Patents by Inventor Yoshio Ohara

Yoshio Ohara has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230322679
    Abstract: A method for producing a drug substance of crystalline pitavastatin calcium excellent in stability, is presented. In the production of a compound (pitavastatin calcium) represented by the formula (1): The water content is adjusted to a level of from 5 to 15%, and the crystal form is controlled to be crystal form A, thereby to obtain a drug substance excellent in stability.
    Type: Application
    Filed: June 14, 2023
    Publication date: October 12, 2023
    Applicant: NISSAN CHEMICAL CORPORATION
    Inventors: Yoshio OHARA, Yasutaka TAKADA, Hiroo MATSUMOTO, Akihiro YOSHIDA
  • Publication number: 20220177433
    Abstract: A method for producing a drug substance of crystalline pitavastatin calcium excellent in stability, is presented. In the production of a compound (pitavastatin calcium) represented by the formula (1): The water content is adjusted to a level of from 5 to 15%, and the crystal form is controlled to be crystal form A, thereby to obtain a drug substance excellent in stability.
    Type: Application
    Filed: February 28, 2022
    Publication date: June 9, 2022
    Applicant: NISSAN CHEMICAL CORPORATION
    Inventors: Yoshio OHARA, Yasutaka TAKADA, Hiroo MATSUMOTO, Akihiro YOSHIDA
  • Publication number: 20210053923
    Abstract: A method for producing a drug substance of crystalline pitavastatin calcium excellent in stability, is presented. In the production of a compound (pitavastatin calcium) represented by the formula (1): The water content is adjusted to a level of from 5 to 15%, and the crystal form is controlled to be crystal form A, thereby to obtain a drug substance excellent in stability.
    Type: Application
    Filed: November 5, 2020
    Publication date: February 25, 2021
    Applicant: NISSAN CHEMICAL CORPORATION
    Inventors: Yoshio OHARA, Yasutaka Takada, Hiroo Matsumoto, Akihiro Yoshida
  • Publication number: 20200216395
    Abstract: A method for producing a drug substance of crystalline pitavastatin calcium excellent in stability, is presented. In the production of a compound (pitavastatin calcium) represented by the formula (1): The water content is adjusted to a level of from 5 to 15%, and the crystal form is controlled to be crystal form A, thereby to obtain a drug substance excellent in stability.
    Type: Application
    Filed: March 16, 2020
    Publication date: July 9, 2020
    Applicant: NISSAN CHEMICAL CORPORATION
    Inventors: Yoshio Ohara, Yasutaka Takada, Hiroo Matsumoto, Akihiro Yoshida
  • Publication number: 20190367458
    Abstract: A method for producing a drug substance of crystalline pitavastatin calcium excellent in stability, is presented. In the production of a compound (pitavastatin calcium) represented by the formula (1): The water content is adjusted to a level of from 5 to 15%, and the crystal folio is controlled to be crystal form A, thereby to obtain a drug substance excellent in stability.
    Type: Application
    Filed: August 19, 2019
    Publication date: December 5, 2019
    Applicant: NISSAN CHEMICAL CORPORATION
    Inventors: Yoshio Ohara, Yasutaka Takada, Hiroo Matsumoto, Akihiro Yoshida
  • Publication number: 20190152916
    Abstract: A method for producing a drug substance of crystalline pitavastatin calcium excellent in stability, is presented, In the production of a compound (pitavastatin calcium) represented by the formula (1): The water content is adjusted to a level of from 5 to 15%, and the crystal form is controlled to be crystal form A, thereby to obtain a drug substance excellent in stability.
    Type: Application
    Filed: January 24, 2019
    Publication date: May 23, 2019
    Applicant: NISSAN CHEMICAL CORPORATION
    Inventors: Yoshio OHARA, Yasutaka Takada, Hiroo Matsumoto, Akihiro Yoshida
  • Publication number: 20180297956
    Abstract: A method for producing a drug substance of crystalline pitavastatin calcium excellent in stability, is presented. In the production of a compound (pitavastatin calcium) represented by the formula (1): The water content is adjusted to a level of from 5 to 15%, and the crystal form is controlled to be crystal form A, thereby to obtain a drug substance excellent in stability.
    Type: Application
    Filed: June 19, 2018
    Publication date: October 18, 2018
    Applicant: NISSAN CHEMICAL INDUSTRIES, LTD.
    Inventors: Yoshio OHARA, Yasutaka TAKADA, Hiroo MATSUMOTO, Akihiro YOSHIDA
  • Publication number: 20180072676
    Abstract: A method for producing a drug substance of crystalline pitavastatin calcium excellent in stability, is presented. In the production of a compound (pitavastatin calcium) represented by the formula (1): The water content is adjusted to a level of from 5 to 15%, and the crystal form is controlled to be crystal form A, thereby to obtain a drug substance excellent in stability.
    Type: Application
    Filed: November 15, 2017
    Publication date: March 15, 2018
    Applicant: NISSAN CHEMICAL INDUSTRIES, LTD.
    Inventors: Yoshio OHARA, Yasutaka TAKADA, Hiroo MATSUMOTO, Akihiro YOSHIDA
  • Patent number: 9776251
    Abstract: A cutting insert is configured to include: a first portion having a rake face, a flank face, a cutting edge, and a face facing an insert attachment portion at an end of a tool main body; and a second portion having a side surface including at least one flat plane that is parallel to a center line of a tool or inclined at a prescribed angle to the center line. The second portion extends continuously to a region surrounded by the face of the first portion. The second portion is fitted into the tool main body to position the cutting insert and to prevent the cutting insert from rotating.
    Type: Grant
    Filed: August 6, 2013
    Date of Patent: October 3, 2017
    Assignees: Sumitomo Electric Hardmetal Corp., Sumitomo Electric Industries, Ltd., DMG MORI SEIKI CO., LTD.
    Inventors: Junya Okida, Kazuya Ishikawa, Shigenori Emoto, Daisuke Murakami, Shinya Ikenaga, Kazuo Noguchi, Suehiro Ikeda, Takayuki Hirokawa, Yoshio Ohara, Morihiro Hideta, Yohei Oda
  • Publication number: 20170226061
    Abstract: A method for producing a drug substance of crystalline pitavastatin calcium excellent in stability, is presented. In the production of a compound (pitavastatin calcium) represented by the formula (1): The water content is adjusted to a level of from 5 to 15%, and the crystal form is controlled to be crystal form A, thereby to obtain a drug substance excellent in stability.
    Type: Application
    Filed: September 15, 2016
    Publication date: August 10, 2017
    Applicant: NISSAN CHEMICAL INDUSTRIES, LTD.
    Inventors: Yoshio OHARA, Yasutaka Takada, Hiroo Matsumoto, Akihiro Yoshida
  • Publication number: 20150231702
    Abstract: A cutting insert is configured to include: a first portion having a rake face, a flank face, a cutting edge, and a face facing an insert attachment portion at an end of a tool main body; and a second portion having a side surface including at least one flat plane that is parallel to a center line of a tool or inclined at a prescribed angle to the center line. The second portion extends continuously to a region surrounded by the face of the first portion. The second portion is fitted into the tool main body to position the cutting insert and to prevent the cutting insert from rotating.
    Type: Application
    Filed: August 6, 2013
    Publication date: August 20, 2015
    Inventors: Junya Okida, Kazuya Ishikawa, Shigenori Emoto, Daisuke Murakami, Shinya Ikenaga, Kazuo Noguchi, Suehiro Ikeda, Takayuki Hirokawa, Yoshio Ohara, Morihiro Hideta, Yohei Oda
  • Publication number: 20150158816
    Abstract: A method for producing a drug substance of crystalline pitavastatin calcium excellent in stability, is presented. In the production of a compound (pitavastatin calcium) represented by the formula (1): The water content is adjusted to a level of from 5 to 15%, and the crystal form is controlled to be crystal form A, thereby to obtain a drug substance excellent in stability.
    Type: Application
    Filed: February 18, 2015
    Publication date: June 11, 2015
    Applicant: NISSAN CHEMICAL INDUSTRIES, LTD.
    Inventors: Yoshio OHARA, Yasutaka TAKADA, Hiroo MATSUMOTO, Akihiro YOSHIDA
  • Publication number: 20140206719
    Abstract: A method for producing a drug substance of crystalline pitavastatin calcium excellent in stability, is presented. In the production of a compound (pitavastatin calcium) represented by the formula (1): The water content is adjusted to a level of from 5 to 15%, and the crystal form is controlled to be crystal form A, thereby to obtain a drug substance excellent in stability.
    Type: Application
    Filed: March 21, 2014
    Publication date: July 24, 2014
    Applicant: NISSAN CHEMICAL INDUSTRIES, LTD.
    Inventors: Yoshio OHARA, Yasutaka TAKADA, Hiroo MATSUMOTO, Akihiro YOSHIDA
  • Publication number: 20140058109
    Abstract: A method for producing a drug substance of crystalline pitavastatin calcium excellent in stability, is presented. In the production of a compound (pitavastatin calcium) represented by the formula (1): The water content is adjusted to a level of from 5 to 15%, and the crystal form is controlled to be crystal form A, thereby to obtain a drug substance excellent in stability.
    Type: Application
    Filed: October 30, 2013
    Publication date: February 27, 2014
    Applicant: NISSAN CHEMICAL INDUSTRIES, LTD.
    Inventors: Yoshio OHARA, Yasutaka Takada, Hiroo Matsumoto, Akihiro Yoshida
  • Publication number: 20120245200
    Abstract: A method for producing a drug substance of crystalline pitavastatin calcium excellent in stability, is presented. In the production of a compound (pitavastatin calcium) represented by the formula (1): The water content is adjusted to a level of from 5 to 15%, and the crystal form is controlled to be crystal form A, thereby to obtain a drug substance excellent in stability.
    Type: Application
    Filed: June 4, 2012
    Publication date: September 27, 2012
    Applicant: NISSAN CHEMICAL INDUSTRIES, LTD.
    Inventors: Yoshio OHARA, Yasutaka Takada, Hiroo Matsumoto, Akihiro Yoshida
  • Publication number: 20110319624
    Abstract: A method for producing a drug substance of crystalline pitavastatin calcium excellent in stability, is presented. In the production of a compound (pitavastatin calcium) represented by the formula (1): The water content is adjusted to a level of from 5 to 15%, and the crystal form is controlled to be crystal form A, thereby to obtain a drug substance excellent in stability.
    Type: Application
    Filed: September 7, 2011
    Publication date: December 29, 2011
    Applicant: Nissan Chemical Industries, Ltd.
    Inventors: Yoshio Ohara, Yasutaka Takada, Hiroo Matsumoto, Akihiro Yoshida
  • Publication number: 20110082298
    Abstract: A method for producing a drug substance of crystalline pitavastatin calcium excellent in stability, is presented. In the production of a compound (pitavastatin calcium) represented by the formula (1): The water content is adjusted to a level of from 5 to 15%, and the crystal form is controlled to be crystal form A, thereby to obtain a drug substance excellent in stability.
    Type: Application
    Filed: December 13, 2010
    Publication date: April 7, 2011
    Applicant: Nissan Chemical Industries, Ltd.
    Inventors: Yoshio OHARA, Yasutaka TAKADA, Hiroo MATSUMOTO, Akihiro YOSHIDA
  • Publication number: 20100003373
    Abstract: It is an objective of the present invention to provide a means for producing rapidly soluble granules with the use of any powdery raw material that is poorly sedimented in water and thus is dispersed or dissolved with difficulty in water. According to the present invention, a method for producing rapidly soluble granules, comprising mixing granules having poor sedimentation property in water and granules having good sedimentation property in water while adding an emulsifier thereto to thereby obtain mixed granules coated with the emulsifier.
    Type: Application
    Filed: April 3, 2006
    Publication date: January 7, 2010
    Applicant: MEIJI SEIKA KAISHA, LTD.
    Inventors: Yoshio Ohara, Akio Tanaka, Tetsuya Magarikaji
  • Publication number: 20090176987
    Abstract: A method for producing a drug substance of crystalline pitavastatin calcium excellent in stability, is presented. In the production of a compound (pitavastatin calcium) represented by the formula (1): The water content is adjusted to a level of from 5 to 15%, and the crystal form is controlled to be crystal form A, thereby to obtain a drug substance excellent in stability.
    Type: Application
    Filed: March 11, 2009
    Publication date: July 9, 2009
    Applicant: Nissan Chemical Industries, Ltd.
    Inventors: Yoshio OHARA, Yasutaka TAKADA, Hiroo MATSUMOTO, Akihiro YOSHIDA
  • Publication number: 20070112024
    Abstract: A method for producing a drug substance of crystalline pitavastatin calcium excellent in stability, is presented. In the production of a compound (pitavastatin calcium) represented by the formula (1): The water content is adjusted to a level of from 5 to 15%, and the crystal form is controlled to be crystal form A, thereby to obtain a drug substance excellent in stability.
    Type: Application
    Filed: December 17, 2004
    Publication date: May 17, 2007
    Inventors: Yoshio Ohara, Yasutaka Takada, Hiroo Matsumoto, Akihiro Yoshida