled: October 16, 1992Date of Patent: December 6, 1994Assignee: Shionogi Seiyaku Kabushiki KaishaInventors: Yoshio Hayase, Takahiro Kataoka, Hideyuki Takenaka, Mitsuhiro Ichinari, Michio Masuko, Toshio Takahashi, Norihiko Tanimoto
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Patent number: 5360810Abstract: There is disclosed a compound of the formula (I): ##STR1## wherein X is a hydrogen atom or 1 to 5 substituents which may be the same or different and are selected from the group consisting of a hydrogen atom, alkyl, alkenyl, alkynyl, optionally substituted phenyl, an optionally substituted heterocyclic group, alkoxy, alkenyloxy, alkynyloxy, optionally substituted phenoxy, mono-, di- or tri-substituted halogenoalkyl and a halogen atom; Y is CH or N; m is 0 or 1; A is a group of the formula: ##STR2## (wherein R.sup.1 is a hydrogen atom or alkyl; n is 0 or 1; B is O, S or NR.sup.3 ; R.sup.2 and R.sup.3 are the same or different and are a hydrogen atom, alkyl, alkenyl, alkynyl, phenyl, benzyl, acyl or phenacyl). There are also disclosed the production thereof and an agricultural fungicide containing the compound as an active component.Type: GrantFiled: March 18, 1993Date of Patent: November 1, 1994Assignee: Shionogi & Co., Ltd.Inventors: Yoshio Hayase, Hideyuki Takenaka, Norihiko Tanimoto, Michio Masuko, Toshihiko Takahashi
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Patent number: 5248687Abstract: There is disclosed a compound of the formula (I): ##STR1## wherein X is a hydrogen atom or 1 to 5 substituents which may be the same or different and are selected from the group consisting of a hydrogen atom, alkyl, alkenyl, alkynyl, optionally substituted phenyl, an optionally substituted heterocyclic group, alkoxy, alkenyloxy, alkynyloxy, optionally substituted phenoxy, mono-, di- or tri-substituted halogenoalkyl and a halogen atom; Y is CH or N; m is 0 or 1; A is a group of the formula: ##STR2## (wherein R.sup.1 is a hydrogen atom or alkyl; n is 0 or 1; B is O, S or NR.sup.3 ; R.sup.2 and R.sup.3 are the same or different and are a hydrogen atom, alkyl, alkenyl, alkynyl, phenyl, benzyl, acyl or phenacyl). There are also disclosed the production thereof and an agricultural fungicide containing the compound as an active component.Type: GrantFiled: August 3, 1992Date of Patent: September 28, 1993Assignee: Shionogi & Co., Ltd.Inventors: Yoshio Hayase, Hideyuki Takenaka, Norihiko Tanimoto, Michio Masuko, Toshio Takahashi
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Patent number: 5185342Abstract: A fungicidal composition for agricultural use, which comprises a compound of the formula: ##STR1## wherein R.sup.1 and R.sup.2 are each hydrogen, lower alkyl or cyclo(lower)alkyl; R.sup.3 is lower alkyl or cyclo(lower)alkyl; R.sup.4 and R.sup.5 are each hydrogen, lower alkyl, lower alkoxy, halogen-substituted lower alkyl, lower alkyl-substituted silyl, halogen or nitro; A represents an unsaturated hydrocarbon group, a halogen-substituted unsaturated hydrocarbon group, a phenyl group or a heterocyclic group, among which the phenyl group and the heterocyclic group may be optionally substituted with not more than three substituents; and Z is --CH.sub.2 --, --CH(OH)--, --CO--, --O--, --S--, --NR-- (R being hydrogen or lower alkyl), --CH.sub.2 CH.sub.2 --, --CH.dbd.CH--, --CH.sub.2 O--, --CH.sub.2 S--, --CH.sub.2 SO--, --OCH.sub.2 --, --SCH.sub.2 -- or --SOCH.sub.2 --.Type: GrantFiled: May 16, 1990Date of Patent: February 9, 1993Assignee: Shionogi Seiyaku Kabushiki KaishaInventors: Yoshio Hayase, Takahiro Kataoka, Hideyuki Takenaka, Mitsuhiro Ichinari, Michio Masuko, Toshio Takahashi, Norihiko Tanimoto
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Patent number: 5089043Abstract: A heterocyclic oxy-phenoxyacetic acid derivative of the formula: ##STR1## , or its salt, which is useful as a herbicide.Type: GrantFiled: November 6, 1990Date of Patent: February 18, 1992Assignee: Shionogi & Co., Ltd.Inventors: Yoshio Hayase, Kohei Matsumoto, Kazuo Kamei, Kinya Ide, Toshio Takahashi
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Patent number: 4720488Abstract: A compound of the formula: ##STR1## wherein R.sup.1 and R.sup.2 each represent C.sub.1 -C.sub.5 alkoxy or C.sub.1 -C.sub.5 alkylthio, R.sup.3, R.sup.4, R.sup.5 and R.sup.6 each represent hydrogen or C.sub.1 -C.sub.5 alkyl, R.sup.7, R.sup.8 and R.sup.9 each represent hydrogen, C.sub.1 -C.sub.5 alkyl or halogen, and X represents oxygen or sulfur. A process for preparing the compound (I) and a pesticidal composition containing the compound (I) are also provided.Type: GrantFiled: December 8, 1986Date of Patent: January 19, 1988Assignee: Shionogi & Co., Ltd.Inventors: Yoshio Hayase, Mitsuhiro Ichinari, Kazuo Kamei, Junji Taguchi, Katsuaki Oba, Toshio Takahashi
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Patent number: 4695312Abstract: A compound (I) of the formula: ##STR1## (wherein X and Y each is halogen) and herbicidal compositions containing the compound (I) are provided.Type: GrantFiled: March 31, 1986Date of Patent: September 22, 1987Assignee: Shionogi & Co., Ltd.Inventors: Yoshio Hayase, Toshikazu Ohtsuka, Kinya Ide, Toshio Takahashi
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Patent number: 4681874Abstract: Novel thiazinephosphonic acid derivatives (I): ##STR1## wherein R.sup.1 and R.sup.2 each is lower alkoxy, lower alkynyloxy, lower alkylthio, arylthio (e.g., monocyclic aromatic group), or lower alkylamino; R.sup.3 and R.sup.4 each is hydrogen or lower alkyl; R.sup.5, R.sup.6, and R.sup.7 each is hydrogen, lower alyl, lower alkoxy, halogen, or trifluoromethyl; and X is oxygen or sulfur, are disclosed. A method for the production thereof, and pesticides comprising said compounds (I) are provided.Type: GrantFiled: September 6, 1985Date of Patent: July 21, 1987Assignee: Shionogi & Co., Ltd.Inventors: Yoshio Hayase, Mitsuhiro Ichinari, Junji Taguchi, Takeo Ishiguro, Toshio Takahashi
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Patent number: 4663314Abstract: A compound of the formula: ##STR1## wherein R.sup.1 and R.sup.2 are each phenyl optionally substituted by one selected from the group consisting of C.sub.1 -C.sub.5 alkyl, C.sub.1 -C.sub.5 alkoxy, C.sub.1 -C.sub.5 alkylthio, C.sub.1 -C.sub.5 alkylenedioxy, halogen, nitro, and halogeno-C.sub.1 -C.sub.5 alkoxy; R.sup.3 and R.sup.4 are each C.sub.1 -C.sub.5 alkyl; and Z is N or CH. A method for preparing the compound (I) and a pesticidal formulation containing the same are also provided.Type: GrantFiled: May 6, 1986Date of Patent: May 5, 1987Assignee: Shionogi & Co., Ltd.Inventors: Yoshio Hayase, Toshikazu Ohtsuka, Takeo Ishiguro, Toshio Takahashi
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Patent number: 4648898Abstract: Novel triazine derivatives (I) and herbicides are provided. ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, and R.sup.4 each is hydrogen, aliphatic hydrocarbon residue, lower alkoxy-(lower alkyl), cyano-(lower alkyl), or aryl-(lower alkyl); or (R.sup.1 and R.sup.2) or (R.sup.3 and R.sup.4) taken together form lower alkylene.Type: GrantFiled: August 9, 1985Date of Patent: March 10, 1987Assignee: Shionogi & Co., Ltd.Inventors: Yoshio Hayase, Koichi Morita, Kinya Ide, Toshio Takahashi
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Patent number: D376066Type: GrantFiled: June 9, 1994Date of Patent: December 3, 1996Assignee: Tanico CorporationInventors: Tatsuo Taniguchi, Masayuki Fujimori, Yoshio Hayase