Patents by Inventor Yoshio Takatori
Yoshio Takatori has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9216241Abstract: An object is to provide a medical device having excellent antithrombotic and sliding characteristics, which can exert a cell adhesion inhibitory effect. A medical device comprising: a substrate capable of forming hydroxyl groups; and a biocompatible material layer laminated on the substrate at an appropriate position, wherein the hydroxyl groups are formed on a surface of the substrate at least at a required position by a surface treatment, while the biocompatible material layer is formed from a polymer containing phosphorylcholine groups, and wherein the substrate and the biocompatible material layer are joined via a binder layer formed from silica being covalently bonded with the hydroxyl groups and the biocompatible material, respectively.Type: GrantFiled: December 19, 2008Date of Patent: December 22, 2015Assignees: KYOCERA MEDICAL CORPORATION, THE UNIVERSITY OF TOKYOInventors: Masayuki Kyomoto, Kazuhiko Ishihara, Kozo Nakamura, Yoshio Takatori, Hiroshi Kawaguchi, Toru Moro
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Patent number: 9192694Abstract: The object of the present invention is to provide a sliding member, a prosthesis and a method of producing the sliding member, which can suppress production of abrasive wear debris by suppressing friction of the sliding section, and also can maintain satisfactory mechanical characteristics in vivo. A sliding member comprising: a substrate 1 capable of forming hydroxyl groups; and a biocompatible material layer 4 laminated on appropriate sections of the substrate 1, wherein hydroxyl groups are formed on at least a required section of a surface of the substrate 1 by surface treating to form a surface-treated layer 2, while the biocompatible material layer 4 is formed from a polymer containing phosphorylcholine groups, and wherein the substrate 1 and the biocompatible material layer 4 are joined via a binder layer 3 formed from silica being covalently bonded with the hydroxyl groups and the biocompatible material, respectively.Type: GrantFiled: October 2, 2008Date of Patent: November 24, 2015Assignees: KYOCERA MEDICAL CORPORATION, THE UNIVERSITY OF TOKYOInventors: Masayuki Kyomoto, Kazuhiko Ishihara, Kozo Nakamura, Yoshio Takatori, Hiroshi Kawaguchi, Toru Moro
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Patent number: 9044323Abstract: The present invention provides a bearing material that is excellent in durability and is capable of maintaining wear resistance over a long period of time. The bearing material of the present invention is a high wear-resistance bearing material 10 for being used under a humid environment comprising: a base body 12 made of a polymer material having a methylene group; and a polymer layer 30 covering a bearing surface 16 of the substrate 12, the polymer layer 30 comprising polymer chains which have a phosphorylcholine group and are grafted from the bearing surface 16, wherein a phosphoric index of the sliding surface 16 which is calculated by dividing a peak intensity of phosphate group in an infrared spectrum measured on the sliding surface by a peak intensity of the methylene group therein is not less than 0.28.Type: GrantFiled: February 5, 2007Date of Patent: June 2, 2015Assignee: KYOCERA MEDICAL CORPORATIONInventors: Masayuki Kyomoto, Toru Moro, Kazuhiko Ishihara, Tomohiro Konno, Kozo Nakamura, Yoshio Takatori, Hiroshi Kawaguchi, Hiroaki Takadama, Makoto Kondo, Noboru Yamawaki, Takeshi Nizuka, Masami Hashimoto
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Patent number: 9034414Abstract: The object of the present invention is to provide a joint prosthesis, bearing material and a production method thereof, which suppresses wear in a sliding section and suppresses the production of abrasive powder even during repeated daily operation. To achieve the object, there is provided a biomaterial comprising: a substrate made of metal, alloy or ceramic; and a biocompatible material layer laminated on the substrate, wherein hydroxyl groups are formed on the substrate by surface-treating, while the biocompatible material layer comprises a polymer containing phosphorylcholine groups, the substrate and the biocompatible material layer are bound via a binder layer which is combined with the hydroxyl groups of the substrate and with the biocompatible material layer.Type: GrantFiled: February 21, 2014Date of Patent: May 19, 2015Assignees: KYOCERA MEDICAL CORPORATION, THE UNIVERSITY OF TOKYO, NATIONAL UNIVERSITY CORPORATION TOKYO MEDICAL AND DENTAL UNIVERSITYInventors: Masayuki Kyomoto, Kazuhiko Ishihara, Yasuhiko Iwasaki, Toru Moro, Kozo Nakamura, Yoshio Takatori, Hiroshi Kawaguchi, Tomohiro Konno, Noboru Yamawaki
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Publication number: 20140170331Abstract: The object of the present invention is to provide a joint prosthesis, bearing material and a production method thereof, which suppresses wear in a sliding section and suppresses the production of abrasive powder even during repeated daily operation. To achieve the object, there is provided a biomaterial comprising: a substrate made of metal, alloy or ceramic; and a biocompatible material layer laminated on the substrate, wherein hydroxyl groups are formed on the substrate by surface-treating, while the biocompatible material layer comprises a polymer containing phosphorylcholine groups, the substrate and the biocompatible material layer are bound via a binder layer which is combined with the hydroxyl groups of the substrate and with the biocompatible material layer.Type: ApplicationFiled: February 21, 2014Publication date: June 19, 2014Applicants: KYOCERA Medical Corporation, NATIONAL UNIVERSITY CORPORATION TOKYO MEDICAL AND DENTAL UNIVERSITY, THE UNIVERSITY OF TOKYOInventors: Masayuki KYOMOTO, Kazuhiko ISHIHARA, Yasuhiko IWASAKI, Toru MORO, Kozo NAKAMURA, Yoshio TAKATORI, Hiroshi KAWAGUCHI, Tomohiro KONNO, Noboru YAMAWAKI
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Patent number: 8697238Abstract: The object of the present invention is to provide a joint prosthesis, bearing material and a production method thereof, which suppresses wear in a sliding section and suppresses the production of abrasive powder even during repeated daily operation. To achieve the object, there is provided a biomaterial comprising: a substrate made of metal, alloy or ceramic; and a biocompatible material layer laminated on the substrate, wherein hydroxyl groups are formed on the substrate by surface-treating, while the biocompatible material layer comprises a polymer containing phosphorylcholine groups, the substrate and the biocompatible material layer are bound via a binder layer which is combined with the hydroxyl groups of the substrate and with the biocompatible material layer.Type: GrantFiled: March 26, 2007Date of Patent: April 15, 2014Assignees: Kyocera Medical Corporation, The University of Tokyo, National University Corporation Tokyo Medical and Dental UniversityInventors: Masayuki Kyomoto, Kazuhiko Ishihara, Yasuhiko Iwasaki, Toru Moro, Kozo Nakamura, Yoshio Takatori, Hiroshi Kawaguchi, Tomohiro Konno, Noboru Yamawaki
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Publication number: 20120197413Abstract: The object of the present invention is to provide a sliding member, a prosthesis and a method of producing the sliding member, which can suppress production of abrasive wear debris by suppressing friction of the sliding section, and also can maintain satisfactory mechanical characteristics in vivo. A sliding member comprising: a substrate 1 capable of forming hydroxyl groups; and a biocompatible material layer 4 laminated on appropriate sections of the substrate 1, wherein hydroxyl groups are formed on at least a required section of a surface of the substrate 1 by surface treating to form a surface-treated layer 2, while the biocompatible material layer 4 is formed from a polymer containing phosphorylcholine groups, and wherein the substrate 1 and the biocompatible material layer 4 are joined via a binder layer 3 formed from silica being covalently bonded with the hydroxyl groups and the biocompatible material, respectively.Type: ApplicationFiled: October 2, 2008Publication date: August 2, 2012Inventors: Masayuki Kyomoto, Kazuhiko Ishihara, Kozo Nakamura, Yoshio Takatori, Hiroshi Kawaguchi, Toru Moro
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Publication number: 20110027757Abstract: An object is to provide a medical device having excellent antithrombotic and sliding characteristics, which can exert a cell adhesion inhibitory effect. A medical device comprising: a substrate capable of forming hydroxyl groups; and a biocompatible material layer laminated on the substrate at an appropriate position, wherein the hydroxyl groups are formed on a surface of the substrate at least at a required position by a surface treatment, while the biocompatible material layer is formed from a polymer containing phosphorylcholine groups, and wherein the substrate and the biocompatible material layer are joined via a binder layer formed from silica being covalently bonded with the hydroxyl groups and the biocompatible material, respectively.Type: ApplicationFiled: December 19, 2008Publication date: February 3, 2011Inventors: Masayuki Kyomoto, Kazuhiko Ishihara, Kozo Nakamura, Yoshio Takatori, Hiroshi Kawaguchi, Toru Moro
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Publication number: 20100262237Abstract: The object of the present invention is to provide a joint prosthesis, bearing material and a production method thereof, which suppresses wear in a sliding section and suppresses the production of abrasive powder even during repeated daily operation. To achieve the object, there is provided a biomaterial comprising: a substrate made of metal, alloy or ceramic; and a biocompatible material layer laminated on the substrate, wherein hydroxyl groups are formed on the substrate by surface-treating, while the biocompatible material layer comprises a polymer containing phosphorylcholine groups, the substrate and the biocompatible material layer are bound via a binder layer which is combined with the hydroxyl groups of the substrate and with the biocompatible material layer.Type: ApplicationFiled: March 26, 2007Publication date: October 14, 2010Applicants: JAPAN MEDICAL MATERIALS CORPORATION, THE UNIVERSITY OF TOKYO, NATIONAL UNIVERSITY CORPORATION TOKYO MEDICAL AND DENTAL UNIVERSITYInventors: Masayuki Kyomoto, Kazuhiko Ishihara, Yasuhiko Iwasaki, Toru Moro, Kozo Nakamura, Yoshio Takatori, Hiroshi Kawaguchi, Tomohiro Konno, Noboru Yamawaki
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Patent number: 7785372Abstract: An artificial joint member made of a polymeric material including a portion made of a polymeric substance has a sliding surface composed of a polymer having phosphoryl choline groups. With such an arrangement, the artificial joint member is provided with a sliding part capable of keeping a satisfactory lubricating state for a long time.Type: GrantFiled: February 19, 2003Date of Patent: August 31, 2010Assignees: Kabushiki Kaisha Kobe Seiko ShoInventors: Kazuhiko Ishihara, Toru Moro, Kozo Nakamura, Yoshio Takatori, Hiroshi Kawaguchi, Tomohiro Konno, Tomiharu Matsushita, Shuji Kusumoto
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Publication number: 20090306781Abstract: The present invention provides a bearing material that is excellent in durability and is capable of maintaining wear resistance over a long period of time. The bearing material of the present invention is a high wear-resistance bearing material 10 for being used under a humid environment comprising: a base body 12 made of a polymer material having a methylene group; and a polymer layer 30 covering a bearing surface 16 of the substrate 12, the polymer layer 30 comprising polymer chains which have a phosphorylcholine group and are grafted from the bearing surface 16, wherein a phosphoric index of the sliding surface 16 which is calculated by dividing a peak intensity of phosphate group in an infrared spectrum measured on the sliding surface by a peak intensity of the methylene group therein is not less than 0.28.Type: ApplicationFiled: February 5, 2007Publication date: December 10, 2009Inventors: Masayuki Kyomoto, Toru Moro, Kazuhiko Ishihara, Tomohiro Konno, Kozo Nakamura, Yoshio Takatori, Hiroshi Kawaguchi, Hiroaki Takadama, Makoto Kondo, Noboru Yamawaki, Takeshi Nizuka, Masami Hashimoto
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Publication number: 20040243249Abstract: An artificial joint member made of a polymeric material including a portion made of a polymeric substance has a sliding surface composed of a polymer having phosphoryl choline groups. With such an arrangement, the artificial joint member is provided with a sliding part capable of keeping a satisfactory lubricating state for a long time.Type: ApplicationFiled: March 10, 2004Publication date: December 2, 2004Inventors: Kazuhiko Ishihara, Toru Moro, Kozo Nakamura, Yoshio Takatori, Hiroshi Kawaguchi, Tomohiro Konno, Tomiharu Matsushita, Shuji Kusumoto