Abstract: A method of manufacturing a tablet containing coated granules comprising compressing the coated granules containing biologically active substance and having a temperature exceeding a room temperature, whereby the tablet can be prevented from rupture of a part of a coating film of the granules at the time of tablet compression.

Abstract: A method of manufacturing a tablet containing coated granules comprising compressing the coated granules containing biologically active substance and having a temperature exceeding a room temperature, whereby the tablet can be prevented from rupture of a part of a coating film of the granules at the time of tablet compression.

Abstract: A solid pharmaceutical preparation containing 5 to 50% by weight of ibuprofen and 0.1 to 10% by weight of phenylpropionamide or a pharmaceutically acceptable salt thereof which are stabilized. The solid pharmaceutical preparation can be produced by means of granulating with carriers at least one active ingredient, preferably both ingredients separately into the ibuprofen group and the phenylpropanolamine group, and mixing the former with the latter to enhance the stability of the active ingredients. Preferably, in the phenylpropanolamine group, the amount of any reducing sugar is minimized to such an extent as to maintain the stability of the active ingredient. The above pharmaceutical preparation is suitable for a cold remedy, which has a more excellent pharmacological activity based on ibuprofen, less decomposability of phenylpropanolamine and less change of external appearance of the preparation due to low compatibility between phenylpropanolamine and ibuprofen.

Abstract: A tablet having first and second surfaces opposite to each other and a side surface lying perpendicular to any one of the first and second surfaces. A peripheral tablet edge delimited between each of the first and second surfaces and the side surface is chamfered to provide a respective inclined peripheral edge face over the entire perimeter of the tablet. This tablet also has at least a first generally V-sectioned score defined in the first surface so as to leave two tablet divisions of uniform size on respective sides of the V-sectioned first score. A pair of generally V-sectioned side scores are defined in the side surface of the tablet at respective locations opposite to each other and are continuous with opposite ends of the V-sectioned first score. The tablet can be divided along the V-sectioned score in the first surface by the application of a minimized finger pressure. The tablet of the invention is particularly suited to the pharmaceutical field.

Abstract: A method for sensing a human body has the steps of projecting infra-red rays from a projector, receiving infra-red rays reflected from a background and a human body by a photo-sensor, deriving a difference between a reflection amount from the background and that from the human body on the basis of an output from the photo-sensor by the action of first and second integrator circuits, and outputting a human body sense signal from a response circuit when the difference in the reflection amount is held at a predetermined period of time. The first integrator circuit has a relatively small time constant, while the second integrator circuit has a relatively large time constant.