Patents by Inventor Yoshio Shimizu
Yoshio Shimizu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240037056Abstract: A host (100) includes a PCIe Root Complex (102), a PCIe Expander (116) configured to be connected to a general-purpose network N, and a PCIe switch (108) including PCIe ports and configured to switch a connection between the Root Complex (102) and the Expander (116), in which the Expander (116) enables PCIe ports (109, 113) connected to upstream ports of the Root Complex (102) and the Expander (116) and disables a PCIe port (110) connected to a downstream port of the Expander (116) when the host (100) functions as a master, and disables the upstream port (109) and the downstream port (113) and enables the upstream port (110) when the host 100 functions as a slave.Type: ApplicationFiled: July 16, 2021Publication date: February 1, 2024Applicant: NEC CorporationInventor: Yoshio SHIMIZU
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Patent number: 10252972Abstract: A method of chemically extending a carbon chain of an unsaturated fatty acid for conversion into a different unsaturated fatty acid has been reported. The present invention shortens reaction steps of conventional methods, and completes a carbon chain extending reaction in a shorter time. The present invention provides a method of extending a carbon chain of an unsaturated fatty acid by two carbons, comprising steps of four stages including a short-path conversion reaction of an unsaturated fatty chain obtained from an unsaturated fatty acid into a malonic ester derivative, and heating of the malonic ester derivative to reflux in a lower fatty acid solution. The method of the present invention can complete a carbon chain extending reaction in a shorter time.Type: GrantFiled: June 27, 2016Date of Patent: April 9, 2019Assignee: Bizen Chemical Co., Ltd.Inventors: Naomichi Bamba, Yoshihisa Misawa, Hiroshi Tabata, Yoshio Shimizu
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Patent number: 10240172Abstract: The present invention relates to the field of methods for purifying fatty acid ethyl esters. According to the present invention, a method for obtaining a ?3 fatty acid ethyl ester, such as EPA and DHA, each as a high purity product at a high yield is provided. In the method according to the present invention, a raw material fat including EPA and DHA is treated with a lipolytic enzyme and ethyl-esterification is performed as needed; the treated substance is fractionated into a glyceride fraction and a free fatty acid fraction; a fraction comprising more EPA ester and a fraction comprising DHA ester are obtained from the respective fractions; the fraction comprising more EPA ester is purified to prepare a high-purity EPA ester; and the fraction comprising more DHA ester is purified to prepare a high-purity DHA ester.Type: GrantFiled: August 18, 2014Date of Patent: March 26, 2019Assignee: Bizen Chemical Co., Ltd.Inventors: Yoshio Shimizu, Keisuke Uryu, Tetsuro Taira, Jun Fujii
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Patent number: 10196584Abstract: A production method of highly unsaturated fatty acids with a high purity/high yield that compensates for shortcomings of conventional techniques is provided. A purification method of highly unsaturated fatty acids and/or derivatives thereof comprising (a) contacting and stirring first raw materials comprising the substances with a first silver salt aqueous solution to collect a first oil layer and a first aqueous layer; (b) separating the first aqueous layer into a second silver salt aqueous solution and the substances; and (c) contacting and stirring the first oil layer with the second silver salt aqueous solution for separation into an oil layer and an aqueous layer to obtain a second aqueous layer comprising the substances.Type: GrantFiled: May 30, 2016Date of Patent: February 5, 2019Assignee: Bizen Chemical Co., Ltd.Inventors: Hiroshi Tabata, Tetsuro Taira, Jun Fujii, Yoshihisa Misawa, Yoshio Shimizu
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Patent number: 10189770Abstract: The present invention provides a method of producing/purifying highly unsaturated fatty acids and/or derivatives thereof while suppressing deterioration of a silver salt aqueous solution, in production/purification of highly unsaturated fatty acids and/or derivatives thereof using the aqueous solution of silver salt. The present invention also contacts or mixes a mixture having a peroxide value (POV) of 10 or smaller with an aqueous solution of silver salt, in a method of purifying highly unsaturated fatty acids and/or derivatives thereof from a mixture comprising highly unsaturated fatty acids and/or derivatives thereof.Type: GrantFiled: May 30, 2016Date of Patent: January 29, 2019Assignee: Bizen Chemical Co., Ltd.Inventors: Mitsumasa Mankura, Yoshihisa Misawa, Yoshio Shimizu
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Publication number: 20180186720Abstract: A method of chemically extending a carbon chain of an unsaturated fatty acid for conversion into a different unsaturated fatty acid has been reported. The present invention shortens reaction steps of conventional methods, and completes a carbon chain extending reaction in a shorter time. The present invention provides a method of extending a carbon chain of an unsaturated fatty acid by two carbons, comprising steps of four stages including a short-path conversion reaction of an unsaturated fatty chain obtained from an unsaturated fatty acid into a malonic ester derivative, and heating of the malonic ester derivative to reflux in a lower fatty acid solution. The method of the present invention can complete a carbon chain extending reaction in a shorter time.Type: ApplicationFiled: June 27, 2016Publication date: July 5, 2018Inventors: Naomichi BAMBA, Yoshihisa MISAWA, Hiroshi TABATA, Yoshio SHIMIZU
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Patent number: 10005712Abstract: The present invention relates to a method for the chemical conversion of an unsaturated fatty acid, particularly a carbon chain extension reaction. According to the present invention, a method for extending the length of a carbon chain in an unsaturated fatty acid by two carbon atoms is provided, said method comprising a step of heating a malonic acid ester derivative of an unsaturated fatty acid to reflux in a lower fatty acid solution in the presence of an antioxidative agent. It is preferred that the unsaturated fatty acid is an unsaturated fatty acid having 16 to 24 carbon atoms. It is preferred that the unsaturated fatty acid is selected from the group consisting of linoleic acid, linolenic acid, arachidonic acid, stearidonic acid, icosatetraenoic acid, icosapentaenoic acid, tetracosahexaenoic acid and docosahexaenoic acid. According to the method of the present invention, a carbon chain extension reaction can be completed within a shorter time.Type: GrantFiled: January 14, 2015Date of Patent: June 26, 2018Assignee: BIZEN CHEMICAL CO., LTD.Inventors: Yoshio Shimizu, Naomichi Bamba, Mitsumasa Mankura
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Publication number: 20180155268Abstract: The present invention provides a method of producing/purifying highly unsaturated fatty acids and/or derivatives thereof while suppressing deterioration of a silver salt aqueous solution, in production/purification of highly unsaturated fatty acids and/or derivatives thereof using the aqueous solution of silver salt. The present invention also contacts or mixes a mixture having a peroxide value (POV) of 10 or smaller with an aqueous solution of silver salt, in a method of purifying highly unsaturated fatty acids and/or derivatives thereof from a mixture comprising highly unsaturated fatty acids and/or derivatives thereof.Type: ApplicationFiled: May 30, 2016Publication date: June 7, 2018Inventors: Mitsumasa Mankura, Yoshihisa Misawa, Yoshio Shimizu
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Publication number: 20180148664Abstract: A production method of highly unsaturated fatty acids with a high purity/high yield that compensates for shortcomings of conventional techniques is provided. A purification method of highly unsaturated fatty acids and/or derivatives thereof comprising (a) contacting and stirring first raw materials comprising the substances with a first silver salt aqueous solution to collect a first oil layer and a first aqueous layer; (b) separating the first aqueous layer into a second silver salt aqueous solution and the substances; and (c) contacting and stirring the first oil layer with the second silver salt aqueous solution for separation into an oil layer and an aqueous layer to obtain a second aqueous layer comprising the substances.Type: ApplicationFiled: May 30, 2016Publication date: May 31, 2018Inventors: Hiroshi Tabata, Tetsuro Taira, Jun Fujii, Yoshihisa Misawa, Yoshio Shimizu
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Publication number: 20170166512Abstract: The present invention relates to a method for the chemical conversion of an unsaturated fatty acid, particularly a carbon chain extension reaction. According to the present invention, a method for extending the length of a carbon chain in an unsaturated fatty acid by two carbon atoms is provided, said method comprising a step of heating a malonic acid ester derivative of an unsaturated fatty acid to reflux in a lower fatty acid solution in the presence of an antioxidative agent. It is preferred that the unsaturated fatty acid is an unsaturated fatty acid having 16 to 24 carbon atoms. It is preferred that the unsaturated fatty acid is selected from the group consisting of linoleic acid, linolenic acid, arachidonic acid, stearidonic acid, icosatetraenoic acid, icosapentaenoic acid, tetracosahexaenoic acid and docosahexaenoic acid. According to the method of the present invention, a carbon chain extension reaction can be completed within a shorter time.Type: ApplicationFiled: January 14, 2015Publication date: June 15, 2017Applicant: Bizen Chemical Co., Ltd.Inventors: Yoshio Shimizu, Naomichi Bamba, Mitsumasa Mankura
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Publication number: 20160361285Abstract: The present invention relates to a method for producing and purifying SDA at high purity and/or high yield from a raw material such as anchovy oil. According to the present invention, when separating and purifying SDA from a raw material (e.g. anchovy oil) that includes SDA, high-quality, high-purity SDA is produced at a high recovery rate by using a combination of ethyl esterification and a silver nitrate treatment method. (1) A purification method selected from the group consisting of a thin-film vacuum superfractionation method, a simulated moving bed chromatography method, a urea addition method, and a molecular distillation method, and (2) an adsorbent treatment may be combined, as necessary.Type: ApplicationFiled: February 13, 2015Publication date: December 15, 2016Inventors: Tadahiro Tsusima, Yoshio Shimizu
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Publication number: 20160208296Abstract: The present invention relates to the field of methods for purifying fatty acid ethyl esters. According to the present invention, a method for obtaining a ?3 fatty acid ethyl ester, such as EPA and DHA, each as a high purity product at a high yield is provided. In the method according to the present invention, a raw material fat including EPA and DHA is treated with a lipolytic enzyme and ethyl-esterification is performed as needed; the treated substance is fractionated into a glyceride fraction and a free fatty acid fraction; a fraction comprising more EPA ester and a fraction comprising DHA ester are obtained from the respective fractions; the fraction comprising more EPA ester is purified to prepare a high-purity EPA ester; and the fraction comprising more DHA ester is purified to prepare a high-purity DHA ester.Type: ApplicationFiled: August 18, 2014Publication date: July 21, 2016Applicant: Bizen Chemical Co., Ltd.Inventors: Yoshio SHIMIZU, Keisuke URYU, Tetsuro TAIRA, Jun FUJII
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Publication number: 20160193546Abstract: The present invention provides a separation method and device, comprising columns with at least two types of gels selected from the group consisting of silica gel, silver nitrate-impregnated gel and polymer gel filled therein, preferably at least three silver nitrate-impregnated gel columns and at least one silica gel column, by SMB chromatography. The present invention also provides a separation method and device, comprising columns with at least two types of columns selected from the group consisting of C18 columns, C8 columns C4 columns and C1 columns, preferably at least three C18 columns and at least one C8 column and/or C4 column and/or C1 column, by SMB chromatography.Type: ApplicationFiled: July 7, 2014Publication date: July 7, 2016Inventors: Yoshio Shimizu, Hiroshi Tabata, Mitsumasa Mankura
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Patent number: 9022947Abstract: Continuous measurement of breathing impedance with extremely high precision is enabled by executing noise elimination. A loudspeaker applies an air vibration pressure by an oscillation wave to an oral cavity, the oscillation wave being obtained by frequency-cuffing so executed that the oscillation wave has only the frequency component that is left after the culling is executed from a plurality of different frequencies and being generated by a pulse signal for pulse drive with pulses made positive and negative separately in correspondence to the time of exhalation and the time of inhalation. A pressure inside the oral cavity is detected and a breathing flow is detected, and a signal obtained by the detection is Fourier-transformed to obtain a spectrum. Analysis of the spectrum is performed to obtain breathing impedance.Type: GrantFiled: April 12, 2010Date of Patent: May 5, 2015Assignees: Chest M.I. Incorporated, Tohoku Techno Arch Co., Ltd.Inventors: Hajime Kurosawa, Yoshio Shimizu, Toshiaki Hoki
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Patent number: 8680305Abstract: A method of obtaining a polyunsaturated fatty acid derivative comprises contacting a mixture of fatty acid derivatives with a silver salt aqueous solution, and adjusting the free fatty acid content in the silver salt aqueous solution to 0.2 meq or less per gram of silver when repeatedly using the silver salt aqueous solution. A polyunsaturated fatty acid derivative having high purity and excellent quality can thus be economically obtained.Type: GrantFiled: September 2, 2009Date of Patent: March 25, 2014Assignees: Q.P. Corporation, Bizen Chemical Co., Ltd.Inventors: Hiroyuki Sakaguchi, Hideaki Kobayashi, Yoshihisa Misawa, Keisuke Uryu, Yoshio Shimizu
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Publication number: 20130165514Abstract: The present invention provides an orally administered composition and a dietary composition, which have a serum lipid improving effect. The orally administered composition and dietary composition, having a serum lipid improving effect, according to the present invention camp rise 2.0% by weight or less of a DHA ethyl ester composition comprising 75% by weight or more of DHA ethyl ester. It is preferable to comprise 1.2% by weight or less of the DHA ethyl ester composition. It is preferable not to substantially comprise a DHA ethyl ester composition comprising 30% by weight or less of DHA ethyl ester.Type: ApplicationFiled: February 18, 2011Publication date: June 27, 2013Applicant: BIZEN CHEMICAL CO., LTD.Inventors: Kenji Fukunaga, Yoshio Shimizu, Mikiya Takamoto, Teruyuki Kanada
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Publication number: 20120101400Abstract: Continuous measurement of breathing impedance with extremely high precision is enabled by executing noise elimination. A loudspeaker 21 applies an air vibration pressure by an oscillation wave to an oral cavity, the oscillation wave being obtained by frequency-culling so executed that the oscillation wave has only the frequency component that is left after the culling is executed from a plurality of different frequencies and being generated by a pulse signal for pulse drive with pulses made positive and negative separately in correspondence to the time of exhalation and the time of inhalation. A pressure inside the oral cavity is detected and a breathing flow is detected, and a signal obtained by the detection is Fourier-transformed by a Fourier transforming means 32 to obtain a spectrum. A breathing high frequency component that contributes as a noise is obtained by an extracting means 33, using a spectrum that corresponds to a frequency component culled from the result of the Fourier transformation.Type: ApplicationFiled: April 12, 2010Publication date: April 26, 2012Applicants: THOKU TECHNO ARCH CO., LTD., CHEST M.I., INCORPORATEDInventors: Hajime Kurosawa, Yoshio Shimizu, Toshiaki Hoki
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Publication number: 20110224452Abstract: A method of obtaining a polyunsaturated fatty acid derivative comprises contacting a mixture of fatty acid derivatives with a silver salt aqueous solution, and adjusting the free fatty acid content in the silver salt aqueous solution to 0.2 meq or less per gram of silver when repeatedly using the silver salt aqueous solution. A polyunsaturated fatty acid derivative having high purity and excellent quality can thus be economically obtained.Type: ApplicationFiled: September 2, 2009Publication date: September 15, 2011Applicants: Q.P. CORPORATION, BIZEN CHEMICAL CO., LTD.Inventors: Hiroyuki Sakaguchi, Hideaki Kobayashi, Yoshihisa Misawa, Keisuke Uryu, Yoshio Shimizu
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Patent number: 7913627Abstract: An upper and lower path switching device for a traveling body for transportation has an elevating guide rail supported horizontally by an elevating body, upper fixed guide rails which are connected to the elevating guide rail at a lifted position of the elevating body, and lower fixed guide rails which are connected to the elevating guide rail at a lowered position of the elevating body. The elevating guide rail is supported movably vertically in a predetermined range with respect to the elevating body. Receiving members are provided for receiving the elevating guide rail at a level at which the elevating guide rail is connected to the lower fixed guide rails before the elevating body reaches a lower limit of an elevation path of the elevating body.Type: GrantFiled: January 18, 2008Date of Patent: March 29, 2011Assignee: Daifuku Co. Ltd.Inventors: Yoshio Shimizu, Teruaki Nabeta
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Publication number: 20110060237Abstract: Continuous measurement of respiratory impedance with very high precision is enabled by executing noise removal. An air vibration pressure by an oscillation wave obtained by frequency culling such that the oscillation wave has only frequency components left by the culling from a plurality of different frequencies, is applied by a loudspeaker 21 to the inside of an oral cavity. The pressure in the oral cavity is detected and the flow of breathing is detected. These signals obtained are Fourier-transformed by a Fourier transforming means 32 and, thereby, a spectrum is obtained. A breathing high frequency component that contributes as a noise is obtained by the extracting means 33 using a spectrum that corresponds to the frequency components culled from the result of the Fourier transformation. The breathing high frequency component is subtracted from the spectrum that corresponds to the frequency components left by the culling and, thereby, the oscillation wave component is extracted.Type: ApplicationFiled: March 9, 2009Publication date: March 10, 2011Inventors: Hajime Kurosawa, Yoshio Shimizu, Toshiaki Hoki